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Entry version 69 (02 Jun 2021)
Sequence version 1 (14 Dec 2011)
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Protein

Myelin regulatory factor homolog 1

Gene

myrf-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Constitutes a precursor of the transcription factor (PubMed:28441531).

Mediates the autocatalytic cleavage that releases the Myelin regulatory factor homolog 1, N-terminal component that specifically activates transcription of genes involved in synaptic rewiring during nervous system maturation (PubMed:28441531).

1 Publication

Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage.

By similarity

Transcription factor that specifically activates expression of genes involved in synaptic rewiring during nervous system maturation (PubMed:28441531).

Specifically required for dorsal D (DD) GABAergic motor neurons synaptic rewiring (PubMed:28441531).

Acts in complex with myrf-2 paralog (PubMed:28441531).

1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi169 – 436NDT80PROSITE-ProRule annotationAdd BLAST268

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding, Hydrolase, Protease
Biological processDifferentiation, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myelin regulatory factor homolog 11 Publication (EC:3.4.-.-By similarity)
Alternative name(s):
Polyglutamine-repeat protein 471 Publication
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:myrf-11 PublicationImported
Synonyms:pqn-471 PublicationImported
ORF Names:F59B10.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
F59B10.1 ; CE36940 ; WBGene00004134 ; myrf-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 658CytoplasmicCuratedAdd BLAST658
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei659 – 679HelicalSequence analysisAdd BLAST21
Topological domaini680 – 931LumenalCuratedAdd BLAST252

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Worms show normal dorsal D (DD) GABAergic motor neurons rewiring but show larval lethality. Worms lacking both myrf-1 and myrf-2 display defective DD neurons rewiring.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi274G → R in ju1121; defective dorsal D (DD) GABAergic motor neurons rewiring. Impairs the function of myrf-2 by obstructing its function in the complex formed between myrf-1 and myrf-2. 1 Publication1
Mutagenesisi483S → A: Prevents cleavage and generation of Myelin regulatory factor homolog 1, N-terminal part. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004413251 – 931Myelin regulatory factor homolog 1Add BLAST931
ChainiPRO_00004413261 – 482Myelin regulatory factor homolog 1, N-terminal1 PublicationAdd BLAST482
ChainiPRO_0000441327483 – 931Myelin regulatory factor homolog 1, C-terminal1 PublicationAdd BLAST449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi797N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi912N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Myelin regulatory factor: Follows autocatalytic cleavage via the peptidase S74 domain. Autoprocessing is apparently constitutive and is essential for transcriptional activity.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei482 – 483Cleavage; by autolysisPROSITE-ProRule annotation1 Publication2

Keywords - PTMi

Autocatalytic cleavage, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
G5EFI7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
G5EFI7

PeptideAtlas

More...
PeptideAtlasi
G5EFI7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed in many tissues, including neuronal, muscle and epidermal stem cells (PubMed:21989027). In neurons, expressed in dorsal D (DD) GABAergic motor neurons (PubMed:28441531).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004134, Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homotrimer (By similarity).

Interacts with myrf-2 (PubMed:28441531).

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-3521, myrf-1-myrf-2 complex

Protein interaction database and analysis system

More...
IntActi
G5EFI7, 3 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F59B10.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
G5EFI7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini483 – 582Peptidase S74PROSITE-ProRule annotationAdd BLAST100

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni29 – 143DisorderedSequence analysisAdd BLAST115

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi29 – 74Polar residuesSequence analysisAdd BLAST46
Compositional biasi85 – 104Polar residuesSequence analysisAdd BLAST20
Compositional biasi111 – 143Polar residuesSequence analysisAdd BLAST33

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Myelin regulatory factor: The peptidase S74 domain, also named Intramolecular Chaperone Auto-processed (ICA) domain or Intramolecular Chaperone Domain (ICD), has protease activity and mediates autocatalytic processing of the protein to generate the Myelin regulatory factor, N-terminal active transcription factor and the Myelin regulatory factor, C-terminal components.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MRF family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3661, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063626

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010255_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G5EFI7

Identification of Orthologs from Complete Genome Data

More...
OMAi
QVKGACY

Database of Orthologous Groups

More...
OrthoDBi
311898at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
G5EFI7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025719, MYRF_C2
IPR026932, MYRF_ICA
IPR024061, NDT80_DNA-bd_dom
IPR008967, p53-like_TF_DNA-bd
IPR030392, S74_ICA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13887, MRF_C1, 1 hit
PF13888, MRF_C2, 1 hit
PF05224, NDT80_PhoG, 1 hit
PF13884, Peptidase_S74, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49417, SSF49417, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51688, ICA, 1 hit
PS51517, NDT80, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

G5EFI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSDLLKGE FDGLNSEHFN MMQYLTQDTD EDDGSMVSPT SSADSMHQNL
60 70 80 90 100
GVQQQQQQML QAQQRQNQNG IFQPRRFPES PAMTDPCGNV SSSSSSSHHS
110 120 130 140 150
DPMFSPNEFN GYAGANDNGN QTMNNIQSQQ LSQQQHQQTR GGNLMMPQQS
160 170 180 190 200
SIHAQMQNMN APQFWSQPGT AAVNQPTNTL AQLNLFNIIR GGADSGMPSP
210 220 230 240 250
VLEMPRKRSR LDTPCETPRI APSFAGIDGF PDENYSQQQA IRFSKFQEEQ
260 270 280 290 300
WSPLYDINAQ PLQQLQVHVV ADKGFNYNSN DNCFVNQKKN HFQISVNVEA
310 320 330 340 350
SDTMPPKYVN FNNRLVPIRD FKLSFCGVKA EMPSSEITIR QSRADRKPHT
360 370 380 390 400
HTPVLFEIQE RRMTKVCVPR LHFSETTLNN QRKQKNRPNP EQKFFLLVVR
410 420 430 440 450
LFASIDESEH GVLIQSYASE KVIVRATNPG SFEPQDTDIG WQRNGGALYT
460 470 480 490 500
QGAVSVGTEH QVESAKLTVA GDIYMSGRII NPSDIRLKEA ITERETAEAI
510 520 530 540 550
ENLLKLRVVD YRYKPEVADI WGLDEQQRHR TGLIAQELQA VLPDAVRDIG
560 570 580 590 600
DYLTIDEGRV FYETVMATQQ LCRMTGDLDS KIDEKVAEIS RRLNEYAVRK
610 620 630 640 650
KLASSMASNL NGDNKSLSYS RCSLTSTATN ATSQPKRSRK HRAIKQAQSC
660 670 680 690 700
GSRLSQGTVV TLVSIMAACL LAMSALYVLD WHNRNYGYHQ HFETNTPSTK
710 720 730 740 750
GELANLVISP ANFMPSFQPD APILLEKCFN PSCKTYCCTD TPPVVEDSRA
760 770 780 790 800
IATHGLDNGD EVYPESPSNR TNGIARAPNL EHMAFETGVE IRIPALNVTL
810 820 830 840 850
DQRYCVERSC NKRKGIFNVF VPVSRYMPDV ALEIEIKAPI SKVVSNCGAF
860 870 880 890 900
PSTEFNHKVC PLSRTQQSES PVPTSTRLFD NIFELSMGSF IQSAYRFRVG
910 920 930
YSTETCFSED SNGSYEEYNL IFYRMCTLSS S
Length:931
Mass (Da):104,463
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC1B7F38712BBF6CD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA88602.3

Protein sequence database of the Protein Information Resource

More...
PIRi
H88293
T22982

NCBI Reference Sequences

More...
RefSeqi
NP_496262.2, NM_063861.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F59B10.1.1; F59B10.1.1; WBGene00004134

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
174614

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F59B10.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA88602.3
PIRiH88293
T22982
RefSeqiNP_496262.2, NM_063861.4

3D structure databases

SMRiG5EFI7
ModBaseiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-3521, myrf-1-myrf-2 complex
IntActiG5EFI7, 3 interactors
STRINGi6239.F59B10.1

Proteomic databases

EPDiG5EFI7
PaxDbiG5EFI7
PeptideAtlasiG5EFI7

Genome annotation databases

EnsemblMetazoaiF59B10.1.1; F59B10.1.1; WBGene00004134
GeneIDi174614
KEGGicel:CELE_F59B10.1

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
174614
WormBaseiF59B10.1 ; CE36940 ; WBGene00004134 ; myrf-1

Phylogenomic databases

eggNOGiKOG3661, Eukaryota
GeneTreeiENSGT00530000063626
HOGENOMiCLU_010255_0_0_1
InParanoidiG5EFI7
OMAiQVKGACY
OrthoDBi311898at2759
PhylomeDBiG5EFI7

Miscellaneous databases

Protein Ontology

More...
PROi
PR:G5EFI7

Gene expression databases

BgeeiWBGene00004134, Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR025719, MYRF_C2
IPR026932, MYRF_ICA
IPR024061, NDT80_DNA-bd_dom
IPR008967, p53-like_TF_DNA-bd
IPR030392, S74_ICA
PfamiView protein in Pfam
PF13887, MRF_C1, 1 hit
PF13888, MRF_C2, 1 hit
PF05224, NDT80_PhoG, 1 hit
PF13884, Peptidase_S74, 1 hit
SUPFAMiSSF49417, SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS51688, ICA, 1 hit
PS51517, NDT80, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYRF1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EFI7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2017
Last sequence update: December 14, 2011
Last modified: June 2, 2021
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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