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Protein
Submitted name:

Rho GTPase activating protein 42

Gene

ARHGAP42

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Rho GTPase activating protein 42Imported
Gene namesi
Name:ARHGAP42Imported
ORF Names:EGK_06816Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 14

Expressioni

Gene expression databases

ExpressionAtlasiG7NBQ3 baseline

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 374PHInterPro annotationAdd BLAST110
Domaini376 – 572Rho-GAPInterPro annotationAdd BLAST197
Domaini816 – 874SH3InterPro annotationAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili87 – 107Sequence analysisAdd BLAST21
Coiled coili225 – 259Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1451 Eukaryota
ENOG410YJPS LUCA
GeneTreeiENSGT00930000150818
KOiK20651

Family and domain databases

Gene3Di1.10.555.10, 1 hit
1.20.1270.60, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00620 RhoGAP, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G7NBQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLPTLEFSD SYLDSPDFRE RLQCHEIELE RTNKFIKELI KDGSLLIGAL
60 70 80 90 100
RNLSMAVQKF SQSLQDFQFE CIGDAETDDE ISIAQSLKEF ARLLIAVEEE
110 120 130 140 150
RRRLIQNAND VLIAPLEKFR KEQIGAAKDG KKKFDKESEK YYSILEKHLN
160 170 180 190 200
LSAKKKESHL QEADTQIDRE HQNFYEASLE YVFKIQEVQE KKKFEFVEPL
210 220 230 240 250
LSFLQGLFTF YHEGYELAQE FAPYKQQLQF NLQNTRNNFE STRQEVERLM
260 270 280 290 300
QRMKSANQDY RPPSQWTMEG YLYVQEKRPL GFTWIKHYCT YDKGSKTFTM
310 320 330 340 350
SVSEMKSSGK MNGLVTSSPE MFKLKSCIRR KTDSIDKRFC FDIEVVERHG
360 370 380 390 400
IITLQAFSEA NRKLWLEAMD GKEPIYTLPA IISKKEEMYL NEAGFNFVRK
410 420 430 440 450
CIQAVETRGI TILGLYRIGG VNSKVQKLMN TIFSPKSPPD IDIDIELWDN
460 470 480 490 500
KTITSGLKNY LRCLAEPLMT YKLHKDFIIA VKSDDQNYRV EAVHALVHKL
510 520 530 540 550
PEKNREMLDI LIKHLVKVSL HSQQNLMTVS NLGVIFGPTL MRAQEETVAA
560 570 580 590 600
MMNIKFQNIV VEILIEHYEK IFHTAPDPSI PLPQPQSRSG SRRTRAICLS
610 620 630 640 650
TGSRKPRGRY TPCLAEPDSD SYSSSPDSTP MGSIESLSSH SSEQNSTTKS
660 670 680 690 700
ASCQPREKSG GIPWIATPSS SNGQKSLGLW TTSPESSSRE DATKTDAESD
710 720 730 740 750
CQSVASVTSP GDVSPPIDLV KKGPYGLSGL KRASASSLRS ISAAEGNKSY
760 770 780 790 800
SGSIQSLNSV GSKETPKASP NPDLPPKMCR RLRLDTASSN GYQRPGSVVA
810 820 830 840 850
AKAQLFENVG SPKPVSSGRQ AKAMYSCKAE HSHELSFPQG AIFSNVYPSV
860 870
EPGWLKATYE GKTGLVPENY VVFL
Length:874
Mass (Da):98,522
Last modified:January 25, 2012 - v1
Checksum:iD42CD63BAA0CCCAD
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5QEF8A0A1D5QEF8_MACMU
Uncharacterized protein
ARHGAP42
878Annotation score:
F6Z7C0F6Z7C0_MACMU
Uncharacterized protein
ARHGAP42
844Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03013283 Genomic DNA No translation available.
JSUE03013284 Genomic DNA No translation available.
JSUE03013285 Genomic DNA No translation available.
CM001266 Genomic DNA Translation: EHH23364.1
RefSeqiXP_002799830.1, XM_002799784.2
UniGeneiMmu.26458

Genome annotation databases

EnsembliENSMMUT00000062360; ENSMMUP00000043511; ENSMMUG00000022603
GeneIDi703141
KEGGimcc:703141

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03013283 Genomic DNA No translation available.
JSUE03013284 Genomic DNA No translation available.
JSUE03013285 Genomic DNA No translation available.
CM001266 Genomic DNA Translation: EHH23364.1
RefSeqiXP_002799830.1, XM_002799784.2
UniGeneiMmu.26458

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000062360; ENSMMUP00000043511; ENSMMUG00000022603
GeneIDi703141
KEGGimcc:703141

Organism-specific databases

CTDi143872

Phylogenomic databases

eggNOGiKOG1451 Eukaryota
ENOG410YJPS LUCA
GeneTreeiENSGT00930000150818
KOiK20651

Gene expression databases

ExpressionAtlasiG7NBQ3 baseline

Family and domain databases

Gene3Di1.10.555.10, 1 hit
1.20.1270.60, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00620 RhoGAP, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG7NBQ3_MACMU
AccessioniPrimary (citable) accession number: G7NBQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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