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Protein
Submitted name:

HUS1 related

Gene

hus-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-176187 Activation of ATR in response to replication stress

Names & Taxonomyi

Protein namesi
Submitted name:
HUS1 relatedImported
Submitted name:
Hus1-like proteinImported
Gene namesi
Name:hus-1Imported
ORF Names:CELE_H26D21.1Imported, H26D21.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiH26D21.1 ; CE20999 ; WBGene00002042 ; hus-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiWBGene00002042 Expressed in 5 organ(s), highest expression level in germ line (C elegans)

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
mrt-2G5EC448EBI-323706,EBI-323732

Protein-protein interaction databases

ComplexPortaliCPX-1615 Checkpoint clamp complex
IntActiG5EFI9, 5 interactors
MINTiG5EFI9
STRINGi6239.H26D21.1

Structurei

3D structure databases

SMRiG5EFI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3999 Eukaryota
ENOG410ZQ9J LUCA
GeneTreeiENSGT00390000000706
KOiK10903
OMAiQVRVDNR
OrthoDBiEOG091G0H06

Family and domain databases

InterProiView protein in InterPro
IPR016580 Cell_cycle_HUS1
IPR007150 Hus1/Mec3
PfamiView protein in Pfam
PF04005 Hus1, 1 hit
PIRSFiPIRSF011312 Cell_cycle_HUS1, 1 hit

Sequencei

Sequence statusi: Complete.

G5EFI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKFSSLLQDT AAIDVFIKIL TSVSKLSKKR CCVKIEKNAL NFICCSGLHD
60 70 80 90 100
GGSWFSLSIP YSSQIFRKFD MVGMNPRNEE QNLIYFELEI DSLVRVLPGG
110 120 130 140 150
HCYLKLKLSK SQKDEPMLSV EVRNPEADIV SHQIPITIIL SKYWNSYSRP
160 170 180 190 200
SIGHRKMSIS MPPPKMMSRF LHVFKNMNTR VVKLTASTSG DLRISTKIET
210 220 230 240 250
GEIDVSFSDL QTNPSETDSQ EDTAKVQLMI RNISPLFQSF ANTRTRAKMN
260 270
IISNRMAEFN FHNEDCVLSY IVGNVSD
Length:277
Mass (Da):31,449
Last modified:December 14, 2011 - v1
Checksum:iC0FB432742FEE292
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF117337 mRNA Translation: AAD22029.1
BX284601 Genomic DNA Translation: CCD68357.1
PIRiB87740
RefSeqiNP_491203.1, NM_058802.6
UniGeneiCel.19590

Genome annotation databases

EnsemblMetazoaiH26D21.1; H26D21.1; WBGene00002042
GeneIDi171939
KEGGicel:CELE_H26D21.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF117337 mRNA Translation: AAD22029.1
BX284601 Genomic DNA Translation: CCD68357.1
PIRiB87740
RefSeqiNP_491203.1, NM_058802.6
UniGeneiCel.19590

3D structure databases

SMRiG5EFI9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-1615 Checkpoint clamp complex
IntActiG5EFI9, 5 interactors
MINTiG5EFI9
STRINGi6239.H26D21.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiH26D21.1; H26D21.1; WBGene00002042
GeneIDi171939
KEGGicel:CELE_H26D21.1

Organism-specific databases

CTDi171939
WormBaseiH26D21.1 ; CE20999 ; WBGene00002042 ; hus-1

Phylogenomic databases

eggNOGiKOG3999 Eukaryota
ENOG410ZQ9J LUCA
GeneTreeiENSGT00390000000706
KOiK10903
OMAiQVRVDNR
OrthoDBiEOG091G0H06

Enzyme and pathway databases

ReactomeiR-CEL-176187 Activation of ATR in response to replication stress

Gene expression databases

BgeeiWBGene00002042 Expressed in 5 organ(s), highest expression level in germ line (C elegans)

Family and domain databases

InterProiView protein in InterPro
IPR016580 Cell_cycle_HUS1
IPR007150 Hus1/Mec3
PfamiView protein in Pfam
PF04005 Hus1, 1 hit
PIRSFiPIRSF011312 Cell_cycle_HUS1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG5EFI9_CAEEL
AccessioniPrimary (citable) accession number: G5EFI9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: October 10, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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