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UniProtKB - G5EGF4 (G5EGF4_CAEEL)
Protein
Submitted name:
GATA-like transcription factor ELT-5
Gene
egl-18
Organism
Caenorhabditis elegans
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: WormBase
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- zinc ion binding Source: InterPro
GO - Biological processi
- cell fate commitment Source: GO_Central
- cell fate specification Source: WormBase
- membrane fusion Source: WormBase
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- nematode larval development Source: WormBase
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- tissue development Source: UniProt
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: GATA-like transcription factor ELT-5ImportedSubmitted name: GATA-type domain-containing proteinImported |
Gene namesi | Name:egl-18Imported ORF Names:CELE_F55A8.1Imported, F55A8.1Imported |
Organismi | Caenorhabditis elegansImported |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | F55A8.1a ; CE28339 ; WBGene00001186 ; egl-18 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: WormBase
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | WBGene00001186, Expressed in multi-cellular organism and 5 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 260 – 313 | GATA-typeInterPro annotationAdd BLAST | 54 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 65 – 122 | DisorderedSequence analysisAdd BLAST | 58 | |
Regioni | 148 – 197 | DisorderedSequence analysisAdd BLAST | 50 | |
Regioni | 240 – 264 | DisorderedSequence analysisAdd BLAST | 25 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 67 – 88 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 148 – 174 | Polar residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 178 – 196 | Basic and acidic residuesSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
HOGENOMi | CLU_685583_0_0_1 |
OMAi | HIQQRYR |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR039355, Transcription_factor_GATA IPR000679, Znf_GATA IPR013088, Znf_NHR/GATA |
PANTHERi | PTHR10071, PTHR10071, 1 hit |
Pfami | View protein in Pfam PF00320, GATA, 1 hit |
PRINTSi | PR00619, GATAZNFINGER |
SMARTi | View protein in SMART SM00401, ZnF_GATA, 1 hit |
PROSITEi | View protein in PROSITE PS50114, GATA_ZN_FINGER_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
G5EGF4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSISIMTETR PESAEQQHHE VLQRPSDEPC SGCKQLQKDV AKTISMVMER
60 70 80 90 100
MDKLQYRLDE LLKENNELKS SSVSSGKASP SPAESRSSPK LVETVVAPVS
110 120 130 140 150
GARKRKPKER SPPAAASPLP DFSNLMNGFM FDPLNMSNPN GMMQLLSMVQ
160 170 180 190 200
QQQQQQQHHQ HIENQQSVSP PQSKSVKIED PMDQDVKQEE SERSDIPTAT
210 220 230 240 250
EAQNLLDALT AQFSSNGQAT STTSPPSSSS QVQAVIEAVA TPSSQSQDSS
260 270 280 290 300
MFEKTETSGD PNAARCSNCR TDKTTAWRRD AEGKLVCNPC GLYYRLHKVR
310 320 330 340 350
RPIEMRKNHI QQRYRRKNKE KESSAATQIF NQLLTQMPTM ATGGVSTDGA
360 370
INTFNLLEQI SQFTQAQELM NSSATF
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketU4PMB4 | U4PMB4_CAEEL | GATA-type domain-containing protein | egl-18 CELE_F55A8.1, F55A8.1 | 379 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF353302 mRNA Translation: AAK32716.1 BX284604 Genomic DNA Translation: CCD71858.1 |
PIRi | E88640 |
RefSeqi | NP_500143.1, NM_067742.5 |
Genome annotation databases
EnsemblMetazoai | F55A8.1a.1; F55A8.1a.1; WBGene00001186 F55A8.1a.2; F55A8.1a.2; WBGene00001186 |
GeneIDi | 176992 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF353302 mRNA Translation: AAK32716.1 BX284604 Genomic DNA Translation: CCD71858.1 |
PIRi | E88640 |
RefSeqi | NP_500143.1, NM_067742.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | G5EGF4, 6 interactors |
Genome annotation databases
EnsemblMetazoai | F55A8.1a.1; F55A8.1a.1; WBGene00001186 F55A8.1a.2; F55A8.1a.2; WBGene00001186 |
GeneIDi | 176992 |
Organism-specific databases
CTDi | 176992 |
WormBasei | F55A8.1a ; CE28339 ; WBGene00001186 ; egl-18 |
Phylogenomic databases
HOGENOMi | CLU_685583_0_0_1 |
OMAi | HIQQRYR |
Gene expression databases
Bgeei | WBGene00001186, Expressed in multi-cellular organism and 5 other tissues |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR039355, Transcription_factor_GATA IPR000679, Znf_GATA IPR013088, Znf_NHR/GATA |
PANTHERi | PTHR10071, PTHR10071, 1 hit |
Pfami | View protein in Pfam PF00320, GATA, 1 hit |
PRINTSi | PR00619, GATAZNFINGER |
SMARTi | View protein in SMART SM00401, ZnF_GATA, 1 hit |
PROSITEi | View protein in PROSITE PS50114, GATA_ZN_FINGER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G5EGF4_CAEEL | |
Accessioni | G5EGF4Primary (citable) accession number: G5EGF4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 14, 2011 |
Last sequence update: | December 14, 2011 | |
Last modified: | January 19, 2022 | |
This is version 95 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |