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Entry version 69 (23 Feb 2022)
Sequence version 1 (14 Dec 2011)
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Protein

Latrophilin-like protein LAT-2

Gene

lat-2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May have a role in pharyngeal pumping during feeding.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
LigandLectin

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-373080, Class B/2 (Secretin family receptors)
R-CEL-6798695, Neutrophil degranulation

Protein family/group databases

MEROPS protease database

More...
MEROPSi
S01.A54

Transport Classification Database

More...
TCDBi
9.A.14.6.5, the g-protein-coupled receptor (gpcr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Latrophilin-like protein LAT-2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lat-2Imported
ORF Names:B0286.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
B0286.2a ; CE36968 ; WBGene00002252 ; lat-2
B0286.2b ; CE39661 ; WBGene00002252 ; lat-2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini20 – 901ExtracellularSequence analysisAdd BLAST882
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei902 – 922Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini923 – 930CytoplasmicSequence analysis8
Transmembranei931 – 951Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini952 – 959ExtracellularSequence analysis8
Transmembranei960 – 980Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini981 – 999CytoplasmicSequence analysisAdd BLAST19
Transmembranei1000 – 1020Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini1021 – 1040ExtracellularSequence analysisAdd BLAST20
Transmembranei1041 – 1061Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini1062 – 1085CytoplasmicSequence analysisAdd BLAST24
Transmembranei1086 – 1106Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini1107 – 1115ExtracellularSequence analysis9
Transmembranei1116 – 1136Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini1137 – 1338CytoplasmicSequence analysisAdd BLAST202

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Reduced response to the inhibitory action of emodepside in pharyngeal pumping.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000042217720 – 1338Latrophilin-like protein LAT-2Sequence analysisAdd BLAST1319

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi29 ↔ 40Sequence analysis
Disulfide bondi52 ↔ 63Sequence analysis
Disulfide bondi80 ↔ 192Sequence analysis
Disulfide bondi167 ↔ 184Sequence analysis
Disulfide bondi209 ↔ 218Sequence analysis

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
G5ECX0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Pharyngeal primordium.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00002252, Expressed in multi-cellular organism and 3 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
39127, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.B0286.2a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
G5ECX0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 64EGF-like 1PROSITE-ProRule annotationAdd BLAST40
Domaini59 – 193C-type lectinPROSITE-ProRule annotationAdd BLAST135
Domaini180 – 219EGF-like 2PROSITE-ProRule annotationAdd BLAST40
Domaini233 – 322SUEL-type lectinPROSITE-ProRule annotationAdd BLAST90
Domaini838 – 885GPSPROSITE-ProRule annotationAdd BLAST48

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1300 – 1338DisorderedSequence analysisAdd BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.Sequence analysis

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4193, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166745

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_270428_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G5ECX0

Identification of Orthologs from Complete Genome Data

More...
OMAi
NCTHRWV

Database of Orthologous Groups

More...
OrthoDBi
388923at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
G5ECX0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.740, 1 hit
3.10.100.10, 2 hits
4.10.1240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001304, C-type_lectin-like
IPR016186, C-type_lectin-like/link_sf
IPR016187, CTDL_fold
IPR000742, EGF-like_dom
IPR032471, GAIN_dom_N
IPR017981, GPCR_2-like
IPR036445, GPCR_2_extracell_dom_sf
IPR001879, GPCR_2_extracellular_dom
IPR000832, GPCR_2_secretin-like
IPR000203, GPS
IPR000922, Lectin_gal-bd_dom
IPR043159, Lectin_gal-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002, 7tm_2, 1 hit
PF16489, GAIN, 1 hit
PF02140, Gal_Lectin, 1 hit
PF01825, GPS, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00249, GPCRSECRETIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00034, CLECT, 2 hits
SM00303, GPS, 1 hit
SM00008, HormR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56436, SSF56436, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50041, C_TYPE_LECTIN_2, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 2 hits
PS50227, G_PROTEIN_RECEP_F2_3, 1 hit
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit
PS50228, SUEL_LECTIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform a2 Publications (identifier: G5ECX0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAKQLKYPFL IFIISLAQCQ VSNQNVNLCQ SNICQNGGTC LVASSVPATA
60 70 80 90 100
TCPKNSIYYM GSCYVFDTTL RNWNDAALYC NNMNSATLPL VESAEDQAFF
110 120 130 140 150
AGYLQAMIPS NPPADMRPPP DGIWTAVRGV NNVTRASWVY YPGSFLVTDT
160 170 180 190 200
FWAPQEPNIY VNYNDVCVAL QSDSFYREWT TALCTILKYT VCKVAPTQIQ
210 220 230 240 250
AKYVAQCSCP NGYGGQTCET QSTTNQQAST QRTCGSNDFQ FSCPNDQTIT
260 270 280 290 300
VDFASFGAQE SSMCNQASQS REQTCSNVNS LQTVINACQG LQSCEIRNLT
310 320 330 340 350
STFSNTPCPV PQEQYLETRM RCETAQQPSC LSGLIQFDSR CYSMTIETNE
360 370 380 390 400
KKQRTMEDAQ TYCSQSGGSI ITSPPDALLQ QIVQKVNAET KKTVNFWIGT
410 420 430 440 450
PNNCQLLMVT GSSTSYSQCP SSPSSTANVI CSTVPQSTAS VSARPTQSAP
460 470 480 490 500
VDPVSQTMAR REVYTGVQPP SVPDSINKPR YCKKEKKDGI TYEQTRACML
510 520 530 540 550
HEQPCPDPQN VEGTVTRYCN CQTAKWETPD TTNCTHRWVA EMETAIKDNQ
560 570 580 590 600
PVEDISSTVN RQLKSTIERT LFGGDITGTV RLSNDMLSLA RNQFSVLNDR
610 620 630 640 650
NLRENKARNF TENLGGSGDQ LLSPVAATVW DQLSSTIRIQ HASKLMSVLE
660 670 680 690 700
QSVLLLGDYM TDQKLNLQYI NWAMEVERSE PEVQTFGAAA SPNVQDDMGM
710 720 730 740 750
MRVMAAAPPA PQPETNTTIM FPSLKLSPTI TLPSASLLSS LASPTPVAGG
760 770 780 790 800
GPSILSSFQD DTPVGMASTP NLNRNPVKLG YYAFAGFGQL LNNNNDHTLI
810 820 830 840 850
NSQVIGASIQ NATQSVTLPV DHPVTFTFQH LTTKGVSNPR CVYWDLMESK
860 870 880 890 900
WSTLGCTLIA TSSNSSQCSC THLTSFAILM DISGQVGRLS GGLASALDVV
910 920 930 940 950
STIGCAISIV CLALSVCVFT FFRNLQNVRN SIHRNLCLCL LIAELVFVIG
960 970 980 990 1000
MDRTGNRTGC GVVAILLHYF FLSSFCWMLL EGYQLYMMLI QVFEPNRTRI
1010 1020 1030 1040 1050
FLYYLFCYGT PAVVVAISAG IKWEDYGTDS YCWIDTSTPT IWAFVAPIIV
1060 1070 1080 1090 1100
IIAANIIFLL IALKVVLSVQ SRDRTKWGRI IGWLKGSATL LCLLGITWIF
1110 1120 1130 1140 1150
GFLTAVKGGT GTAFAWIFTI LNCTQGIFIF VLHVVLNEKV RASIVRWLRT
1160 1170 1180 1190 1200
GICCLPETSS AAYNSRSFLS SRQRILNMIK VNGHSYPSTA STDDKEKQLT
1210 1220 1230 1240 1250
PITKTTDWLS RLPNQDSVSI PESNFNNLNG TLENSNLNSA EIKEEDEIPE
1260 1270 1280 1290 1300
LRRRVTVDLN PMIVSNNEIE RMSHASSDPR GSQIIEVTAV EKKAPVKRIK
1310 1320 1330
FPLGAKQSER GSQHRTKAKV IAPPESPVSE SGSKDYRF
Length:1,338
Mass (Da):147,302
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i43B63CFE3FD47BC6
GO
Isoform b1 Publication (identifier: G5ECX0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-879: Missing.

Show »
Length:459
Mass (Da):51,075
Checksum:iA9E33B19EA69DA38
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0464861 – 879Missing in isoform b. 1 PublicationAdd BLAST879

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY314772 mRNA Translation: AAQ84879.1
FO080154 Genomic DNA Translation: CCD61661.1
FO080154 Genomic DNA Translation: CCD61662.1

NCBI Reference Sequences

More...
RefSeqi
NP_001040724.1, NM_001047259.2 [G5ECX0-1]
NP_001040725.1, NM_001047260.1 [G5ECX0-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
B0286.2a.1; B0286.2a.1; WBGene00002252 [G5ECX0-1]
B0286.2b.1; B0286.2b.1; WBGene00002252 [G5ECX0-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
173771

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_B0286.2

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY314772 mRNA Translation: AAQ84879.1
FO080154 Genomic DNA Translation: CCD61661.1
FO080154 Genomic DNA Translation: CCD61662.1
RefSeqiNP_001040724.1, NM_001047259.2 [G5ECX0-1]
NP_001040725.1, NM_001047260.1 [G5ECX0-2]

3D structure databases

SMRiG5ECX0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi39127, 1 interactor
STRINGi6239.B0286.2a

Protein family/group databases

MEROPSiS01.A54
TCDBi9.A.14.6.5, the g-protein-coupled receptor (gpcr) family

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

Proteomic databases

PaxDbiG5ECX0

Genome annotation databases

EnsemblMetazoaiB0286.2a.1; B0286.2a.1; WBGene00002252 [G5ECX0-1]
B0286.2b.1; B0286.2b.1; WBGene00002252 [G5ECX0-2]
GeneIDi173771
KEGGicel:CELE_B0286.2

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
173771
WormBaseiB0286.2a ; CE36968 ; WBGene00002252 ; lat-2
B0286.2b ; CE39661 ; WBGene00002252 ; lat-2

Phylogenomic databases

eggNOGiKOG4193, Eukaryota
GeneTreeiENSGT00940000166745
HOGENOMiCLU_270428_0_0_1
InParanoidiG5ECX0
OMAiNCTHRWV
OrthoDBi388923at2759
PhylomeDBiG5ECX0

Enzyme and pathway databases

ReactomeiR-CEL-373080, Class B/2 (Secretin family receptors)
R-CEL-6798695, Neutrophil degranulation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:G5ECX0

Gene expression databases

BgeeiWBGene00002252, Expressed in multi-cellular organism and 3 other tissues

Family and domain databases

Gene3Di2.60.120.740, 1 hit
3.10.100.10, 2 hits
4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR001304, C-type_lectin-like
IPR016186, C-type_lectin-like/link_sf
IPR016187, CTDL_fold
IPR000742, EGF-like_dom
IPR032471, GAIN_dom_N
IPR017981, GPCR_2-like
IPR036445, GPCR_2_extracell_dom_sf
IPR001879, GPCR_2_extracellular_dom
IPR000832, GPCR_2_secretin-like
IPR000203, GPS
IPR000922, Lectin_gal-bd_dom
IPR043159, Lectin_gal-bd_sf
PfamiView protein in Pfam
PF00002, 7tm_2, 1 hit
PF16489, GAIN, 1 hit
PF02140, Gal_Lectin, 1 hit
PF01825, GPS, 1 hit
PRINTSiPR00249, GPCRSECRETIN
SMARTiView protein in SMART
SM00034, CLECT, 2 hits
SM00303, GPS, 1 hit
SM00008, HormR, 1 hit
SUPFAMiSSF56436, SSF56436, 2 hits
PROSITEiView protein in PROSITE
PS50041, C_TYPE_LECTIN_2, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 2 hits
PS50227, G_PROTEIN_RECEP_F2_3, 1 hit
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit
PS50228, SUEL_LECTIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLPLT2_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5ECX0
Secondary accession number(s): B2MZA8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: December 14, 2011
Last modified: February 23, 2022
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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