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UniProtKB - G5EDU0 (G5EDU0_CAEEL)
Protein
Submitted name:
MFS domain-containing protein
Gene
oat-1
Organism
Caenorhabditis elegans
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Enzyme and pathway databases
Reactomei | R-CEL-112311, Neurotransmitter clearance R-CEL-181430, Norepinephrine Neurotransmitter Release Cycle R-CEL-197264, Nicotinamide salvaging R-CEL-200425, Carnitine metabolism R-CEL-2161517, Abacavir transmembrane transport R-CEL-442660, Na+/Cl- dependent neurotransmitter transporters R-CEL-549127, Organic cation transport R-CEL-561048, Organic anion transport |
Protein family/group databases
TCDBi | 2.A.1.19.26, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Submitted name: MFS domain-containing proteinImportedSubmitted name: Multispecific organic anion transporterImported |
Gene namesi | Name:oat-1Imported ORF Names:CELE_T01B11.7Imported, T01B11.7Imported |
Organismi | Caenorhabditis elegansImported |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | T01B11.7 ; CE30160 ; WBGene00003837 ; oat-1 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 43 – 71 | HelicalSequence analysisAdd BLAST | 29 | |
Transmembranei | 155 – 173 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 179 – 200 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 212 – 233 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 239 – 257 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 318 – 347 | HelicalSequence analysisAdd BLAST | 30 | |
Transmembranei | 359 – 379 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 391 – 413 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 419 – 441 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 481 – 502 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | WBGene00003837, Expressed in material anatomical entity and 3 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 67 – 506 | MFSInterPro annotationAdd BLAST | 440 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00970000196615 |
HOGENOMi | CLU_001265_33_2_1 |
OMAi | ELRWYCM |
OrthoDBi | 762280at2759 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G5EDU0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSKSSTSSE EDENFIKDVE DQKVLEVLTS HSKFKSLDDL VELRWYCMLV
60 70 80 90 100
LIMAEITAFT ALASVMVMVF AGANPTVVGC DNTVVNGCHE YYSLKNRSGC
110 120 130 140 150
TPVLEYQFES VQVEFNYICD DAKKVKNTIT IQTFGVLVGA AIFGQVSDNF
160 170 180 190 200
GRRKALIISC IGNAIFNLIS SYSPSLFYFM LWRTVSGIFA GGLTVVQMVY
210 220 230 240 250
MVENIPRHHR MWIQNSITWS PNLIIFPYIA YLAQNWRTLS VVISATSVLS
260 270 280 290 300
FLALMLLEES PRWLVQKGKL EEARRLLIKI RKTDGLYTSD FEKDLDEVLK
310 320 330 340 350
IEAEKQVISS KKSKKYTFIH LFCTWKMIAQ TMTFIVGIIC TNFIVYALLY
360 370 380 390 400
NMEKLSGSLY WNSAIIGAAR WVVNIVVSIA DYQLPWFGRR LINHISMIFT
410 420 430 440 450
LASLAIVAGY VYIGNGGYVV AIGTTVALAM CSQLFIAKYL MVNELYPTAV
460 470 480 490 500
RNLAVSAVST MSRVGGMFSP QLFYLSDIAE WIPYAVLVGF QLVDLVLFCI
510 520
TIPETKGVHL ENHLPPEHKR IFGKRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF152095 mRNA Translation: AAF73198.1 BX284604 Genomic DNA Translation: CCD65923.1 |
PIRi | T25852 T25853 |
RefSeqi | NP_501442.2, NM_069041.5 |
Genome annotation databases
EnsemblMetazoai | T01B11.7.1; T01B11.7.1; WBGene00003837 T01B11.7.2; T01B11.7.2; WBGene00003837 |
GeneIDi | 177649 |
KEGGi | cel:CELE_T01B11.7 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF152095 mRNA Translation: AAF73198.1 BX284604 Genomic DNA Translation: CCD65923.1 |
PIRi | T25852 T25853 |
RefSeqi | NP_501442.2, NM_069041.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 6239.T01B11.7.1 |
Protein family/group databases
TCDBi | 2.A.1.19.26, the major facilitator superfamily (mfs) |
Genome annotation databases
EnsemblMetazoai | T01B11.7.1; T01B11.7.1; WBGene00003837 T01B11.7.2; T01B11.7.2; WBGene00003837 |
GeneIDi | 177649 |
KEGGi | cel:CELE_T01B11.7 |
Organism-specific databases
CTDi | 177649 |
WormBasei | T01B11.7 ; CE30160 ; WBGene00003837 ; oat-1 |
Phylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00970000196615 |
HOGENOMi | CLU_001265_33_2_1 |
OMAi | ELRWYCM |
OrthoDBi | 762280at2759 |
Enzyme and pathway databases
Reactomei | R-CEL-112311, Neurotransmitter clearance R-CEL-181430, Norepinephrine Neurotransmitter Release Cycle R-CEL-197264, Nicotinamide salvaging R-CEL-200425, Carnitine metabolism R-CEL-2161517, Abacavir transmembrane transport R-CEL-442660, Na+/Cl- dependent neurotransmitter transporters R-CEL-549127, Organic cation transport R-CEL-561048, Organic anion transport |
Gene expression databases
Bgeei | WBGene00003837, Expressed in material anatomical entity and 3 other tissues |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G5EDU0_CAEEL | |
Accessioni | G5EDU0Primary (citable) accession number: G5EDU0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 14, 2011 |
Last sequence update: | December 14, 2011 | |
Last modified: | January 19, 2022 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |