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Protein
Submitted name:

NeuroPeptide Receptor family

Gene

npr-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NeuroPeptide Receptor familyImported
Gene namesi
Name:npr-2Imported
ORF Names:CELE_T05A1.1Imported, T05A1.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT05A1.1a ; CE32924 ; WBGene00003808 ; npr-2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei68 – 94HelicalSequence analysisAdd BLAST27
Transmembranei106 – 132HelicalSequence analysisAdd BLAST27
Transmembranei144 – 165HelicalSequence analysisAdd BLAST22
Transmembranei186 – 204HelicalSequence analysisAdd BLAST19
Transmembranei232 – 256HelicalSequence analysisAdd BLAST25
Transmembranei319 – 341HelicalSequence analysisAdd BLAST23
Transmembranei361 – 386HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiG5ED22

Expressioni

Gene expression databases

BgeeiWBGene00003808
ExpressionAtlasiG5ED22 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.T05A1.1a

Structurei

3D structure databases

ProteinModelPortaliG5ED22
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 383G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST298

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili260 – 280Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00920000148949
InParanoidiG5ED22
OMAiPFATMAF
OrthoDBiEOG091G06MF
PhylomeDBiG5ED22

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000611 NPY_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01012 NRPEPTIDEYR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

G5ED22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMVNTRVEA PDLLALKNML RQSDGTRMLQ EMRRKLIQLH SSQMINETEE
60 70 80 90 100
TCDRYIDKHP DMTNEPTVLV TFSLLYLHIF LLGILGNSAV LYLTMKHRQL
110 120 130 140 150
QTVQNIFILN LCASNVLMCL TSLPITFITN VYKQWFFSSP VCKLIPLVQG
160 170 180 190 200
ASIFVSTFSL SAIALDRYNL VVRPHKQKLS SRSAMMIALL IWVISVVVCM
210 220 230 240 250
PYGWYMDVEK LNGLCGEYCS EHWPLAEVRK GYTFLVLITQ FLFPFATMAF
260 270 280 290 300
CYYNIFSRLR QRVETKLKKL SERSQLLENS TTCGTTNHIV SINAEAVQNG
310 320 330 340 350
LENKQRLAVL AQQRRTTTIL SCMVLLFAFT WLPHNVVTLM IEYDGFFFHS
360 370 380 390 400
DETSATSTDH TYIVSMTAHL ISMLTNVTNP FLYAWLNPMF KEMLIKTLRG
410 420 430
GSKSPKPADI KQTSFIRMPN SGAPSQSSYL
Length:430
Mass (Da):49,138
Last modified:December 14, 2011 - v1
Checksum:i4B0E8890C94CB9E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAD59155.1
RefSeqiNP_501701.2, NM_069300.4
UniGeneiCel.12399

Genome annotation databases

EnsemblMetazoaiT05A1.1a; T05A1.1a; WBGene00003808
GeneIDi177790
KEGGicel:CELE_T05A1.1

Similar proteinsi

Entry informationi

Entry nameiG5ED22_CAEEL
AccessioniPrimary (citable) accession number: G5ED22
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 20, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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