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Protein

Oxysterol-binding protein

Gene

Osbpl11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processLipid transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Oxysterol-binding proteinUniRule annotation
Gene namesi
Name:Osbpl11Imported
ORF Names:mCG_130137Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2146553 Osbpl11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000022807 Expressed in 285 organ(s), highest expression level in primary oocyte

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 166PHInterPro annotationAdd BLAST98

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili701 – 721Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the OSBP family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2210 Eukaryota
ENOG410XRW6 LUCA
GeneTreeiENSGT00550000074515
KOiK20465
OMAiFHCSWRM
OrthoDBiEOG091G0FV2
TreeFamiTF312807

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR10972 PTHR10972, 1 hit
PfamiView protein in Pfam
PF01237 Oxysterol_BP, 1 hit
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF144000 SSF144000, 1 hit
PROSITEiView protein in PROSITE
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G5E8A0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNFGVKMQGG EPASVMKVSE SEGKLEGLAT AVTPNKNSGN SSCGGAISSS
60 70 80 90 100
SSNSSRGGSA KGWQYSDHME SVNGYLMKYT NLVTGWQYRF FVLNNEAGLL
110 120 130 140 150
EYFVNEQSRN QKPRGTLQLA GAVISPSDED SHTFTVNAAS GEQYKLRATD
160 170 180 190 200
AKERQHWVSR LQICTQHHTE AIGKNNPPLK SRSFSLASSG NSPISQRRPS
210 220 230 240 250
QNAMSFFNVG HSKLQSVNKR AHLHPDHLVE VREMMSHAEG QQRDLIRRIE
260 270 280 290 300
CLPASGLLSS LDQDLLMLKA TSMATMNCLN DCFHILQLQH ASHQKGALPS
310 320 330 340 350
GTTIEWLEPK IPLSNHYKNG AEQPFATEPN KPMGAPEAQC VAESGVLARE
360 370 380 390 400
PEDINADDEV EDTCDNKEDD LGAVEEQRSV ILHLLSQLKL GMDLTRVVLP
410 420 430 440 450
TFILEKRSLL EMYADFMSHP DLFIGITNGA TPEDRMIRFV EYYLTSFHEG
460 470 480 490 500
RKGAIAKKPY NPIIGETFHC SWRMPKSEVA SGVSSSSSTP AITDHAPLPE
510 520 530 540 550
EAPTQSVSDC YTVRFVAEQV SHHPPVSGFY AECAERKMCV NAHVWTKSKF
560 570 580 590 600
LGMSIGVTMV GEGVLCLLEH GEEYTFSLPC AYARSILTVP WVELGGKVSV
610 620 630 640 650
NCAKTGYSAS ITFHTKPFYG GKLHRVTAEV KYNLTNTVVC RVQGEWNSVL
660 670 680 690 700
EFTYSNGETK FVDLAKLAVT KKRVRPLEKQ DPFESRRLWK NVTDSLRESE
710 720 730 740 750
IDKATEHKRS LEERQRTEER LRTETGTPWK TKYFIKEGDG WVYHKPLWKG

IPSQPAE
Length:757
Mass (Da):84,333
Last modified:December 14, 2011 - v1
Checksum:iD0B0E59067F72128
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8CI95OSB11_MOUSE
Oxysterol-binding protein-related p...
Osbpl11
751Annotation score:
A0A338P6F2A0A338P6F2_MOUSE
Oxysterol-binding protein
Osbpl11
751Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124195 Genomic DNA No translation available.
AC145198 Genomic DNA No translation available.
CH466521 Genomic DNA Translation: EDK97836.1
RefSeqiNP_789810.2, NM_176840.3
UniGeneiMm.486405

Genome annotation databases

EnsembliENSMUST00000039733; ENSMUSP00000039632; ENSMUSG00000022807
ENSMUST00000232181; ENSMUSP00000155873; ENSMUSG00000022807
GeneIDi106326
KEGGimmu:106326
UCSCiuc007yzy.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124195 Genomic DNA No translation available.
AC145198 Genomic DNA No translation available.
CH466521 Genomic DNA Translation: EDK97836.1
RefSeqiNP_789810.2, NM_176840.3
UniGeneiMm.486405

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039733; ENSMUSP00000039632; ENSMUSG00000022807
ENSMUST00000232181; ENSMUSP00000155873; ENSMUSG00000022807
GeneIDi106326
KEGGimmu:106326
UCSCiuc007yzy.2 mouse

Organism-specific databases

CTDi114885
MGIiMGI:2146553 Osbpl11

Phylogenomic databases

eggNOGiKOG2210 Eukaryota
ENOG410XRW6 LUCA
GeneTreeiENSGT00550000074515
KOiK20465
OMAiFHCSWRM
OrthoDBiEOG091G0FV2
TreeFamiTF312807

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022807 Expressed in 285 organ(s), highest expression level in primary oocyte

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR10972 PTHR10972, 1 hit
PfamiView protein in Pfam
PF01237 Oxysterol_BP, 1 hit
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF144000 SSF144000, 1 hit
PROSITEiView protein in PROSITE
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG5E8A0_MOUSE
AccessioniPrimary (citable) accession number: G5E8A0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 7, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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