Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 67 (10 Apr 2019)
Sequence version 1 (14 Dec 2011)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

vab-10

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: WormBase
  • structural molecule activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingSAAS annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-6809371 Formation of the cornified envelope

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:vab-10Imported
ORF Names:CELE_ZK1151.1Imported, ZK1151.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
ZK1151.1d ; CE36460 ; WBGene00006876 ; vab-10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006876 Expressed in 5 organ(s), highest expression level in material anatomical entity

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
G5EFW2 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
G5EFW2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
G5EFW2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 146Calponin-homology (CH)InterPro annotationAdd BLAST108
Domaini148 – 255Calponin-homology (CH)InterPro annotationAdd BLAST108
Domaini786 – 843SH3InterPro annotationAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili23 – 43Sequence analysisAdd BLAST21
Coiled coili751 – 771Sequence analysisAdd BLAST21
Coiled coili998 – 1018Sequence analysisAdd BLAST21
Coiled coili1151 – 1171Sequence analysisAdd BLAST21
Coiled coili1318 – 1444Sequence analysisAdd BLAST127

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0516 Eukaryota
COG5069 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164812

Database of Orthologous Groups

More...
OrthoDBi
24858at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
3.90.1290.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR029926 Dystonin-like
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin

The PANTHER Classification System

More...
PANTHERi
PTHR44968 PTHR44968, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF17902 SH3_10, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00250 PLEC, 16 hits
SM00150 SPEC, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS50021 CH, 2 hits
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All

G5EFW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGERYRSHH AVDPSDAQEK EVLDHYELNR EKYNDERDNV QKKTFTKWVN
60 70 80 90 100
KHLSKTDHKI DDLFVDLRDG YALIALLEAL TGERIQKENG YTRFHRIQNV
110 120 130 140 150
QYCLDFLKKK NVSVIRQRLL LESSQHEQMS AKHTTTNSQV SLHGSDATSA
160 170 180 190 200
RDALLQWARR VTAGYPRVNV NNFSSSWRDG LAFNAILHRY RSSAIDWNKI
210 220 230 240 250
SSDSVSNTER LNNAFAAADR EFGVERLLDA EDVDTNNPDE KSIITYVSSL
260 270 280 290 300
YNALPHEPEM SRLQKVQEEY IEEAYEWREW VVRAIQLVDD RHLQGTASEL
310 320 330 340 350
IYELQRFRED DLPPREEQKR RLTLVYEHLE KVMRSTELFA IPHELSAPEL
360 370 380 390 400
QRVWNELQNS IDRRFDVLER HRIQEGNSND LLSRLARGIG ITNEKLDLIL
410 420 430 440 450
KRIEDVEARV DTSPPAAVER TVSEIVDDLN ALESPIARFF EDVEELKSMQ
460 470 480 490 500
HPEANDFYKQ VYGLHQRRTT YLDRLTNQIL VRLGVRTDSL HKENQQRLEN
510 520 530 540 550
MRKTSFSRVE ECIEWVRVRM EKLTTMEFLE DLETLEHVFE QHKFDNRDIQ
560 570 580 590 600
DFRQNVDECI ARQAEVSAED TYEYCELLRV LESEYQQLRD LSAGRMLDLD
610 620 630 640 650
SLIAFVRAAQ LELIWVSERE SIEVTRNWSD IKQLDLPMLT NYYKQLLHEM
660 670 680 690 700
ELREKQYNDV HNQGAALLNQ GHPAIRVIEV YLRQMQSQWD WLLALSKCLE
710 720 730 740 750
EHLRDALNLK SFMEEASDAE AWIQEQSVRL ENNYNRTDFS LEEGERFLRE
760 770 780 790 800
LDEIKEILNK YHQVLMALTE RCASISPLWQ RGERIPHPIK VTALCDYSDE
810 820 830 840 850
NVTIKAGDDV YLLDNSDLIK WTIRDISGAE GQVPSVVFRI PPTDARLTAL
860 870 880 890 900
LNRLLQQFEK LKKLWDKKHR MVRFNMVLNT MRTIQGWDLD TFNSIDPDQR
910 920 930 940 950
DAIMKALNDD ANKLLSELDP NDPLALRLRE ELRRTNEHFW NLLNASQKPP
960 970 980 990 1000
EPDWASQYDQ KMAELLKKLE EAWRELNDAV GKPISRSPED LERVIHAHKR
1010 1020 1030 1040 1050
FEDALQALDS DVANVKELFR QLPNPTPTQR VNHDRLNGLW DDLWDLSRMY
1060 1070 1080 1090 1100
VERIKVLESV LNGMVEVADI VRQHEITLNS FDDLPAALDK LRGHHSQLLE
1110 1120 1130 1140 1150
INMVLKVSKL GAQNEHFSQQ QTVIDQLNRN VALLRQHVSR TRINEGHHPD
1160 1170 1180 1190 1200
VDAIEDEVQK LNVRWENVNS QIASRLLAVE SALQIQMVYR SEYETEMSWL
1210 1220 1230 1240 1250
DTVEETINRL RKPEELRPEQ YQQQLDMLIA EYTNLQEHTQ AIEHVNKEGG
1260 1270 1280 1290 1300
RFIHEAKIFD AKLGQYSDGI VGIHGPGIKS EFRRTKPQPK NGSQIVTEEL
1310 1320 1330 1340 1350
ELLNRRFAQL SSLILERRNT MQVLIQNWKR QKQEEEDRRR AEEEEKRRAF
1360 1370 1380 1390 1400
EAARLKALED AERLRRERED AEARRRAKDD ADRARRMAED AERARREAEE
1410 1420 1430 1440 1450
AERRRREEEE RRRREAEDRK RRQDEEDRRR REEEERRRRE EEEKRRKKPD
1460 1470 1480 1490 1500
FDLKIQKPTM NIEPVVTSAG DEWEIVDPIG DRAKISEVED EMQTFAEETI
1510 1520 1530 1540 1550
TNTQFYEMEG NLNKKTGEVL TFIEAIRQGN LTAAGQFFDI PSASVMSLEE
1560 1570 1580 1590 1600
AAKYGLVEQD LPTVLNTTWG IHHPETRQPI TLSEAIRIGL YDSNIRQFRD
1610 1620 1630 1640 1650
IHTGEILSQS DLMSKGIANW ETVLKLIKEK IMKLPPTSLA NALEKRMVDP
1660 1670 1680 1690 1700
QTGVFKGRTT DMELQLWAAI YHGYLSIENP EHVTTIGTSL TDAIENGFIN
1710 1720 1730 1740 1750
ANNAEFNDRN SNDSFKLRDA VSKRTGLINN DVVEIVQMTD DEKKRVPLGA
1760 1770 1780 1790 1800
ALVRNVIGVK DGKYTNLASR QSMSLKEAHQ DGLIGKALTL EEAAQNKLVD
1810 1820 1830 1840 1850
SSGYFVDRGI LGQRYTLLEA IVAGLIDAEV RHIVDPNEND VISISEAMER
1860 1870 1880 1890 1900
GLLLPNGKIV LEKDEKEFTI PEAVHEGLLT KRVRHSIFNI RGIRNTETSQ
1910 1920 1930 1940 1950
NLSFNEAVEA GVIIPNAERV VDLQTQESFL ITDDRAKNLI EVALHELLTT
1960 1970 1980 1990 2000
PVGIKNDRGA YELNLVRAVS SGIIDPVKGV FFNKNTKHEL STKEAYEQGF
2010 2020 2030 2040 2050
ITLRGALKVF GLLNVPPALV TPAKKLDRTR RIGRPGQEGG ADGNHVTVTL
2060 2070 2080 2090 2100
QDAMRQGLVG NQRYVHGKVD LSLEEALNRG LLDPNSQWIM PDQSKGDGPT
2110 2120 2130 2140 2150
IEEKTTETMT ETGQQLAPKY FPDKNIEESV TTVKRVRTTE TTALGGPGGV
2160 2170 2180 2190 2200
SVYRSIAGGK GALEVPSRGY HIYEAERKGL IDLTNGKISA PNVDRVLSFA
2210 2220 2230 2240 2250
EGIELGIIDA TTIQVSTGGR SVSVKEALEK KIMESDGSVN GRNIEQAVEA
2260 2270 2280 2290 2300
KTIVIDAEPL VPYNNQSKNI IQIPSGNGPI ISFRQVGQPV VEESTQSWEF
2310 2320 2330 2340 2350
DTQQGVFVDN LTGEKLSLER ALATGKVAPE DISVRDGLTG REMPLEEAEK
2360 2370 2380 2390 2400
WGIIDSKNRY YFDKSQNKRM SYTEAAQQHL MYLTGGVPEN ASDAVHTTVK
2410 2420 2430 2440 2450
VQTRTAVAKK EALSSGLPLS DYSLGKALSL GWYDQSAGTF THPETQKQLT
2460 2470 2480 2490 2500
LKEAIMKGLF DPYDTTIVDK KAGKEISLLE AIREEIVDDN AGTVKDTQTG
2510 2520 2530 2540 2550
RVHNFLEAGN LGLVKGKNFG DTLDSSLFSG RLDLGSGSYT RPSGGSSMPI
2560 2570 2580 2590 2600
HEAINRNYVD RSSVSVRDPS SGQQYSYQEA VDRRIVDADR GLIHGGGDST
2610 2620 2630 2640 2650
SFSQGLTSGH LVSSGSSRPT SGNQSRLVEQ RLQLTPFAPN GGAGRSRDGR
2660 2670 2680 2690 2700
HELVDLGGGQ QVQVKVVRGE GGVEKGEYTD PKSGMKFTIQ MHGDPVVTET
2710 2720 2730 2740 2750
KTSVKSTSQV HSVELEPHAE FVGIDRVRDK RNNHVYSLEE ARRLGLAKVD
2760 2770 2780 2790 2800
KKGKQMTRSY QAFRSNIDNA VNNGVVDSHN QKISLENAIH ARIIDIRNLS
2810 2820 2830 2840 2850
YHHPTHGSVD LKTAASQGLV DVTLSEVLPK GIIHPGTGER IDIKRGIELR
2860 2870 2880 2890 2900
IIDAATGKVR DPRDNKTITW IDILKPVYQA IASEGVFDPT KGHHVPVTTA
2910 2920 2930 2940 2950
LNDGLINAST GNYRNSITGE DVPLSDTVDR GLIDRSTYET ITKPFFTDYR
2960 2970 2980 2990 3000
SNRKLNLVEA VRERLIDPKN RTIQLSRQSI VPIAKAVQDG RIPMEIGEKL
3010 3020 3030 3040 3050
RKVDKLNFAE ALGKGLIDSK QNVFTDPDTG RQMSIAQAIQ EGFIDTGSVQ
3060 3070 3080 3090 3100
GIEGNDESNL FNVLQSSDFD ETSGRIYDKK SSLHLTFNDA VRRGVIDGDS
3110 3120 3130 3140 3150
LLHLQATGDL LTLRDALHQN KIDSNGKFVE GANRLKISDA VKSGRLTVIA
3160 3170 3180 3190 3200
SPSEAVQAVT EGVKRRDAEG YKFRISEYDD SQAQRQSVPK FRETVTVSKL
3210 3220 3230 3240 3250
TPQYNEPGLS VRMRQSTTSI GDRASKFLED PSQLAEIQQD FLSSLEAAQF
3260 3270 3280 3290 3300
DTDEKVIEHP HTRQRVSVRE AAETGLLDVQ TGEIVNPDNG RRFSIPRAVH
3310 3320 3330 3340 3350
MKLVGGDAAK RIMEQLNMPV EEVAYATQTI TSSTHRAPSP VFATASVSQP
3360 3370 3380 3390 3400
SGGATTTREF TRTINWHGQP SELRNSQTDP LAAYTTVSSN VTESTEDAPA

WARKQ
Length:3,405
Mass (Da):386,048
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD197CB10461AEB1E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5EDD3G5EDD3_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
4,955Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5EFK7G5EFK7_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
3,322Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5ECG8G5ECG8_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
3,323Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5EFD1G5EFD1_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
1,497Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5ECP9G5ECP9_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
3,424Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5ECG5G5ECG5_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
4,410Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5EEC4G5EEC4_CAEEL
VAB-10A protein
vab-10 CELE_ZK1151.1, ZK1151.1
3,436Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5EFM4G5EFM4_CAEEL
VAB-10B protein
vab-10 CELE_ZK1151.1, ZK1151.1
4,944Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1N7SYR7A0A1N7SYR7_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
4,819Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1N7SYN7A0A1N7SYN7_CAEEL
Uncharacterized protein
vab-10 CELE_ZK1151.1, ZK1151.1
4,946Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAH04740.1

NCBI Reference Sequences

More...
RefSeqi
NP_001021856.1, NM_001026685.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Cel.16101

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ZK1151.1d; ZK1151.1d; WBGene00006876

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
173058

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAH04740.1
RefSeqiNP_001021856.1, NM_001026685.1
UniGeneiCel.16101

3D structure databases

ProteinModelPortaliG5EFW2
SMRiG5EFW2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK1151.1d; ZK1151.1d; WBGene00006876
GeneIDi173058

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
173058
WormBaseiZK1151.1d ; CE36460 ; WBGene00006876 ; vab-10

Phylogenomic databases

eggNOGiKOG0516 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00940000164812
OrthoDBi24858at2759

Enzyme and pathway databases

ReactomeiR-CEL-6809371 Formation of the cornified envelope

Gene expression databases

BgeeiWBGene00006876 Expressed in 5 organ(s), highest expression level in material anatomical entity
ExpressionAtlasiG5EFW2 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
3.90.1290.10, 2 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR029926 Dystonin-like
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
PANTHERiPTHR44968 PTHR44968, 2 hits
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF17902 SH3_10, 1 hit
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00250 PLEC, 16 hits
SM00150 SPEC, 6 hits
SUPFAMiSSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 9 hits
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS50021 CH, 2 hits
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG5EFW2_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EFW2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 10, 2019
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again