UniProtKB - G5E8K5 (ANK3_MOUSE)
Ankyrin-3
Ank3
Functioni
GO - Molecular functioni
- cadherin binding Source: BHF-UCL
- cytoskeletal protein binding Source: BHF-UCL
- ion channel binding Source: UniProtKB
- phosphorylation-dependent protein binding Source: MGI
- protein-macromolecule adaptor activity Source: BHF-UCL
- spectrin binding Source: BHF-UCL
- structural constituent of cytoskeleton Source: MGI
GO - Biological processi
- axon guidance Source: MGI
- axonogenesis Source: BHF-UCL
- cellular response to magnesium ion Source: UniProtKB
- clustering of voltage-gated sodium channels Source: MGI
- establishment of protein localization Source: MGI
- Golgi to plasma membrane protein transport Source: MGI
- magnesium ion homeostasis Source: UniProtKB
- maintenance of protein location in plasma membrane Source: MGI
- membrane assembly Source: BHF-UCL
- mitotic cytokinesis Source: MGI
- negative regulation of delayed rectifier potassium channel activity Source: UniProtKB
- neuromuscular junction development Source: BHF-UCL
- neuronal action potential Source: BHF-UCL
- plasma membrane organization Source: MGI
- positive regulation of action potential Source: BHF-UCL
- positive regulation of cation channel activity Source: BHF-UCL
- positive regulation of cell communication by electrical coupling Source: BHF-UCL
- positive regulation of gene expression Source: BHF-UCL
- positive regulation of homotypic cell-cell adhesion Source: BHF-UCL
- positive regulation of membrane depolarization during cardiac muscle cell action potential Source: BHF-UCL
- positive regulation of membrane potential Source: BHF-UCL
- positive regulation of protein targeting to membrane Source: BHF-UCL
- positive regulation of sodium ion transmembrane transporter activity Source: BHF-UCL
- positive regulation of sodium ion transport Source: BHF-UCL
- protein localization to axon Source: MGI
- protein localization to plasma membrane Source: BHF-UCL
- regulation of potassium ion transport Source: BHF-UCL
- signal transduction Source: InterPro
- synapse organization Source: MGI
Names & Taxonomyi
Protein namesi | Recommended name: Ankyrin-3Short name: ANK-3 Alternative name(s): Ankyrin-G |
Gene namesi | Name:Ank3 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:88026, Ank3 |
Subcellular locationi
Cytoskeleton
- cytoskeleton By similarity
Lysosome
- Lysosome 1 Publication
Plasma membrane
- sarcolemma By similarity
- postsynaptic cell membrane By similarity
- T-tubule By similarity
Other locations
- axon By similarity
Note: In skeletal muscle, localized at costameres and neuromuscular junctions. In bone marrow-derived macrophages, isoforms 2 and 3 are associated with lysosomes.
Cytoskeleton
- spectrin-associated cytoskeleton Source: BHF-UCL
Endoplasmic reticulum
- sarcoplasmic reticulum Source: BHF-UCL
Lysosome
- lysosome Source: UniProtKB-SubCell
Plasma Membrane
- basal plasma membrane Source: MGI
- basolateral plasma membrane Source: MGI
- lateral plasma membrane Source: MGI
- plasma membrane Source: BHF-UCL
- postsynaptic membrane Source: BHF-UCL
- sarcolemma Source: BHF-UCL
- T-tubule Source: BHF-UCL
Other locations
- axon Source: MGI
- axon initial segment Source: BHF-UCL
- cell surface Source: BHF-UCL
- dendrite Source: BHF-UCL
- intercalated disc Source: MGI
- membrane Source: MGI
- neuromuscular junction Source: BHF-UCL
- neuron projection Source: MGI
- node of Ranvier Source: BHF-UCL
- paranode region of axon Source: MGI
- synapse Source: MGI
- Z disc Source: BHF-UCL
Keywords - Cellular componenti
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Lysosome, Membrane, Postsynaptic cell membrane, SynapsePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000419782 | 1 – 1961 | Ankyrin-3Add BLAST | 1961 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Modified residuei | 22 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 606 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 830 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 844 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 850 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 873 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 914 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 917 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 923 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 958 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 960 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 1114 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1451 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1462 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1470 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1473 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1795 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1813 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 1883 | PhosphoserineBy similarity | 1 | ||
Isoform 6 (identifier: G5E8K5-6) | |||||
Modified residuei | 732 | PhosphoserineCombined sources | 1 | ||
Isoform 2 (identifier: G5E8K5-2) | |||||
Modified residuei | 830 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 1560 | PhosphoserineCombined sources | 1 | ||
Isoform 3 (identifier: G5E8K5-3) | |||||
Modified residuei | 830 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | G5E8K5 |
MaxQBi | G5E8K5 |
PaxDbi | G5E8K5 |
PRIDEi | G5E8K5 |
PTM databases
iPTMneti | G5E8K5 |
PhosphoSitePlusi | G5E8K5 |
SwissPalmi | G5E8K5 |
Expressioni
Tissue specificityi
Developmental stagei
Inductioni
Gene expression databases
Bgeei | ENSMUSG00000069601, Expressed in ventral horn of spinal cord and 301 other tissues |
Genevisiblei | G5E8K5, MM |
Interactioni
Subunit structurei
May be a constituent of a NFASC/NRCAM/ankyrin G complex.
Interacts with RHBG (By similarity). Directly interacts with DMD and betaDAG1; this interaction does not interfere with DMD-binding and is required for DMD and betaDAG1 retention at costameres.
Interacts (via N-terminal ANK repeats) with SCHIP1 isoform 7 (via C-terminus); this interaction is required for the localization at axon initial segments (AISs) and nodes of Ranvier (NRs).
Interacts with PLEC and FLNC (By similarity).
Interacts with KCNA1; this inhibits channel activity (PubMed:23903368).
Interacts with SCN5A (By similarity).
By similarity2 PublicationsGO - Molecular functioni
- cadherin binding Source: BHF-UCL
- cytoskeletal protein binding Source: BHF-UCL
- ion channel binding Source: UniProtKB
- phosphorylation-dependent protein binding Source: MGI
- spectrin binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 198102, 7 interactors |
IntActi | G5E8K5, 10 interactors |
MINTi | G5E8K5 |
STRINGi | 10090.ENSMUSP00000090089 |
Miscellaneous databases
RNActi | G5E8K5, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 56 – 85 | ANK 1Add BLAST | 30 | |
Repeati | 89 – 118 | ANK 2Add BLAST | 30 | |
Repeati | 122 – 151 | ANK 3Add BLAST | 30 | |
Repeati | 155 – 184 | ANK 4Add BLAST | 30 | |
Repeati | 186 – 213 | ANK 5Add BLAST | 28 | |
Repeati | 217 – 246 | ANK 6Add BLAST | 30 | |
Repeati | 250 – 279 | ANK 7Add BLAST | 30 | |
Repeati | 283 – 312 | ANK 8Add BLAST | 30 | |
Repeati | 316 – 345 | ANK 9Add BLAST | 30 | |
Repeati | 349 – 378 | ANK 10Add BLAST | 30 | |
Repeati | 382 – 411 | ANK 11Add BLAST | 30 | |
Repeati | 415 – 444 | ANK 12Add BLAST | 30 | |
Repeati | 448 – 477 | ANK 13Add BLAST | 30 | |
Repeati | 481 – 510 | ANK 14Add BLAST | 30 | |
Repeati | 514 – 543 | ANK 15Add BLAST | 30 | |
Repeati | 547 – 576 | ANK 16Add BLAST | 30 | |
Repeati | 580 – 609 | ANK 17Add BLAST | 30 | |
Repeati | 613 – 642 | ANK 18Add BLAST | 30 | |
Repeati | 646 – 675 | ANK 19Add BLAST | 30 | |
Repeati | 679 – 708 | ANK 20Add BLAST | 30 | |
Repeati | 712 – 741 | ANK 21Add BLAST | 30 | |
Repeati | 745 – 774 | ANK 22Add BLAST | 30 | |
Repeati | 778 – 807 | ANK 23Add BLAST | 30 | |
Domaini | 985 – 1140 | ZU5 1PROSITE-ProRule annotationAdd BLAST | 156 | |
Domaini | 1142 – 1289 | ZU5 2PROSITE-ProRule annotationAdd BLAST | 148 | |
Domaini | 1478 – 1562 | DeathPROSITE-ProRule annotationAdd BLAST | 85 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1274 – 1408 | UPA domainBy similarityAdd BLAST | 135 |
Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
eggNOGi | KOG4177, Eukaryota |
GeneTreei | ENSGT00940000154939 |
HOGENOMi | CLU_000134_7_2_1 |
InParanoidi | G5E8K5 |
OrthoDBi | 1011028at2759 |
TreeFami | TF351263 |
Family and domain databases
CDDi | cd08803, Death_ank3, 1 hit |
Gene3Di | 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR037971, Ank3_Death IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 7 hits PF13606, Ank_3, 1 hit PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 22 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 21 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
s (6+)i Sequence
Sequence statusi: Complete.
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 24 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSEEPKEKPA KPAHRKRKGK KSDANASYLR AARAGHLEKA LDYIKNGVDV
60 70 80 90 100
NICNQNGLNA LHLASKEGHV EVVSELLQRE ANVDAATKKG NTALHIASLA
110 120 130 140 150
GQAEVVKVLV TNGANVNAQS QNGFTPLYMA AQENHLEVVR FLLDNGASQS
160 170 180 190 200
LATEDGFTPL AVALQQGHDQ VVSLLLENDT KGKVRLPALH IAARKDDTKA
210 220 230 240 250
AALLLQNDTN ADVESKSGFT PLHIAAHYGN INVATLLLNR AAAVDFTARN
260 270 280 290 300
DITPLHVASK RGNANMVKLL LDRGAKIDAK TRDGLTPLHC GARSGHEQVV
310 320 330 340 350
EMLLDRSAPI LSKTKNGLSP LHMATQGDHL NCVQLLLQHN VPVDDVTNDY
360 370 380 390 400
LTALHVAAHC GHYKVAKVLL DKKASPNAKA LNGFTPLHIA CKKNRIRVME
410 420 430 440 450
LLLKHGASIQ AVTESGLTPI HVAAFMGHVN IVSQLMHHGA SPNTTNVRGE
460 470 480 490 500
TALHMAARSG QAEVVRYLVQ DGAQVEAKAK DDQTPLHISA RLGKADIVQQ
510 520 530 540 550
LLQQGASPNA ATTSGYTPLH LAAREGHEDV AAFLLDHGAS LSITTKKGFT
560 570 580 590 600
PLHVAAKYGK LEVASLLLQK SASPDAAGKS GLTPLHVAAH YDNQKVALLL
610 620 630 640 650
LDQGASPHAA AKNGYTPLHI AAKKNQMDIA TSLLEYGADA NAVTRQGIAS
660 670 680 690 700
VHLAAQEGHV DMVSLLLSRN ANVNLSNKSG LTPLHLAAQE DRVNVAEVLV
710 720 730 740 750
NQGAHVDAQT KMGYTPLHVG CHYGNIKIVN FLLQHSAKVN AKTKNGYTAL
760 770 780 790 800
HQAAQQGHTH IINVLLQNNA SPNELTVNGN TALAIARRLG YISVVDTLKV
810 820 830 840 850
VTEEIMTTTT ITEKHKMNVP ETMNEVLDMS DDEVRKASAP EKLSDGEYIS
860 870 880 890 900
DGEEGDKCTW FKIPKVQEVL VKSEDAITGD TDKYLGPQDL KELGDDSLPA
910 920 930 940 950
EGYVGFSLGA RSASLRSFSS DRSYTLNRSS YARDSMMIEE LLVPSKEQHL
960 970 980 990 1000
TFTREFDSDS LRHYSWAADT LDNVNLVSSP VHSGFLVSFM VDARGGSMRG
1010 1020 1030 1040 1050
SRHHGMRIII PPRKCTAPTR ITCRLVKRHK LANPPPMVEG EGLASRLVEM
1060 1070 1080 1090 1100
GPAGAQFLGP VIVEIPHFGS MRGKERELIV LRSENGETWK EHQFDSKNED
1110 1120 1130 1140 1150
LAELLNGMDE ELDSPEELGT KRICRIITKD FPQYFAVVSR IKQESNQIGP
1160 1170 1180 1190 1200
EGGILSSTTV PLVQASFPEG ALTKRIRVGL QAQPVPEETV KKILGNKATF
1210 1220 1230 1240 1250
SPIVTVEPRR RKFHKPITMT IPVPPPSGEG VSNGYKGDAT PNLRLLCSIT
1260 1270 1280 1290 1300
GGTSPAQWED ITGTTPLTFI KDCVSFTTNV SARFWLADCH QVLETVGLAS
1310 1320 1330 1340 1350
QLYRELICVP YMAKFVVFAK TNDPVESSLR CFCMTDDRVD KTLEQQENFE
1360 1370 1380 1390 1400
EVARSKDIEV LEGKPIYVDC YGNLAPLTKG GQQLVFNFYS FKENRLPFSI
1410 1420 1430 1440 1450
KIRDTSQEPC GRLSFLKEPK TTKGLPQTAV CNLNITLPAH KKAEKADRRQ
1460 1470 1480 1490 1500
SFASLALRKR YSYLTEPSMS PQSPCERTDI RMAIVADHLG LSWTELAREL
1510 1520 1530 1540 1550
NFSVDEINQI RVENPNSLIS QSFMLLKKWV TRDGKNATTD ALTSVLTKIN
1560 1570 1580 1590 1600
RIDIVTLLEG PIFDYGNISG TRSFADENNV FHDPVDGHPS FQVELETPMG
1610 1620 1630 1640 1650
LYCTPPNPFQ QDDHFSDISS IESPFRTPSR LSDGLVPSQG NIEHPTGGPP
1660 1670 1680 1690 1700
VVTAEDTSLE DSKMDDSVTV TDPADPLDVD ESQLKDLCQS ECAQCWASVP
1710 1720 1730 1740 1750
GIPNDGRQAE PLRPQTRKVG MSSEQQEKGK SGPDEEVTED KVKSLFEDIQ
1760 1770 1780 1790 1800
LEEVEAEEMT EDQGQAMLNR VQRAELAMSS LAGWQNETPS GSLESPAQAR
1810 1820 1830 1840 1850
RLTGGLLDRL DDSSDQARDS ITSYLTGEPG KIEANGNHTA EVIPEAKAKP
1860 1870 1880 1890 1900
YFPESQNDIG KQSIKENLKP KTHGCGRTEE PVSPLTAYQK SLEETSKLVI
1910 1920 1930 1940 1950
EDAPKPCVPV GMKKMTRTTA DGKARLNLQE EEGSTRSEPK QGEGYKVKTK
1960
KEIRNVEKKT H
Computationally mapped potential isoform sequencesi
There are 24 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketS4R2S8 | S4R2S8_MOUSE | Ankyrin-3 | Ank3 | 1,985 | Annotation score: | ||
S4R236 | S4R236_MOUSE | Ankyrin-3 | Ank3 | 1,181 | Annotation score: | ||
S4R2K9 | S4R2K9_MOUSE | Ankyrin-3 | Ank3 | 2,622 | Annotation score: | ||
S4R1S2 | S4R1S2_MOUSE | Ankyrin-3 | Ank3 | 1,807 | Annotation score: | ||
A0A1W2P812 | A0A1W2P812_MOUSE | Ankyrin-3 | Ank3 | 1,758 | Annotation score: | ||
S4R165 | S4R165_MOUSE | Ankyrin-3 | Ank3 | 1,174 | Annotation score: | ||
S4R2J6 | S4R2J6_MOUSE | Ankyrin-3 | Ank3 | 1,157 | Annotation score: | ||
G5E8K2 | G5E8K2_MOUSE | Ankyrin-3 | Ank3 | 1,940 | Annotation score: | ||
G5E8K3 | G5E8K3_MOUSE | Ankyrin-3 | Ank3 | 1,943 | Annotation score: | ||
G3X971 | G3X971_MOUSE | Ankyrin-3 | Ank3 | 838 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 717 | L → P in AAH21657 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 1603 | C → W in AAB01607 (PubMed:7615634).Curated | 1 | |
Sequence conflicti | 1603 | C → W in AAB01603 (PubMed:7615634).Curated | 1 | |
Sequence conflicti | 1603 | C → W in AAB58381 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 1652 | V → I in BAC29151 (PubMed:16141072).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_044355 | 1 – 867 | Missing in isoform 4, isoform 5 and isoform 6. 2 PublicationsAdd BLAST | 867 | |
Alternative sequenceiVSP_044356 | 834 – 873 | VRKAS…VLVKS → G in isoform 2 and isoform 3. 2 PublicationsAdd BLAST | 40 | |
Alternative sequenceiVSP_044357 | 868 – 872 | EVLVK → MALPH in isoform 4, isoform 5 and isoform 6. 2 Publications | 5 | |
Alternative sequenceiVSP_044358 | 1588 – 1783 | Missing in isoform 2 and isoform 6. 3 PublicationsAdd BLAST | 196 | |
Alternative sequenceiVSP_044359 | 1941 | Missing in isoform 5. 1 Publication | 1 |
Sequence databases
Genome annotation databases
Ensembli | ENSMUST00000054167; ENSMUSP00000061698; ENSMUSG00000069601 [G5E8K5-3] ENSMUST00000092433; ENSMUSP00000090089; ENSMUSG00000069601 [G5E8K5-4] ENSMUST00000092434; ENSMUSP00000090090; ENSMUSG00000069601 [G5E8K5-1] ENSMUST00000181974; ENSMUSP00000138285; ENSMUSG00000069601 [G5E8K5-6] ENSMUST00000182029; ENSMUSP00000138337; ENSMUSG00000069601 [G5E8K5-5] ENSMUST00000182155; ENSMUSP00000138347; ENSMUSG00000069601 [G5E8K5-2] ENSMUST00000182884; ENSMUSP00000138326; ENSMUSG00000069601 [G5E8K5-1] |
GeneIDi | 11735 |
KEGGi | mmu:11735 |
UCSCi | uc007fmw.1, mouse [G5E8K5-1] uc007fna.1, mouse [G5E8K5-2] uc007fnb.1, mouse [G5E8K5-3] uc007fnh.1, mouse [G5E8K5-6] uc007fni.1, mouse [G5E8K5-5] uc007fnk.1, mouse [G5E8K5-4] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
3D structure databases
SMRi | G5E8K5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 198102, 7 interactors |
IntActi | G5E8K5, 10 interactors |
MINTi | G5E8K5 |
STRINGi | 10090.ENSMUSP00000090089 |
PTM databases
iPTMneti | G5E8K5 |
PhosphoSitePlusi | G5E8K5 |
SwissPalmi | G5E8K5 |
Proteomic databases
jPOSTi | G5E8K5 |
MaxQBi | G5E8K5 |
PaxDbi | G5E8K5 |
PRIDEi | G5E8K5 |
Protocols and materials databases
ABCDi | G5E8K5, 6 sequenced antibodies |
Antibodypediai | 4197, 265 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000054167; ENSMUSP00000061698; ENSMUSG00000069601 [G5E8K5-3] ENSMUST00000092433; ENSMUSP00000090089; ENSMUSG00000069601 [G5E8K5-4] ENSMUST00000092434; ENSMUSP00000090090; ENSMUSG00000069601 [G5E8K5-1] ENSMUST00000181974; ENSMUSP00000138285; ENSMUSG00000069601 [G5E8K5-6] ENSMUST00000182029; ENSMUSP00000138337; ENSMUSG00000069601 [G5E8K5-5] ENSMUST00000182155; ENSMUSP00000138347; ENSMUSG00000069601 [G5E8K5-2] ENSMUST00000182884; ENSMUSP00000138326; ENSMUSG00000069601 [G5E8K5-1] |
GeneIDi | 11735 |
KEGGi | mmu:11735 |
UCSCi | uc007fmw.1, mouse [G5E8K5-1] uc007fna.1, mouse [G5E8K5-2] uc007fnb.1, mouse [G5E8K5-3] uc007fnh.1, mouse [G5E8K5-6] uc007fni.1, mouse [G5E8K5-5] uc007fnk.1, mouse [G5E8K5-4] |
Organism-specific databases
CTDi | 288 |
MGIi | MGI:88026, Ank3 |
Phylogenomic databases
eggNOGi | KOG4177, Eukaryota |
GeneTreei | ENSGT00940000154939 |
HOGENOMi | CLU_000134_7_2_1 |
InParanoidi | G5E8K5 |
OrthoDBi | 1011028at2759 |
TreeFami | TF351263 |
Miscellaneous databases
BioGRID-ORCSi | 11735, 0 hits in 17 CRISPR screens |
ChiTaRSi | Ank3, mouse |
PROi | PR:G5E8K5 |
RNActi | G5E8K5, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000069601, Expressed in ventral horn of spinal cord and 301 other tissues |
Genevisiblei | G5E8K5, MM |
Family and domain databases
CDDi | cd08803, Death_ank3, 1 hit |
Gene3Di | 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR037971, Ank3_Death IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 7 hits PF13606, Ank_3, 1 hit PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 22 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 21 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ANK3_MOUSE | |
Accessioni | G5E8K5Primary (citable) accession number: G5E8K5 Secondary accession number(s): G5E8K4 Q8VC68 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2012 |
Last sequence update: | December 14, 2011 | |
Last modified: | February 10, 2021 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot