UniProtKB - G5EA09 (G5EA09_HUMAN)
Protein
Submitted name:
Syndecan binding protein (Syntenin), isoform CRA_a
Gene
SDCBP
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cell adhesion molecule binding Source: Ensembl
- ephrin receptor binding Source: Ensembl
- growth factor binding Source: Ensembl
- identical protein binding Source: Ensembl
- interleukin-5 receptor binding Source: Ensembl
- neurexin family protein binding Source: Ensembl
- protein-containing complex binding Source: Ensembl
- protein C-terminus binding Source: Ensembl
- syndecan binding Source: Ensembl
GO - Biological processi
- actin cytoskeleton organization Source: InterPro
- chemical synaptic transmission Source: InterPro
- positive regulation of cell growth Source: Ensembl
- positive regulation of cell migration Source: Ensembl
- positive regulation of cell population proliferation Source: Ensembl
- presynapse assembly Source: Ensembl
- Ras protein signal transduction Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Syndecan binding protein (Syntenin), isoform CRA_aImportedSubmitted name: Syntenin-1Imported |
Gene namesi | Name:SDCBPImported ORF Names:hCG_1787561Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10662, SDCBP |
VEuPathDBi | HostDB:ENSG00000137575.11 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nuclear membrane Source: HPA
- nucleoplasm Source: HPA
Plasma Membrane
- interleukin-5 receptor complex Source: Ensembl
Other locations
- synapse Source: GOC
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 277 – 299 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000137575, Expressed in substantia nigra and 249 other tissues |
ExpressionAtlasi | G5EA09, baseline and differential |
Interactioni
GO - Molecular functioni
- cell adhesion molecule binding Source: Ensembl
- ephrin receptor binding Source: Ensembl
- growth factor binding Source: Ensembl
- identical protein binding Source: Ensembl
- interleukin-5 receptor binding Source: Ensembl
- neurexin family protein binding Source: Ensembl
- protein C-terminus binding Source: Ensembl
- syndecan binding Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 134 – 213 | PDZInterPro annotationAdd BLAST | 80 | |
Domaini | 218 – 293 | PDZInterPro annotationAdd BLAST | 76 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000154502 |
OMAi | IIRDRPF |
OrthoDBi | 1035679at2759 |
Family and domain databases
Gene3Di | 2.30.42.10, 2 hits |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR030528, SDCBP |
PANTHERi | PTHR12345:SF10, PTHR12345:SF10, 1 hit |
Pfami | View protein in Pfam PF00595, PDZ, 2 hits |
SMARTi | View protein in SMART SM00228, PDZ, 2 hits |
SUPFAMi | SSF50156, SSF50156, 2 hits |
PROSITEi | View protein in PROSITE PS50106, PDZ, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
G5EA09-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKLWTNRDL HIIVMVKNPA KMSLYPSLED LKVDKVIQAQ TAFSANPANP
60 70 80 90 100
AILSEASAPI PHDGNLYPRL YPELSQYMGL SLNEEEIRAN VAVVSGAPLQ
110 120 130 140 150
GLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK
160 170 180 190 200
SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ
210 220 230 240 250
AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN
260 270 280 290 300
GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK
310
RMAPSIMKSL MDHTIPEV
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO00560 | SDCB1_HUMAN | Syntenin-1 | SDCBP MDA9, SYCL | 298 | Annotation score: | ||
B4DHN5 | B4DHN5_HUMAN | Syntenin-1 | SDCBP | 239 | Annotation score: | ||
E9PBU7 | E9PBU7_HUMAN | Syntenin-1 | SDCBP | 244 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068522 Genomic DNA No translation available. CH471068 Genomic DNA Translation: EAW86812.1 |
RefSeqi | NP_001317466.1, NM_001330537.1 |
Genome annotation databases
Ensembli | ENST00000523483; ENSP00000428184; ENSG00000137575 ENST00000630925; ENSP00000487245; ENSG00000137575 |
GeneIDi | 6386 |
UCSCi | uc064nbf.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068522 Genomic DNA No translation available. CH471068 Genomic DNA Translation: EAW86812.1 |
RefSeqi | NP_001317466.1, NM_001330537.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | G5EA09 |
PRIDEi | G5EA09 |
ProteomicsDBi | 34105 |
Protocols and materials databases
Antibodypediai | 3216, 518 antibodies |
DNASUi | 6386 |
Genome annotation databases
Ensembli | ENST00000523483; ENSP00000428184; ENSG00000137575 ENST00000630925; ENSP00000487245; ENSG00000137575 |
GeneIDi | 6386 |
UCSCi | uc064nbf.1, human |
Organism-specific databases
CTDi | 6386 |
HGNCi | HGNC:10662, SDCBP |
OpenTargetsi | ENSG00000137575 |
VEuPathDBi | HostDB:ENSG00000137575.11 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154502 |
OMAi | IIRDRPF |
OrthoDBi | 1035679at2759 |
Miscellaneous databases
BioGRID-ORCSi | 6386, 11 hits in 996 CRISPR screens |
ChiTaRSi | SDCBP, human |
GenomeRNAii | 6386 |
Gene expression databases
Bgeei | ENSG00000137575, Expressed in substantia nigra and 249 other tissues |
ExpressionAtlasi | G5EA09, baseline and differential |
Family and domain databases
Gene3Di | 2.30.42.10, 2 hits |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR030528, SDCBP |
PANTHERi | PTHR12345:SF10, PTHR12345:SF10, 1 hit |
Pfami | View protein in Pfam PF00595, PDZ, 2 hits |
SMARTi | View protein in SMART SM00228, PDZ, 2 hits |
SUPFAMi | SSF50156, SSF50156, 2 hits |
PROSITEi | View protein in PROSITE PS50106, PDZ, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G5EA09_HUMAN | |
Accessioni | G5EA09Primary (citable) accession number: G5EA09 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 14, 2011 |
Last sequence update: | December 14, 2011 | |
Last modified: | April 7, 2021 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |