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Entry version 58 (02 Jun 2021)
Sequence version 1 (14 Dec 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_F12F6.1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CELE_F12F6.1Imported, F12F6.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
F12F6.1 ; CE34803 ; WBGene00008720

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
G5EE62

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
G5EE62

PeptideAtlas

More...
PeptideAtlasi
G5EE62

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00008720, Expressed in multi-cellular organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
G5EE62, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
G5EE62

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28
Regioni102 – 122DisorderedSequence analysisAdd BLAST21
Regioni275 – 312DisorderedSequence analysisAdd BLAST38
Regioni429 – 452DisorderedSequence analysisAdd BLAST24
Regioni681 – 756DisorderedSequence analysisAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili160 – 180Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27Polar residuesSequence analysisAdd BLAST27
Compositional biasi282 – 312Polar residuesSequence analysisAdd BLAST31
Compositional biasi438 – 452Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi681 – 706Polar residuesSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502TH2C, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_332399_0_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
G5EE62

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIHEILD

Database of Orthologous Groups

More...
OrthoDBi
295671at2759

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G5EE62-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTATTEITLK TEPSSNEELS SSPQPVETRK AAVGFDTADQ KLRVISADDI
60 70 80 90 100
LETTEKGELI DVDGRMLTIL EFCDSIESAR ASCEEHANGM NGMGLSSIKY
110 120 130 140 150
EHEDDEDAAQ ETSTSGMGER DGDIDMAELE DETLNEDVTD NGISGLDTSE
160 170 180 190 200
FTGVAALSAI ADLQQQMDEL KNTMRDAIAM SMTDLQNDVD RVNQKQETLS
210 220 230 240 250
QFFKKFIGTS NEGRVQDPFS LKVPSRPFDG SVTRAGNNAS ETVTSYFEQL
260 270 280 290 300
TKMWSNRQTE AEQFVRDELL SNKHLMGAKA KPKPTTSSSS SSNRRQVVDT
310 320 330 340 350
SDGAEQEYTF GTNGTQGKRI VNGIVKTVDK LYYPFITREE EEECLEAANG
360 370 380 390 400
QAPIYAQSLA KILFADTIMM YFKDQDTAKR NWLHDAVDYR FPTLDKPTHV
410 420 430 440 450
SKWKNCSFFI NKNMREAVIA SGTAMPRAPC GPRGPIGPKD KFKNEAKGND
460 470 480 490 500
DTMTGEYEEK VVPVRTPKAR PSTARVNRES SLEGIEWEWL DSDYEKECYQ
510 520 530 540 550
ESLGSQYKYA ELMALRLFST SLTIKFKEQD QTRKDWLRVC VEARFPIEDR
560 570 580 590 600
ERNDQRWKIC GQTCNRNRTK IVGADGREEK YPYFDQSVEE ECFQQCDGQV
610 620 630 640 650
AVYAELMNAK LFPHTQHLFF KDQDLGKRNW LHQILDKRFA STDKIAQTQK
660 670 680 690 700
WKTCTNAINK KLFDGTVTPI TKEALLSSTE HLNNSKSSVP TGISEASSST
710 720 730 740 750
TTPRASLARF ERRMTSEAPS TIGSLKRKAT EESESSSTPA AKRESIRNKQ
760 770 780 790 800
KKEKEQYSAY PYVSEEEEVA IFENSNGNPQ VYGRELGRLL FAETIKNYFK
810 820 830 840 850
DQDADKRQWI HEILDFRFPS KGPLEGKQKW KNVTAAINRN MTAAVVSRRS

LPR
Length:853
Mass (Da):96,405
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8179E143852FE2CC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAA97791.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T20804

NCBI Reference Sequences

More...
RefSeqi
NP_502182.2, NM_069781.6

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F12F6.1.1; F12F6.1.1; WBGene00008720

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
178081

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F12F6.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAA97791.2
PIRiT20804
RefSeqiNP_502182.2, NM_069781.6

3D structure databases

SMRiG5EE62
ModBaseiSearch...

Protein-protein interaction databases

IntActiG5EE62, 1 interactor

Proteomic databases

EPDiG5EE62
PaxDbiG5EE62
PeptideAtlasiG5EE62

Genome annotation databases

EnsemblMetazoaiF12F6.1.1; F12F6.1.1; WBGene00008720
GeneIDi178081
KEGGicel:CELE_F12F6.1

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
178081
WormBaseiF12F6.1 ; CE34803 ; WBGene00008720

Phylogenomic databases

eggNOGiENOG502TH2C, Eukaryota
HOGENOMiCLU_332399_0_0_1
InParanoidiG5EE62
OMAiWIHEILD
OrthoDBi295671at2759

Gene expression databases

BgeeiWBGene00008720, Expressed in multi-cellular organism and 5 other tissues

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG5EE62_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EE62
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 2, 2021
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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