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Protein
Submitted name:

Helicase swr-1

Gene

NEUTE2DRAFT_95178

Organism
Neurospora tetrasperma (strain FGSC 2509 / P0656)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Helicase swr-1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:NEUTE2DRAFT_95178Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeurospora tetrasperma (strain FGSC 2509 / P0656)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri510952 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008513 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini418 – 493HSAInterPro annotationAdd BLAST76
Domaini957 – 1122Helicase ATP-bindingInterPro annotationAdd BLAST166
Domaini1510 – 1660Helicase C-terminalInterPro annotationAdd BLAST151

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili519 – 547Sequence analysisAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

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OMAi
RQGWNND

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00079 HELICc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR014012 HSA_dom
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51204 HSA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G4UXX7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTMMTDSGT ASDSGAGLVD STRNDTTTTT TTTSATTTTP GDNDADDNNT
60 70 80 90 100
NGTTGHHDNN ETDNKSYSST HHVPAIDNTS TTTNANANAE DAGFLDRDQS
110 120 130 140 150
PLSSISSPLS EPDNFEFDTE PISSILSPKS TTSDTHARDG ETPELDEDGQ
160 170 180 190 200
PPAKRRRVRE TTPHNHSRKP KPESPPWKKF EAEGPTTIIT EDGRRKSGRV
210 220 230 240 250
NPVLLGMKPS DKKVTRKAIQ TSPVSNKSSA STSRKPAPAS SSSKPAPAKM
260 270 280 290 300
PPPPPPKAPA RKSATTHDTR PSASRSRRRS PSPRRPATPP KPAAVGTRRS
310 320 330 340 350
TRQALAHSRA SYDDGQLSPG ASRATPRIKL KVRPPLTVIP LVHPNQANVR
360 370 380 390 400
PKLGPTFEEY FARAQEIPVE EGGQHIPDEE PKYTDEMALQ DAKVILRVEK
410 420 430 440 450
EVEPGGLLAP DRCSAFEPEA EEEPPRQWAH LDHLTKAMTN FRKLMYREQQ
460 470 480 490 500
LHMQAAKRIA IACEAEWRRR NPQPKTAEEI ELEEMEASKA KWRQVIRAFA
510 520 530 540 550
GTWENVRVEV NRRRLVEWEA EEQRRVKAAL NQAVNLSEQK LQQRQAQVDG
560 570 580 590 600
DEITDEDEDE DDEDLESGMP SVMGDEEESD EHSDQGSNEM SDENDEDEDE
610 620 630 640 650
DNMSSSSEDD DKKSTASDEG LTQEELRAKY ANLPTLDTTD GNKETTKDVE
660 670 680 690 700
MADASAAMDG SVANGDDTSD ESVDMDDDLG SSEESDDDEE DEDDEEEEES
710 720 730 740 750
DDEPAGLLGL FFGKSELKKL KEEAVTEEPS VESAGDVEMT DAPAALRPEP
760 770 780 790 800
QVDGHAHEAP ITNGSHTNEQ LASSQTEGAD DEVSLLIIPN DEKAAENTQT
810 820 830 840 850
TKEPGSGVAN KDFLTNGSSL KHHEEIVQSE NQALPAKESV EAGGDLPMVD
860 870 880 890 900
APPTDDLQRE TAAAPSLEAP PNTRHDSQET VAATDMQSQS QTQSPKTTDT
910 920 930 940 950
KPTDVDTPHS ELAVSVQKPD SRQSSPQPTT PTVKTEIPFL LRGTLREYQH
960 970 980 990 1000
HGLDWLAGLY ANNTNGILAD EMGLGKTIQT IALLAHLACH HEVWGPHLVI
1010 1020 1030 1040 1050
VPTSVMLNWE MEFKKWCPGF KILTYYGNQE ERKRKRQGWN NDDVWNVCIT
1060 1070 1080 1090 1100
SYQMVLQDQQ VFRRRRWHYM ILDEAHNIKN FKSQRWQTLL GFNTQARLLL
1110 1120 1130 1140 1150
TGTPLQNNLT ELWSLLYFLA PPENGEGGFV DLTEFHNWFA RPESQILESG
1160 1170 1180 1190 1200
REQLDDEARA IIAKLHKVLR PYLLRRLKAD VEKQMPAKYE HVEFCRLSKR
1210 1220 1230 1240 1250
QRELYDGFLS RADTRETLQS GNYMSIINCL MQLRKVCNHP DLFVDRPIMT
1260 1270 1280 1290 1300
SFRMSRSVPA DYEWNEKFIR NRLLVTKPMT TVNLSFLNMI PTEYEDLSKT
1310 1320 1330 1340 1350
HTDRIAQLSS HRILLDLREA QKVRANNAYT ALDPSSVKSN LVYLESAARW
1360 1370 1380 1390 1400
GRFEELQHCV YINALRRQQR PIYGKRLTEF LTLDTHLRPY KPRPRVPAKI
1410 1420 1430 1440 1450
MSWFEEDSFL LHNAIPTLQQ RAESMEMTIT KFACVTPAVV TGPEMNRFLL
1460 1470 1480 1490 1500
GERGIQLFEE LDLKLSAPVK YAPYMPPQPP PDPWHEARMR LTIQFPDKRL
1510 1520 1530 1540 1550
LQYDCGKLQA LDKLLRKLQA GGHRALIFTQ MTKVLDILEQ FLNIHGHKYL
1560 1570 1580 1590 1600
RLDGATKVEQ RQILTDRFNH DPRILCFILS TRSGGLGINL TGADTVIFYD
1610 1620 1630 1640 1650
QDWNPAMDKQ CQDRCHRIGQ TRDVHIYRLV SEHTIEANIL RKASQKQMLD
1660 1670 1680 1690 1700
DVVIQEGEFT TDYFNRLSVR DVLGSNGEVI ASNEDDVAAN LAMDRVLGGP
1710 1720 1730 1740 1750
STTGAGGDDG TADGGGASQP LPVRNVGRVL EMAEDREDVD AAKAAEKEIM
1760 1770 1780 1790 1800
QDEADFGEAG STRPGTPGDG LADLDGQLLG GEENKEVEEE VIEYNAWGER
1810 1820 1830 1840
MHTIDEYMLG FMAKALEGTP LELPRDRKKG RDRNRNRKGK DTRKR
Length:1,845
Mass (Da):206,761
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF821D3579E61DE00
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GL891258 Genomic DNA Translation: EGZ69775.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
EGZ69775; EGZ69775; NEUTE2DRAFT_95178

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL891258 Genomic DNA Translation: EGZ69775.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEGZ69775; EGZ69775; NEUTE2DRAFT_95178

Phylogenomic databases

OMAiRQGWNND

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR014012 HSA_dom
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51204 HSA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG4UXX7_NEUT9
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G4UXX7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: January 16, 2019
This is version 24 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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