Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

EPS (Human endocytosis) related

Gene

eps-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin filament binding Source: WormBase
  • cytoskeletal protein binding Source: WormBase

GO - Biological processi

  • actin filament bundle assembly Source: WormBase
  • barbed-end actin filament capping Source: WormBase
  • digestive tract morphogenesis Source: WormBase
  • embryonic morphogenesis Source: WormBase
  • epidermis morphogenesis Source: WormBase
  • intermediate filament organization Source: WormBase
  • maintenance of protein location Source: WormBase
  • nematode larval development Source: WormBase

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
EPS (Human endocytosis) relatedImported
Submitted name:
Epidermal growth factor receptor pathway substrate 8 splice variant AImported
Gene namesi
Name:eps-8Imported
ORF Names:CELE_Y57G11C.24Imported, Y57G11C.24Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY57G11C.24g ; CE39450 ; WBGene00001330 ; eps-8

Subcellular locationi

Expressioni

Gene expression databases

BgeeiWBGene00001330

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • actin filament binding Source: WormBase
  • cytoskeletal protein binding Source: WormBase

Protein-protein interaction databases

STRINGi6239.Y57G11C.24g

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini604 – 663SH3InterPro annotationAdd BLAST60

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili295 – 315Sequence analysisAdd BLAST21
Coiled coili495 – 539Sequence analysisAdd BLAST45

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3557 Eukaryota
ENOG410XT9R LUCA
GeneTreeiENSGT00390000003646

Family and domain databases

CDDicd01210 PTB_EPS8, 1 hit
cd11764 SH3_Eps8, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR033928 EPS8_PTB
IPR035462 Eps8_SH3
IPR011993 PH-like_dom_sf
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR013761 SAM/pointed_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF08416 PTB, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

G5ED33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRGGSMGPP SGDPYQSRPS PGGYYYNRST PGGQPAPSPS HSQQSASSHH
60 70 80 90 100
PRGVPMSQPI ARRSDYRTGS EQMTPRSDHR GPSMGYGNGG SVDQRVDDVT
110 120 130 140 150
PSYYVEHLAT FAVGRQFGLT FPADGIRKLK QMEKNSAIWA QPLILRFRHN
160 170 180 190 200
AVTVEDDNGE LVEQFPLELI EQPTAHVSND SRETYNNVLL FVVREDRKRM
210 220 230 240 250
STPTEMHIFQ CIRVSATDVA EDLKNYVQGQ FRRVRNGRRT AAPTHLQAQQ
260 270 280 290 300
QQMPFYPPDD ASISSETSEM FERDVNTLNR CFDDIERFVA RIQSAALAQR
310 320 330 340 350
EIEQQNHRYR TANRRDKKNQ QPPDPNGILF MRAQLPLESE FVDILKKFKL
360 370 380 390 400
SFNLLAKLKN HIHEPNAPEL LHFLFTPLAV ILEACHWGLG RNVAPTVASP
410 420 430 440 450
LLSLEARELM QNCLTSHESD IWMSLGEAWR TPPEDWTKPL PPPYRPIFND
460 470 480 490 500
GFAPYGVADR AMATPNQIHR GHSAPPEHFR QPPPRERNMV DTLEFDRLTL
510 520 530 540 550
ERERLEFEKA KIMERESRLR HEEKQIEDEK RRMHAEKDLI TKETTQPVPP
560 570 580 590 600
PAAVVTHQPI TKRYDPPISI SPPPQRNNYS HVKVTVDSDT SPRQQAFIDD
610 620 630 640 650
IVAKGGKLAV VTYDRGGQNT KELTVHKGEY LEVIFDERNW WECKNMHQRV
660 670 680 690 700
GYVPHTILSM VPFEQQQYAS PNHHNNSSST GGYNNGHHQG PAQNVYRPPP
710 720 730 740 750
PPLVSDAGVQ VEIRREHVAP PPPPVVIPPP PPPVRTPTME ELLRMQQQQQ
760 770 780 790 800
QKQRKPPVEE PVYQPQPAQR AGLEIWRRNQ NPQLIQEVTE TVGQHSGDIL
810 820 830 840 850
RPAMQRATRV AINEKSSPED VTRWLQEKGF SPRVIDLLDG QDGANLFSLS
860 870 880 890 900
KLHLQQACGR DEGGYLYSQL LVQKKRSGFR THTGDELKAI LNHRRTHVEL
910
SNEAAADEPV FTINPIL
Length:917
Mass (Da):104,365
Last modified:December 14, 2011 - v1
Checksum:i4BC021037B43E170
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY611484 mRNA Translation: AAT37523.1
BX284604 Genomic DNA Translation: CAJ44243.1
RefSeqiNP_001041047.1, NM_001047582.3
UniGeneiCel.17206

Genome annotation databases

EnsemblMetazoaiY57G11C.24g; Y57G11C.24g; WBGene00001330
GeneIDi178411

Similar proteinsi

Entry informationi

Entry nameiG5ED33_CAEEL
AccessioniPrimary (citable) accession number: G5ED33
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 20, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health