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Protein
Submitted name:

MAD (Yeast Mitosis arrest DeFicient) related

Gene

mdf-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • protein kinase binding Source: UniProtKB

GO - Biological processi

  • attachment of mitotic spindle microtubules to kinetochore Source: GO_Central
  • embryo development ending in birth or egg hatching Source: UniProtKB
  • mitotic spindle assembly Source: UniProtKB
  • mitotic spindle assembly checkpoint Source: GO_Central
  • regulation of mitotic sister chromatid separation Source: UniProtKB

Names & Taxonomyi

Protein namesi
Submitted name:
MAD (Yeast Mitosis arrest DeFicient) relatedImported
Submitted name:
MDF-1Imported
Gene namesi
Name:mdf-1Imported
ORF Names:C50F4.11Imported, CELE_C50F4.11Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC50F4.11 ; CE28212 ; WBGene00003160 ; mdf-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiWBGene00003160

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein kinase binding Source: UniProtKB

Protein-protein interaction databases

ComplexPortaliCPX-401 Mitotic checkpoint complex, Mad-1-Mad-2-Bub-1-Bub-3 subcomplex
CPX-402 Mitotic spindle assembly checkpoint mad-1-mad-2 complex
IntActiG5EFM0, 4 interactors
STRINGi6239.C50F4.11

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili13 – 33Sequence analysisAdd BLAST21
Coiled coili74 – 101Sequence analysisAdd BLAST28
Coiled coili109 – 143Sequence analysisAdd BLAST35
Coiled coili383 – 410Sequence analysisAdd BLAST28
Coiled coili418 – 473Sequence analysisAdd BLAST56
Coiled coili505 – 525Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410JMT9 Eukaryota
ENOG41114RH LUCA
OMAiKWEPLMK
OrthoDBiEOG091G05CN

Family and domain databases

InterProiView protein in InterPro
IPR008672 Mad1
PANTHERiPTHR23168 PTHR23168, 1 hit

Sequencei

Sequence statusi: Complete.

G5EFM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYDEDIVDE DEYEESEATM LFAEEIKKQF KREFPLKAET EKKLKQATFR
60 70 80 90 100
RHAPVEARKI NFDMTLSPVA PIELASAKKE KESAQRQLVT LREDHERMKQ
110 120 130 140 150
MMQTNQAKLA EKTIDLETNR EKMLELQEQV ELLKQERDDT IAECNRNVDI
160 170 180 190 200
WTAFGKKYYT WYSMANTQLE SVKLYIDNDG KFENDEEVTR LNAVPRQMYR
210 220 230 240 250
ALEQFDYDDE TVEELGSGSL LEYEGVSFAT RRPPSPETER EIARADQSAA
260 270 280 290 300
NFTLPQSNFT LLEDSNNTIM PEDQTMMTDG CIANRSLIDY EKDEKIQRLL
310 320 330 340 350
LENSVLKDRL NVSSGRAERS MIFEERNRTL EFEKKALHKQ LDSTFSEIEA
360 370 380 390 400
IRIGQAGNLF NIDEKIPSSS DNSAKQLQLI DRITQLITKN NQLEKDFEAA
410 420 430 440 450
TSRMTKVMRE STDCARRNER LEDAFSSERV RSQDLENEKS RLSEQLELSN
460 470 480 490 500
NELEKVKKQL EESQSQLDEV LSMTLTVPAS EPASLPAPTD AGNSTQIFHM
510 520 530 540 550
ASNPLQDAHN EFQASESRKR KLTDAPAGDQ WREQEFAELE KRLYDCESEK
560 570 580 590 600
KVLESSYNLH KELSSKFRQV CIALTGLQIK LKDADEGICT VQSEYEGGSA
610 620 630 640 650
QQFVFKYFYG TPRIDMLDVS CESTTEMLRK WEPLMKKYIG DRNSIPAFLA
660 670
AMTLQLEQDR DFDETMHERT HTFSVLHED
Length:679
Mass (Da):78,633
Last modified:December 14, 2011 - v1
Checksum:iC65E3FD0BE484887
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239998 mRNA Translation: AAF63494.1
BX284605 Genomic DNA Translation: CAA94745.2
PIRiT20117
RefSeqiNP_505462.1, NM_073061.4
UniGeneiCel.19353

Genome annotation databases

EnsemblMetazoaiC50F4.11; C50F4.11; WBGene00003160
GeneIDi179338
KEGGicel:CELE_C50F4.11

Similar proteinsi

Entry informationi

Entry nameiG5EFM0_CAEEL
AccessioniPrimary (citable) accession number: G5EFM0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 18, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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