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Protein
Submitted name:

Aminopeptidase

Gene

CELE_F49B2.6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • metalloaminopeptidase activity Source: GO_Central
  • peptide binding Source: GO_Central
  • zinc ion binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionAminopeptidaseImported, Hydrolase, Protease

Protein family/group databases

MEROPSiM01.A15

Names & Taxonomyi

Protein namesi
Submitted name:
AminopeptidaseImported
Gene namesi
ORF Names:CELE_F49B2.6Imported, F49B2.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF49B2.6 ; CE40456 ; WBGene00009865

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 63HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiG5EGH4
PaxDbiG5EGH4
PeptideAtlasiG5EGH4

Expressioni

Gene expression databases

BgeeiWBGene00009865 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Interactioni

Protein-protein interaction databases

STRINGi6239.F49B2.6

Structurei

3D structure databases

ProteinModelPortaliG5EGH4
SMRiG5EGH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini411 – 633Peptidase_M1InterPro annotationAdd BLAST223
Domaini725 – 1022ERAP1_CInterPro annotationAdd BLAST298

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili116 – 181Sequence analysisAdd BLAST66

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1046 Eukaryota
COG0308 LUCA
GeneTreeiENSGT00760000119082
InParanoidiG5EGH4
OMAiYLELFYH
OrthoDBiEOG091G01GH
PhylomeDBiG5EGH4

Family and domain databases

CDDicd09601 M1_APN_2, 1 hit
InterProiView protein in InterPro
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR014782 Peptidase_M1_N
PANTHERiPTHR11533 PTHR11533, 1 hit
PfamiView protein in Pfam
PF11838 ERAP1_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE

Sequencei

Sequence statusi: Complete.

G5EGH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLYEEGETHD GLSKCLFSTI WTPSNPYRHT SSHRRTRVCV AITFGLLMFG
60 70 80 90 100
LGVSVGAFLH AVMFPDGSPS ILSLPSFLKS DAPMDADNST LINLRIAGAE
110 120 130 140 150
LGSSVELEDT TVGSEEEEMV EEGDEEEDEV EEKSEESEEE EEKIKKKRRG
160 170 180 190 200
KKEKKEKVVE EVEEEEEHEE TEEQEEEQSG EKFVKANKEC TNITWYSSRL
210 220 230 240 250
PRTAEPIDYD LTLHPNLTNG EVEASVSIRI LIKNDTKLLI LNAENLEMKS
260 270 280 290 300
FDITKKGAKV KADFVKCAVM TQWAWKLAKR LHKGDHIVLT IYYSAQMKSD
310 320 330 340 350
LQGLYFSTHL GTDGKKTKSA ATQFEPTFAR KMLPCFDEPN FKATFQVAII
360 370 380 390 400
RNPHHIARSN MNILISKEYK NGLIKDVFEK SVKMSTYLLA VAVLDGYGYI
410 420 430 440 450
KRLTRNTQKA IEVRLYAPQD MLTGQSEFGL DTTIRALEFF EDYFNISYPL
460 470 480 490 500
DKIDLLALDD FSEGAMENWG LVTFRDSALL FNERKASVVA KEHIALIICH
510 520 530 540 550
EIAHQWFGNL VTMDWWNEVF LNEGFANYME YKCVEHLFPD WSIMSRFYAE
560 570 580 590 600
NLAFSQEPDG FLSSRAIESD DDDSLLNLFD AINYHKAAAI IHMIAEMAGQ
610 620 630 640 650
KNFQNALVEY LNKYAYSNAI GVDLWKIVEK HANLQGTVSI PDLAKAYTTQ
660 670 680 690 700
VGYPLLTVER TDEGVLVHNQ TRFLFAEGDK AEEKRGDWKW PIPISYRDSE
710 720 730 740 750
HRRKKQHWIQ ADDKNVTWET TSNDWLILNT GGVGYFKVLY DPETYRKLVK
760 770 780 790 800
QLQRNHTTIS PIDRSMILVD SFDLSKTSLL NISVYFDLLE YVEKETDKMT
810 820 830 840 850
WSIVGKQLRT IEALIEESDY LDIYQDFQRS LIMRLYESLD WDEQGANPNQ
860 870 880 890 900
KRLQVDIFAV ACRLQIKDCT KQAYQRYLQW VSSGVRNPEH HMIALMEGVK
910 920 930 940 950
QGETTAWERI WKAYKTATSP SEKNNIIGAL TSTKDASLIN RLLKYCLDGK
960 970 980 990 1000
IKANLIPRVF SYFSLNQSTR NIVWKFFKTH FEQFHGILGK GSLMASCVKC
1010 1020 1030 1040 1050
LAEPLSTETE LEEVKEFLKS QKFAEDGLIK MEMTYEQIEL NIQWRKLNEG
1060 1070 1080
QLGKWISRWD ERRRTLYRRK RHRHHHKPLS VF
Length:1,082
Mass (Da):124,990
Last modified:December 14, 2011 - v1
Checksum:iEDD7229B623F8A1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB04428.2
PIRiT22406
RefSeqiNP_493503.2, NM_061102.3
UniGeneiCel.24087

Genome annotation databases

EnsemblMetazoaiF49B2.6; F49B2.6; WBGene00009865
GeneIDi173297
KEGGicel:CELE_F49B2.6

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB04428.2
PIRiT22406
RefSeqiNP_493503.2, NM_061102.3
UniGeneiCel.24087

3D structure databases

ProteinModelPortaliG5EGH4
SMRiG5EGH4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F49B2.6

Protein family/group databases

MEROPSiM01.A15

Proteomic databases

EPDiG5EGH4
PaxDbiG5EGH4
PeptideAtlasiG5EGH4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF49B2.6; F49B2.6; WBGene00009865
GeneIDi173297
KEGGicel:CELE_F49B2.6

Organism-specific databases

CTDi173297
WormBaseiF49B2.6 ; CE40456 ; WBGene00009865

Phylogenomic databases

eggNOGiKOG1046 Eukaryota
COG0308 LUCA
GeneTreeiENSGT00760000119082
InParanoidiG5EGH4
OMAiYLELFYH
OrthoDBiEOG091G01GH
PhylomeDBiG5EGH4

Gene expression databases

BgeeiWBGene00009865 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd09601 M1_APN_2, 1 hit
InterProiView protein in InterPro
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR014782 Peptidase_M1_N
PANTHERiPTHR11533 PTHR11533, 1 hit
PfamiView protein in Pfam
PF11838 ERAP1_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE
ProtoNetiSearch...

Entry informationi

Entry nameiG5EGH4_CAEEL
AccessioniPrimary (citable) accession number: G5EGH4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 7, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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