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Entry version 83 (17 Jun 2020)
Sequence version 1 (14 Dec 2011)
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Protein

Aminopeptidase ltah-1.1

Gene

ltah-1.1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Aminopeptidase which preferentially removes N-terminal Arg and Lys residues from peptides and proteins.1 Publication

Miscellaneous

Despite its similarity to leukotriene hydrolases, AP-1 does not have leukotriene hydrolase activity. One of the mammalian leukotriene binding sites, 'Tyr-378', is replaced by a Phe residue in AP-1.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.1 Publication EC:3.4.11.6

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

No activity with L-Asp-pNA, L-Glu-pNA or D-Leu-pNA.1 Publication
  1. KM=0.39 mM for L-Lys-pNitroaniline1 Publication
  2. KM=0.43 mM for L-Arg-pNitroaniline1 Publication
  3. KM=0.46 mM for L-Met-pNitroaniline1 Publication
  4. KM=0.90 mM for L-Val-pNitroaniline1 Publication
  5. KM=1.90 mM for L-Pro-pNitroaniline1 Publication
  6. KM=2.00 mM for L-Leu-pNitroaniline1 Publication
  7. KM=5.53 mM for L-Ala-pNitroaniline1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi297Zinc; catalyticPROSITE-ProRule annotation1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei298Proton acceptorBy similarity1
    Metal bindingi301Zinc; catalyticPROSITE-ProRule annotation1
    Metal bindingi320Zinc; catalyticBy similarity1
    Active sitei387Proton donorBy similarity1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionAminopeptidase, Hydrolase, Metalloprotease, Protease
    LigandMetal-binding, Zinc

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-CEL-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
    R-CEL-6798695 Neutrophil degranulation
    R-CEL-9018676 Biosynthesis of D-series resolvins
    R-CEL-9018681 Biosynthesis of protectins
    R-CEL-9018896 Biosynthesis of E-series 18(S)-resolvins
    R-CEL-9020265 Biosynthesis of aspirin-triggered D-series resolvins
    R-CEL-9023661 Biosynthesis of E-series 18(R)-resolvins

    Protein family/group databases

    MEROPS protease database

    More...
    MEROPSi
    M01.025

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Aminopeptidase ltah-1.1Curated (EC:3.4.11.61 Publication)
    Alternative name(s):
    Aminopeptidase-11 Publication
    Short name:
    AP-11 Publication
    Arginine aminopeptidase 1Curated
    Leukotriene A4 hydrolase homolog ltah-1.1Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:ltah-1.11 PublicationImported
    ORF Names:C42C1.11Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

    Organism-specific databases

    WormBase

    More...
    WormBasei
    C42C1.11a ; CE24840 ; WBGene00016589 ; ltah-1.1
    C42C1.11b ; CE33564 ; WBGene00016589 ; ltah-1.1
    C42C1.11c ; CE33565 ; WBGene00016589 ; ltah-1.1

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cytoplasm

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004408001 – 609Aminopeptidase ltah-1.1Add BLAST609

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    G5EFT4

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    G5EFT4

    PeptideAtlas

    More...
    PeptideAtlasi
    G5EFT4

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    WBGene00016589 Expressed in material anatomical entity and 4 other tissues

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    6239.C42C1.11a

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    G5EFT4

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni137 – 139Substrate bindingBy similarity3
    Regioni268 – 273Substrate bindingBy similarity6
    Regioni564 – 566Substrate bindingBy similarity3

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the peptidase M1 family.Curated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG1047 Eukaryota
    COG0308 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00940000156375

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    G5EFT4

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    VSHYDLR

    Database of Orthologous Groups

    More...
    OrthoDBi
    775595at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    G5EFT4

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd09599 M1_LTA4H, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.10.390.10, 1 hit
    1.25.40.320, 1 hit
    2.60.40.1730, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR042097 Aminopeptidase_N-like_N
    IPR016024 ARM-type_fold
    IPR038502 M1_LTA-4_hydro/amino_C_sf
    IPR034015 M1_LTA4H
    IPR001930 Peptidase_M1
    IPR015211 Peptidase_M1_C
    IPR014782 Peptidase_M1_dom
    IPR027268 Peptidase_M4/M1_CTD_sf

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF09127 Leuk-A4-hydro_C, 1 hit
    PF01433 Peptidase_M1, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...
    PRINTSi
    PR00756 ALADIPTASE

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM01263 Leuk-A4-hydro_C, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF48371 SSF48371, 1 hit
    SSF63737 SSF63737, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00142 ZINC_PROTEASE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
    Isoform aImported (identifier: G5EFT4-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MAPPHPRDPS TAANYEQVTV SHYALKWKVD FEKKHIAGDV SITLDVKQDT
    60 70 80 90 100
    ERIVLDTRDL SVQSVALNLN GEPKKAGFTL EDNQALGQKL VITTESLKSG
    110 120 130 140 150
    DRPVLEIKYE SSNNAAALQF LTAEQTTDRV APYLFSQCQA INARSIVPCM
    160 170 180 190 200
    DTPSVKSTYE AEVCVPIGLT CLMSAIGQGS TPSECGKRTI FSFKQPVSIP
    210 220 230 240 250
    SYLLAIVVGH LERKEISERC AVWAEPSQAE ASFYEFAETE KILKVAEDVA
    260 270 280 290 300
    GPYVWGRYDL VVLPATFPFG GMENPCLTFI TPTLLAGDRS LVNVIAHEIS
    310 320 330 340 350
    HSWTGNLVTN FSWEHFWLNE GFTVFLERKI HGKMYGELER QFESESGYEE
    360 370 380 390 400
    ALVRTVNDVF GPDHEYTKLV QNLGNADPDD AFSSVPYEKG SALLFTIEQA
    410 420 430 440 450
    LGDNSRFEQF LRDYIQKYAY KTVSTEEWKE YLYDSFTDKK VILDNIDWNL
    460 470 480 490 500
    WLHKAGLPPK PKYDSTPMQA CKDLAAKWTT EGSEAPTDGE VFAKMSNSQK
    510 520 530 540 550
    LAVLDAVRVN KTMFGDRMPA LTATYKLDQA KNAELKFSWL MLGLETKWSP
    560 570 580 590 600
    IVDASLAFAL AVGRMKYCKP IYRSLFGWSA TRDRAISQFK ANIPNMHPIT

    VKAIQSLLK
    Length:609
    Mass (Da):68,249
    Last modified:December 14, 2011 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCE619691165C19A4
    GO
    Isoform bImported (identifier: G5EFT4-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         131-157: APYLFSQCQAINARSIVPCMDTPSVKS → VIFKFKVHFSKIFDNSGSLSILSMPSN
         158-609: Missing.

    Show »
    Length:157
    Mass (Da):17,405
    Checksum:i7DFB8CF74C76E7B6
    GO
    Isoform cImported (identifier: G5EFT4-3) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         130-130: Missing.

    Show »
    Length:608
    Mass (Da):68,150
    Checksum:i1385FAFEB7EC488D
    GO

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_058995130Missing in isoform c. Curated1
    Alternative sequenceiVSP_058996131 – 157APYLF…PSVKS → VIFKFKVHFSKIFDNSGSLS ILSMPSN in isoform b. CuratedAdd BLAST27
    Alternative sequenceiVSP_058997158 – 609Missing in isoform b. CuratedAdd BLAST452

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AF068201 mRNA Translation: AAC70927.1
    AF068200 Genomic DNA Translation: AAC72891.1
    BX284604 Genomic DNA Translation: CAM36352.1
    BX284604 Genomic DNA Translation: CAM36353.1
    BX284604 Genomic DNA Translation: CAM36354.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    T32899

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001023056.1, NM_001027885.2 [G5EFT4-1]
    NP_001023057.1, NM_001027886.3 [G5EFT4-2]
    NP_001023058.1, NM_001027887.3 [G5EFT4-3]

    Genome annotation databases

    Ensembl metazoan genome annotation project

    More...
    EnsemblMetazoai
    C42C1.11a.1; C42C1.11a.1; WBGene00016589 [G5EFT4-1]
    C42C1.11a.2; C42C1.11a.2; WBGene00016589 [G5EFT4-1]
    C42C1.11b.1; C42C1.11b.1; WBGene00016589 [G5EFT4-2]
    C42C1.11c.1; C42C1.11c.1; WBGene00016589 [G5EFT4-3]
    C42C1.11c.2; C42C1.11c.2; WBGene00016589 [G5EFT4-3]
    C42C1.11c.3; C42C1.11c.3; WBGene00016589 [G5EFT4-3]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    178176

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    cel:CELE_C42C1.11

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AF068201 mRNA Translation: AAC70927.1
    AF068200 Genomic DNA Translation: AAC72891.1
    BX284604 Genomic DNA Translation: CAM36352.1
    BX284604 Genomic DNA Translation: CAM36353.1
    BX284604 Genomic DNA Translation: CAM36354.1
    PIRiT32899
    RefSeqiNP_001023056.1, NM_001027885.2 [G5EFT4-1]
    NP_001023057.1, NM_001027886.3 [G5EFT4-2]
    NP_001023058.1, NM_001027887.3 [G5EFT4-3]

    3D structure databases

    SMRiG5EFT4
    ModBaseiSearch...

    Protein-protein interaction databases

    STRINGi6239.C42C1.11a

    Protein family/group databases

    MEROPSiM01.025

    Proteomic databases

    EPDiG5EFT4
    PaxDbiG5EFT4
    PeptideAtlasiG5EFT4

    Genome annotation databases

    EnsemblMetazoaiC42C1.11a.1; C42C1.11a.1; WBGene00016589 [G5EFT4-1]
    C42C1.11a.2; C42C1.11a.2; WBGene00016589 [G5EFT4-1]
    C42C1.11b.1; C42C1.11b.1; WBGene00016589 [G5EFT4-2]
    C42C1.11c.1; C42C1.11c.1; WBGene00016589 [G5EFT4-3]
    C42C1.11c.2; C42C1.11c.2; WBGene00016589 [G5EFT4-3]
    C42C1.11c.3; C42C1.11c.3; WBGene00016589 [G5EFT4-3]
    GeneIDi178176
    KEGGicel:CELE_C42C1.11

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    178176
    WormBaseiC42C1.11a ; CE24840 ; WBGene00016589 ; ltah-1.1
    C42C1.11b ; CE33564 ; WBGene00016589 ; ltah-1.1
    C42C1.11c ; CE33565 ; WBGene00016589 ; ltah-1.1

    Phylogenomic databases

    eggNOGiKOG1047 Eukaryota
    COG0308 LUCA
    GeneTreeiENSGT00940000156375
    InParanoidiG5EFT4
    OMAiVSHYDLR
    OrthoDBi775595at2759
    PhylomeDBiG5EFT4

    Enzyme and pathway databases

    ReactomeiR-CEL-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
    R-CEL-6798695 Neutrophil degranulation
    R-CEL-9018676 Biosynthesis of D-series resolvins
    R-CEL-9018681 Biosynthesis of protectins
    R-CEL-9018896 Biosynthesis of E-series 18(S)-resolvins
    R-CEL-9020265 Biosynthesis of aspirin-triggered D-series resolvins
    R-CEL-9023661 Biosynthesis of E-series 18(R)-resolvins

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:G5EFT4

    Gene expression databases

    BgeeiWBGene00016589 Expressed in material anatomical entity and 4 other tissues

    Family and domain databases

    CDDicd09599 M1_LTA4H, 1 hit
    Gene3Di1.10.390.10, 1 hit
    1.25.40.320, 1 hit
    2.60.40.1730, 1 hit
    InterProiView protein in InterPro
    IPR042097 Aminopeptidase_N-like_N
    IPR016024 ARM-type_fold
    IPR038502 M1_LTA-4_hydro/amino_C_sf
    IPR034015 M1_LTA4H
    IPR001930 Peptidase_M1
    IPR015211 Peptidase_M1_C
    IPR014782 Peptidase_M1_dom
    IPR027268 Peptidase_M4/M1_CTD_sf
    PfamiView protein in Pfam
    PF09127 Leuk-A4-hydro_C, 1 hit
    PF01433 Peptidase_M1, 1 hit
    PRINTSiPR00756 ALADIPTASE
    SMARTiView protein in SMART
    SM01263 Leuk-A4-hydro_C, 1 hit
    SUPFAMiSSF48371 SSF48371, 1 hit
    SSF63737 SSF63737, 1 hit
    PROSITEiView protein in PROSITE
    PS00142 ZINC_PROTEASE, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

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    ProtoNeti
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    MobiDB: a database of protein disorder and mobility annotations

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    MobiDBi
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    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAMP1_CAEEL
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EFT4
    Secondary accession number(s): A3QMC1, A3QMC2
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2017
    Last sequence update: December 14, 2011
    Last modified: June 17, 2020
    This is version 83 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    3. Peptidase families
      Classification of peptidase families and list of entries
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