Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Transient receptor potential channel

Gene

gon-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cation transmembrane transporter activity Source: WormBase
  • ion channel activity Source: InterPro

GO - Biological processi

  • cation transport Source: WormBase
  • defecation Source: WormBase
  • mitotic cell cycle Source: WormBase

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Transient receptor potential channelImported
Gene namesi
Name:gon-2Imported
ORF Names:CELE_T01H8.5Imported, T01H8.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiT01H8.5e ; CE42821 ; WBGene00001651 ; gon-2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei896 – 920HelicalSequence analysisAdd BLAST25
Transmembranei932 – 949HelicalSequence analysisAdd BLAST18
Transmembranei970 – 989HelicalSequence analysisAdd BLAST20
Transmembranei1036 – 1054HelicalSequence analysisAdd BLAST19
Transmembranei1132 – 1153HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiWBGene00001651 Expressed in 5 organ(s), highest expression level in material anatomical entity

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini907 – 1158Ion_transInterPro annotationAdd BLAST252

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3614 Eukaryota
ENOG410XR5B LUCA
GeneTreeiENSGT00760000119127

Family and domain databases

InterProiView protein in InterPro
IPR005821 Ion_trans_dom
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

G5EGJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLFEHVWQI SPPRLIITVH GGTSNFDLQP KLARVFRKGL LKAASTTGAW
60 70 80 90 100
IITSGCDTGV VKHVAAALEG AQSAQRNKIV CIGIAPWGLL KKREDFIGQD
110 120 130 140 150
KTVPYYPSSS KGRFTGLNNR HSYFLLVDNG TVGRYGAEVI LRKRLEMYIS
160 170 180 190 200
QKQKIFGGTR SVPVVCVVLE GGSCTIRSVL DYVTNVPRVP VVVCDGSGRA
210 220 230 240 250
ADLLAFAHQN VTEDGLLPDD IRRQVLLLVE TTFGCSEAAA HRLLHELTVC
260 270 280 290 300
AQHKNLLTIF RLGEQGEHDV DHAILTALLK GQNLSAADQL ALALAWNRVD
310 320 330 340 350
IARSDVFAMG HEWPQAALHN AMMEALIHDR VDFVRLLLEQ GINMQKFLTI
360 370 380 390 400
SRLDELYNTD KGPPNTLFYI VRDVVRVRQG YRFKLPDIGL VIEKLMGNSY
410 420 430 440 450
QCSYTTSEFR DKYKQRMKRV KHAQKKAMGV FSSRPSRTGS GIASRQSTEG
460 470 480 490 500
MGGVGGGSSV AGVFGNSFGN QDPPLDPHVN RSALSGSRAL SNHILWRSAF
510 520 530 540 550
RGNFPANPMR PPNLGDSRDC GSEFDEELSL TSASDGSQTE PDFRYPYSEL
560 570 580 590 600
MIWAVLTKRQ DMAMCMWQHG EEAMAKALVA CRLYKSLATE AAEDYLEVEI
610 620 630 640 650
CEELKKYAEE FRILSLELLD HCYHVDDAQT LQLLTYELSN WSNETCLALA
660 670 680 690 700
VIVNNKHFLA HPCCQILLAD LWHGGLRMRT HSNIKVVLGL ICPPFIQMLE
710 720 730 740 750
FKTREELLNQ PQTAAEHQND MNYSSSSSSS SSSSSSSSSS DSSSFEDDDD
760 770 780 790 800
ENNAHNHDQK RTRKTSQGSA QSLNITSLFH SRRRKAKKNE KCDRETDASA
810 820 830 840 850
CEAGNRQIQN GGLTAEYGTF GESNGVSPPP PYMRANSRSR YNNRSDMSKT
860 870 880 890 900
SSVIFGSDPN LSKLQKSNIT STDRPNPMEQ FQGTRKIKMR RRFYEFYSAP
910 920 930 940 950
ISTFWSWTIS FILFITFFTY TLLVKTPPRP TVIEYILIAY VAAFGLEQVR
960 970 980 990 1000
KIIMSDAKPF YEKIRTYVCS FWNCVTILAI IFYIVGFFMR CFGSVAYGRV
1010 1020 1030 1040 1050
ILACDSVLWT MKLLDYMSVH PKLGPYVTMA GKMIQNMSYI IVMLVVTLLS
1060 1070 1080 1090 1100
FGLARQSITY PDETWHWILV RNIFLKPYFM LYGEVYADEI DTCGDEAWDQ
1110 1120 1130 1140 1150
HLENGGPVIL GNGTTGLSCV PGYWIPPLLM TFFLLIANIL LMSMLIAIFN
1160 1170 1180 1190 1200
HIFDATDEMS QQIWLFQRYK QVMEYESTPF LPPPLTPLYH GVLILQFVRT
1210 1220 1230 1240 1250
RLSCSKSQER NPMFDFSLKL FLDNDQIEKL HDFEEDCMED LARQKLNEKN
1260 1270 1280 1290 1300
TSNEQRILRA DIRTDQILNR LIDLQAKESM GRDVINDVES RLASVEKAQN
1310 1320 1330 1340 1350
EILECVRALL NQNNAPTAIG RCFSPSPDPL VETANGTPGP LLLKLPGTDP
1360 1370 1380 1390 1400
ILEEKDHDSG ENSNSLPPGR IRRNRTATIC GGYVSEERNM MLLSPKPSDV
1410 1420 1430 1440 1450
SGIPQQRLMS VTSMDPLPLP LAKLSTMSIR RRHEEYTSIT DSIAIRHPER
1460 1470 1480 1490 1500
RIRNNRSNSS EHDESAVDSE GGGNVTSSPR KRSTRDLRMT PSSQVEESTS
1510 1520 1530 1540 1550
RDQIFEIDHP EHEEDEAQAD CELTDVITEE EDEEEDDEED DSHERHHIHP
1560 1570 1580 1590 1600
RRKSSRQNRQ PSHTLETDLS EGEEVDPLDV LKMKELPIIH QILNEEEQAG
1610 1620
APHSTPVIAS PSSSRADLTS QKCSDV
Length:1,626
Mass (Da):183,066
Last modified:December 14, 2011 - v1
Checksum:iF0885FB3B033EF7C
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q93971TRPG_CAEEL
Transient receptor potential channe...
gon-2 T01H8.5/T01H8.3/T01H8.4
2,032Annotation score:
G5EGP7G5EGP7_CAEEL
Transient receptor potential channe...
gon-2 CELE_T01H8.5, T01H8.5
1,971Annotation score:
G5EE91G5EE91_CAEEL
Transient receptor potential channe...
gon-2 CELE_T01H8.5, T01H8.5
1,931Annotation score:
A5JYU8A5JYU8_CAEEL
Transient receptor potential channe...
gon-2 CELE_T01H8.5, T01H8.5
221Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAQ76491.1
RefSeqiNP_001129788.1, NM_001136316.2
UniGeneiCel.19771

Genome annotation databases

EnsemblMetazoaiT01H8.5e; T01H8.5e; WBGene00001651
GeneIDi172646

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAQ76491.1
RefSeqiNP_001129788.1, NM_001136316.2
UniGeneiCel.19771

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT01H8.5e; T01H8.5e; WBGene00001651
GeneIDi172646

Organism-specific databases

CTDi172646
WormBaseiT01H8.5e ; CE42821 ; WBGene00001651 ; gon-2

Phylogenomic databases

eggNOGiKOG3614 Eukaryota
ENOG410XR5B LUCA
GeneTreeiENSGT00760000119127

Gene expression databases

BgeeiWBGene00001651 Expressed in 5 organ(s), highest expression level in material anatomical entity

Family and domain databases

InterProiView protein in InterPro
IPR005821 Ion_trans_dom
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG5EGJ6_CAEEL
AccessioniPrimary (citable) accession number: G5EGJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: October 10, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again