Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lipase

Gene

LIPN

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei173NucleophileUniRule annotation1
Active sitei344Charge relay systemUniRule annotation1
Active sitei373Charge relay systemUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processLipid degradationUniRule annotation, Lipid metabolism

Protein family/group databases

MEROPSiS33.018

Names & Taxonomyi

Protein namesi
Recommended name:
LipaseUniRule annotation
Gene namesi
Name:LIPNImported
ORF Names:EGM_18181Imported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000009130 Componenti: Chromosome 9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501430406021 – 398LipaseSequence analysisAdd BLAST378

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 379AB hydrolase-1InterPro annotationAdd BLAST301

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00550000074328

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
IPR025483 Lipase_euk
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
PIRSFiPIRSF000862 Steryl_ester_lip, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

G7PDH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMWLLLTTTC LICGTLNVGG FLDLENEVNP EVWMNTSEII IYNGYPSEEY
60 70 80 90 100
EVTTEDGYIL LVNRIPYGRR HIRSTGPRPV VYMQHALFAD NAYWLENYAN
110 120 130 140 150
GSLGFLLADA GYDVWMGNSR GNTWSRRHKT LSETDEKFWA FSFDEMAKYD
160 170 180 190 200
LPGVIDFIVN KTGQEKLYFI GHSLGTTIGF VAFSTMPELA QRIKMNFALG
210 220 230 240 250
PVISFKYPTG IFTSFFLLPN SIIKAVFGTK GFFLEDKKKK IPSTKICNNK
260 270 280 290 300
ILWLICSEFM SLWAGSNKKN MNQSRMDVYM SHAPTGSSIQ NILHIKQLYQ
310 320 330 340 350
SDEFRAYDWG NEADNMKHYN QSHPPIYDLT AMKVPTAIWA GGHDVLVTPQ
360 370 380 390
DVARILPQIK SLHYFKLLPD WNHFDFVWGL DAPQRMYSEI IALMKAYS
Length:398
Mass (Da):45,651
Last modified:January 25, 2012 - v1
Checksum:iE1D8B16F668328A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01071906 Genomic DNA No translation available.
AQIA01071907 Genomic DNA No translation available.
AQIA01071908 Genomic DNA No translation available.
CM001284 Genomic DNA Translation: EHH64856.1
RefSeqiXP_005565948.1, XM_005565891.2

Genome annotation databases

EnsembliENSMFAT00000001153; ENSMFAP00000026971; ENSMFAG00000044901
GeneIDi102137951
KEGGimcf:102137951

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01071906 Genomic DNA No translation available.
AQIA01071907 Genomic DNA No translation available.
AQIA01071908 Genomic DNA No translation available.
CM001284 Genomic DNA Translation: EHH64856.1
RefSeqiXP_005565948.1, XM_005565891.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS33.018

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMFAT00000001153; ENSMFAP00000026971; ENSMFAG00000044901
GeneIDi102137951
KEGGimcf:102137951

Organism-specific databases

CTDi643418

Phylogenomic databases

GeneTreeiENSGT00550000074328

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
IPR025483 Lipase_euk
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
PIRSFiPIRSF000862 Steryl_ester_lip, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG7PDH4_MACFA
AccessioniPrimary (citable) accession number: G7PDH4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: April 25, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again