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Protein
Submitted name:

Variable abnormal-3

Gene

vab-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi217 – 276HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • DNA binding transcription factor activity Source: WormBase
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • anterior/posterior pattern specification Source: WormBase
  • cell fate commitment Source: WormBase
  • nematode male tail tip morphogenesis Source: WormBase
  • positive regulation of transcription by RNA polymerase II Source: WormBase
  • regulation of cell adhesion Source: WormBase
  • regulation of transcription, DNA-templated Source: WormBase
  • transcription, DNA-templated Source: UniProtKB-UniRule

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Variable abnormal-3Imported
Gene namesi
Name:vab-3Imported
ORF Names:CELE_F14F3.1Imported, F14F3.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF14F3.1a ; CE24899 ; WBGene00006870 ; vab-3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiWBGene00006870

Interactioni

Protein-protein interaction databases

IntActiG5EDS1, 85 interactors
STRINGi6239.F14F3.1a

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 131PairedInterPro annotationAdd BLAST127
Domaini215 – 275HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotation, Paired boxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0849 Eukaryota
ENOG410XS01 LUCA
GeneTreeiENSGT00680000099553
KOiK08031
OMAiMSDAGHT
OrthoDBiEOG091G0S4E

Family and domain databases

CDDicd00086 homeodomain, 1 hit
cd00131 PAX, 1 hit
Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR001523 Paired_dom
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00292 PAX, 1 hit
PRINTSiPR00027 PAIREDBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00351 PAX, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00034 PAIRED_1, 1 hit
PS51057 PAIRED_2, 1 hit

Sequencei

Sequence statusi: Complete.

G5EDS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDAGHTGVN QLGGVFVNGR PLPDATRQRI VDLAHKGCRP CDISRLLQVS
60 70 80 90 100
NGCVSKILCR YYESGTIRPR AIGGSKPRVA TSDVVEKIED YKRDQPSIFA
110 120 130 140 150
WEIRDKLLAD NICNNETIPS VSSINRVLRN LAAKKEQVTM QTELYDRIRI
160 170 180 190 200
VDNFPYNSSW YGQWPIPMNG AVGLNPFVPA PLIEPKTEGE FEKDEDQKPP
210 220 230 240 250
TEPEDDAAAR MRLKRKLQRN RTSFTQVQIE SLEKEFERTH YPDVFARERL
260 270 280 290 300
AQKIQLPEAR IQVWFSNRRA KWRREEKMRN KRSSGTMDSS LSNGTPTPTP
310 320 330 340 350
GSVTGSNMTN PIGSPASTPN RFPSNNSANL PTTNFVPQTS QMYAGLSQPA
360 370 380 390 400
MDPYSFGIAN GFSMAPYPQV TDFQPHHMFQ GRSPYDFPYP RMPTNGHGFQ
410 420 430 440 450
QSMSPATTAV GDIPTLSSGM SLPVSAVLNS IDPSLTHSQM HELSDLTQEH

YWRPQ
Length:455
Mass (Da):51,061
Last modified:December 14, 2011 - v1
Checksum:i70D75A22A6739C57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31537 mRNA Translation: AAA82991.1
BX284606 Genomic DNA Translation: CAA90186.2
PIRiT20900 S60252
RefSeqiNP_001024570.1, NM_001029399.2
UniGeneiCel.8982

Genome annotation databases

EnsemblMetazoaiF14F3.1a; F14F3.1a; WBGene00006870
GeneIDi181251
KEGGicel:CELE_F14F3.1

Similar proteinsi

Entry informationi

Entry nameiG5EDS1_CAEEL
AccessioniPrimary (citable) accession number: G5EDS1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 18, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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