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UniProtKB - G7MKW6 (G7MKW6_MACMU)
Protein
Fork-head domain-containing protein
Gene
EGK_11492
Organism
Macaca mulatta (Rhesus macaque)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 467 – 540 | Fork-headPROSITE-ProRule annotationAdd BLAST | 74 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
- sequence-specific DNA binding Source: InterPro
GO - Biological processi
- animal organ development Source: UniProt
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation, RepressorARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Fork-head domain-containing proteinInterPro annotation |
Gene namesi | ORF Names:EGK_11492Imported |
Organismi | Macaca mulatta (Rhesus macaque)Imported |
Taxonomic identifieri | 9544 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 467 – 540 | Fork-headInterPro annotationAdd BLAST | 74 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 272 – 300 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 392 – 424 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 613 – 679 | DisorderedSequence analysisAdd BLAST | 67 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 350 – 370 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 272 – 288 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 392 – 407 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 613 – 627 | Polar residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerARBA annotationFamily and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR032354, FOXP-CC IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit PF16159, FOXP-CC, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
i Sequence
Sequence statusi: Complete.
G7MKW6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFQCVFSSSV LQPHSTSCLF KHLFYHSATP ASQKQPEPIY SKKTEIQRQT
60 70 80 90 100
VRAPFAKLFI FSALQVARQL LLQQQQQQQV SGLKSPKRND KQPALQVPVS
110 120 130 140 150
VAMMTPQVIT PQQMQQILQQ QVLSPQQLQV LLQQQQALML QQQQLQEFYK
160 170 180 190 200
KQQEQLQLQL LQQQHAGKQP KEQQQVATQQ LAFQQQLLQM QQLQQQHLLS
210 220 230 240 250
LQRQGLLTIQ PGQPALPLQP LAQGMIPTEL QQLWKEVTSA HTAEETTGNN
260 270 280 290 300
HSSLDLTTTC VSSSAPSKTS LIMNPHASTN GQLSVHTPKR ESLSHEEHPH
310 320 330 340 350
SHPLYGHGVC KWPGCEAVCE DFQSFLKHLN SEHALDDRST AQCRVQMQVV
360 370 380 390 400
QQLELQLAKD KERLQAMMTH LHVKSTEPKA APQPLNLVSS VTLSKSASEA
410 420 430 440 450
SPQSLPHTPT TPTAPLTPVT QGPSVITTTS MHTVGPIRRR YSDKYNVPIS
460 470 480 490 500
SADIAQNQEF YKNAEVRPPF TYASLIRQAI LESPEKQLTL NEIYNWFTRM
510 520 530 540 550
FAYFRRNAAT WKNAVRHNLS LHKCFVRVEN VKGAVWTVDE VEFQKRRPQK
560 570 580 590 600
ISGNPSLIKN MQSSHAYCTP LNAALQASMA ENSIPLYTTA SMGNPTLGNL
610 620 630 640 650
ASAIREELNG AMEHTNSNES DSSPGRSPMQ AVHPVHVKEE PLDPEEAEGP
660 670
LSLVTTANHS PDFDHDRDYE DEPVNEDME
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM001254 Genomic DNA Translation: EHH16236.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM001254 Genomic DNA Translation: EHH16236.1 |
3D structure databases
SMRi | G7MKW6 |
ModBasei | Search... |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR032354, FOXP-CC IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit PF16159, FOXP-CC, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G7MKW6_MACMU | |
Accessioni | G7MKW6Primary (citable) accession number: G7MKW6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 25, 2012 |
Last sequence update: | January 25, 2012 | |
Last modified: | January 19, 2022 | |
This is version 54 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |