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Protein
Submitted name:

G protein-coupled receptor, family C, group 5, member A

Gene

Gprc5a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor, family C, group 5, member AImported
Submitted name:
Retinoic acid-induced protein 3Imported
Gene namesi
Name:Gprc5aImported
ORF Names:mCG_22262Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1891250 Gprc5a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei67 – 89HelicalSequence analysisAdd BLAST23
Transmembranei101 – 122HelicalSequence analysisAdd BLAST22
Transmembranei134 – 159HelicalSequence analysisAdd BLAST26
Transmembranei179 – 201HelicalSequence analysisAdd BLAST23
Transmembranei213 – 234HelicalSequence analysisAdd BLAST22
Transmembranei246 – 264HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000046733 Expressed in 104 organ(s), highest expression level in lung

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 268G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST222

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIGU Eukaryota
ENOG410YD51 LUCA
GeneTreeiENSGT00520000055551
KOiK08468
OMAiWDDTILS
OrthoDBiEOG091G0DAG
TreeFamiTF321410

Family and domain databases

InterProiView protein in InterPro
IPR017978 GPCR_3_C
PfamiView protein in Pfam
PF00003 7tm_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G5E8C3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTPRAAPSG CRSDLDSRYH RLCDLAEGWG IALETLAAVG AVATVACMFA
60 70 80 90 100
LVFLICKVQD SNKRKMLPAQ FLFLLGVLGV FGLTFAFIIK LDGATGPTRF
110 120 130 140 150
FLFGVLFAIC FSCLLAHAFN LIKLVRGRKP LSWLVILSLA VGFSLVQDVI
160 170 180 190 200
AIEYLVLTMN RTNVNVFSEL PAPRRNEDFV MLLIYVLVLM VLTFFASFLV
210 220 230 240 250
FCGSFSGWKR HGFHICFTSF LSIAIWVAWI VLLLIPDIDR KWDDTILSTA
260 270 280 290 300
LVANGWVFLA FYILPEFRQL PRQRSPTDYP VEDAFCKPQL MKQSYGVENR
310 320 330 340 350
AYSQEEITQG LEMGDTLYAP YSTHFQLQNH QKDFSIPRAQ APASPYNDYE

GRKGDS
Length:356
Mass (Da):40,096
Last modified:December 14, 2011 - v1
Checksum:i3BA6E854F8B59B6E
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8BHL4RAI3_MOUSE
Retinoic acid-induced protein 3
Gprc5a Rai3, Raig1
356Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140287 Genomic DNA No translation available.
CH466572 Genomic DNA Translation: EDL10540.1
RefSeqiNP_852109.2, NM_181444.5
XP_006506101.1, XM_006506038.2
UniGeneiMm.23575
Mm.477015

Genome annotation databases

EnsembliENSMUST00000050104; ENSMUSP00000061062; ENSMUSG00000046733
GeneIDi232431
KEGGimmu:232431
UCSCiuc009ele.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140287 Genomic DNA No translation available.
CH466572 Genomic DNA Translation: EDL10540.1
RefSeqiNP_852109.2, NM_181444.5
XP_006506101.1, XM_006506038.2
UniGeneiMm.23575
Mm.477015

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000050104; ENSMUSP00000061062; ENSMUSG00000046733
GeneIDi232431
KEGGimmu:232431
UCSCiuc009ele.2 mouse

Organism-specific databases

CTDi9052
MGIiMGI:1891250 Gprc5a

Phylogenomic databases

eggNOGiENOG410IIGU Eukaryota
ENOG410YD51 LUCA
GeneTreeiENSGT00520000055551
KOiK08468
OMAiWDDTILS
OrthoDBiEOG091G0DAG
TreeFamiTF321410

Miscellaneous databases

ChiTaRSiGprc5a mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046733 Expressed in 104 organ(s), highest expression level in lung

Family and domain databases

InterProiView protein in InterPro
IPR017978 GPCR_3_C
PfamiView protein in Pfam
PF00003 7tm_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG5E8C3_MOUSE
AccessioniPrimary (citable) accession number: G5E8C3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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