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Entry version 45 (08 May 2019)
Sequence version 1 (14 Dec 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

ANIA_03729

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • 1,3-beta-D-glucan synthase activity Source: AspGD

GO - Biological processi

  • (1->3)-beta-D-glucan biosynthetic process Source: AspGD
  • glucan biosynthetic process Source: AspGD

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT48 Glycosyltransferase Family 48

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ANIA_03729Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri227321 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000560 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei484 – 503HelicalSequence analysisAdd BLAST20
Transmembranei523 – 545HelicalSequence analysisAdd BLAST23
Transmembranei565 – 588HelicalSequence analysisAdd BLAST24
Transmembranei594 – 620HelicalSequence analysisAdd BLAST27
Transmembranei653 – 675HelicalSequence analysisAdd BLAST23
Transmembranei1330 – 1349HelicalSequence analysisAdd BLAST20
Transmembranei1382 – 1403HelicalSequence analysisAdd BLAST22
Transmembranei1473 – 1490HelicalSequence analysisAdd BLAST18
Transmembranei1496 – 1517HelicalSequence analysisAdd BLAST22
Transmembranei1588 – 1610HelicalSequence analysisAdd BLAST23
Transmembranei1630 – 1657HelicalSequence analysisAdd BLAST28
Transmembranei1669 – 1695HelicalSequence analysisAdd BLAST27
Transmembranei1707 – 1726HelicalSequence analysisAdd BLAST20
Transmembranei1830 – 1850HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
162425.CADANIAP00004994

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000216604

KEGG Orthology (KO)

More...
KOi
K00706

Identification of Orthologs from Complete Genome Data

More...
OMAi
AEWAYVP

Database of Orthologous Groups

More...
OrthoDBi
48442at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026899 FKS1-like_dom1
IPR003440 Glyco_trans_48

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14288 FKS1_dom1, 1 hit
PF02364 Glucan_synthase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01205 FKS1_dom1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G5EB86-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGYPQGSGY QHGNYDDGYD HQGHGDAYYQ DDHHAQAGYY DNQDYGDGYY
60 70 80 90 100
DRGGYGDHGY QHDGYYDAGH HDDYYGDQYY AQGGQGRGRH GRDSEEESET
110 120 130 140 150
FSDFTMRSET ARAADMDYYG RGDERYNSYT DSQYGHGGYG YRPPSSQVSY
160 170 180 190 200
GGNRSSGAST PVYGMDYGNG LPAGQRSREP YPAWASDGQV PVSKEEIEDI
210 220 230 240 250
FIDLVNKFGF QRDSMRNMYD HLMTQLDSRA SRMTPNQALL SLHADYIGGD
260 270 280 290 300
NANYRRWYFA AHLDLDDAVG FANMKLGKAD RKTRKARKAA KKKAQENPED
310 320 330 340 350
VEGTLEALEG DNSLEAAEYR WKTRMNRMSQ HERVRQLALY LLCWGEANQV
360 370 380 390 400
RFLPEALCFI FKCADDFYNS PECQNRVEPV EEFTYLNEII TPLYQYCRDQ
410 420 430 440 450
GYEILDGKYV RRERDHNQII GYDDMNQLFW YPEGIERIVL EDKTRLVDIP
460 470 480 490 500
TAERWTKLKE VNWKKVFFKT YKETRSWFHL VTNFNRIWVI HLGAFWFFTA
510 520 530 540 550
YNAPTIYTKN YRQQLNNKPP GAYYWSAVGF GGALVSFIQI MATIFEWMYV
560 570 580 590 600
PRRWAGAQHL TKRLLFLLLV FVINLAPGVV VFGFSSVLPG KVPLVVGIVH
610 620 630 640 650
FFIALATFFF FSIMPLGGLF GSYLKKHGRQ YVASQTFTAS FPRLKGNDMW
660 670 680 690 700
MSYGLWVCVF GAKLAESYFF LTLSIKDPIR YLSPYHVHQC AGVKYIGDKI
710 720 730 740 750
CYYQPQILLG LMFFMDLTLF FLDSYLWYII CNTIFSVARS FYLGVSIWSP
760 770 780 790 800
WRNIFSRLPK RIYSKVLATT DMEIKYKPKV LISQVWNAII ISMYREHLLA
810 820 830 840 850
IDHVQKLLYH QVPSEQEGKR TLRAPTFFVS QEDQSFKTEF FPRGSEAERR
860 870 880 890 900
ISFFAQSLST PMPEPLPVDN MPTFTVLIPH YSEKILLSLR EIIREDEPYS
910 920 930 940 950
RVTLLEYLKQ LHPHEWDCFV KDTKILADET SQFNGDYEKN EKDAAKSKID
960 970 980 990 1000
DLPFYCIGFK SAAPEYTLRT RIWSSLRSQT LYRTVSGMMN YSRAIKLLYR
1010 1020 1030 1040 1050
VENPEVVQMF GGNSEKLEHE LERMARRKFK ICVSMQRYAK FTKEERENTE
1060 1070 1080 1090 1100
FLLRAYPDLQ IAYLDEEPPA NEGEEPRLYS ALIDGHCELL ENGMRKPKFR
1110 1120 1130 1140 1150
IQLSGNPILG DGKSDNQNHS IIFYRGEYIQ VIDANQDNYL EECLKIRSVL
1160 1170 1180 1190 1200
AEFEELTTDN VSPYTPGVAS SSEAPVAILG AREYIFSENI GVLGDVAAGK
1210 1220 1230 1240 1250
EQTFGTLFAR TLAQIGGKLH YGHPDFLNGI FMTTRGGISK AQKGLHLNED
1260 1270 1280 1290 1300
IYAGMNAMVR GGRIKHCEYF QCGKGRDLGF GSILNFTTKI GTGMGEQMLS
1310 1320 1330 1340 1350
REYYYLGTQL PLDRFLSFYY AHPGFHINNM FIMLSVQMFM IVLINLGALK
1360 1370 1380 1390 1400
HETINCNYNS DLPITDPLMP TFCAPLTPII NWVNRCVISI FIVFFISFVP
1410 1420 1430 1440 1450
LAVQELTERG LWRMATRLAK HFGSFSFMFE VFVCQIYSNA VHQNLSFGGA
1460 1470 1480 1490 1500
RYIATGRGFA TARIPFGVLY SRFAGPSIYT GFRLLIMLLF STSTTWTASL
1510 1520 1530 1540 1550
IWFWVSLLAL CISPFLFNPH QFAWNDFFID YRDYIRWLSR GNSRSHASSW
1560 1570 1580 1590 1600
IGFCRLSRTR ITGYKRKLLG VPSEKGSGDV PRARITNIFF SEIVAPLVLV
1610 1620 1630 1640 1650
AVTLVPYLYI NSRTGVSADV DGGNDPHDAI LRIAIVAFGP IGINAGVAAV
1660 1670 1680 1690 1700
FFGMACCMGP ILSMCCKKFG AVLAAIAHAI AVIILLVIFE VMFFLEHWSW
1710 1720 1730 1740 1750
PRCVMGMIAM AAIQRFVYKL IIALALTREF KHDQSNIAWW TGKWYNMGWH
1760 1770 1780 1790 1800
SLSQPGREFL CKITELGYFS ADFVIGHLLL FIMLPALCVP YIDKFHSVIL
1810 1820 1830 1840 1850
FWLRPSRQIR PPIYSLKQSK LRKRRVVRFA ILYFAMLILF LVLLIAPLIA
1860 1870 1880 1890 1900
RNQDLNLKMS GILLELMQPL DSNNNDTMTS YTGSGVPKGM EPIASPSSYL

TNLNN
Length:1,905
Mass (Da):218,474
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF921DA02B03446C0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BN001302 Genomic DNA Translation: CBF75516.1

NCBI Reference Sequences

More...
RefSeqi
XP_661333.1, XM_656241.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CBF75516; CBF75516; ANIA_03729
EAA59937; EAA59937; AN3729.2

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2873152

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ani:AN3729.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001302 Genomic DNA Translation: CBF75516.1
RefSeqiXP_661333.1, XM_656241.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi162425.CADANIAP00004994

Protein family/group databases

CAZyiGT48 Glycosyltransferase Family 48

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCBF75516; CBF75516; ANIA_03729
EAA59937; EAA59937; AN3729.2
GeneIDi2873152
KEGGiani:AN3729.2

Phylogenomic databases

HOGENOMiHOG000216604
KOiK00706
OMAiAEWAYVP
OrthoDBi48442at2759

Family and domain databases

InterProiView protein in InterPro
IPR026899 FKS1-like_dom1
IPR003440 Glyco_trans_48
PfamiView protein in Pfam
PF14288 FKS1_dom1, 1 hit
PF02364 Glucan_synthase, 1 hit
SMARTiView protein in SMART
SM01205 FKS1_dom1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG5EB86_EMENI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EB86
Secondary accession number(s): C8V7C0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: May 8, 2019
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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