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Protein
Submitted name:

Lysophosphatidic acid receptor 5

Gene

Lpar5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-MMU-416476 G alpha (q) signalling events
R-MMU-418594 G alpha (i) signalling events
R-MMU-419408 Lysosphingolipid and LPA receptors

Names & Taxonomyi

Protein namesi
Submitted name:
Lysophosphatidic acid receptor 5Imported
Submitted name:
MCG142734, isoform CRA_aImported
Gene namesi
Name:Lpar5Imported
ORF Names:mCG_142734Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:2685918 Lpar5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 64HelicalSequence analysisAdd BLAST23
Transmembranei76 – 95HelicalSequence analysisAdd BLAST20
Transmembranei115 – 133HelicalSequence analysisAdd BLAST19
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Transmembranei204 – 228HelicalSequence analysisAdd BLAST25
Transmembranei249 – 273HelicalSequence analysisAdd BLAST25
Transmembranei293 – 315HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000067714 Expressed in 27 organ(s), highest expression level in embryo

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 313G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST259

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IF9D Eukaryota
ENOG410XTCM LUCA
GeneTreeiENSGT00920000148939
KOiK08390
OMAiRCRYRDL
OrthoDBiEOG091G091Z
TreeFamiTF350009

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G3X9K0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQTNFSSHL DMMFANSSAN TTSTNSSVLQ CPDYRDTHRL HMVVYSLVLA
60 70 80 90 100
TGLPLNALAL WVFLRVLRVH SVVSVYMCNL AASDLLFTLS LPLRLSYYAQ
110 120 130 140 150
HHWPFPGFLC QTSGAIFQMN MYGSCLFLML INVDRYAAIV HPLRLRHLRR
160 170 180 190 200
PRVARRLCLG VWALILLFAV PAARVHSPSH CTYKNITVRL CFESFSDELW
210 220 230 240 250
KGRLLPLLLL AEILGFLLPL AAVVYSSGRV FWTLARPDAT QSQRRRKTVR
260 270 280 290 300
LLLANLIIFL LCFVPYNSTL AVYGLLRANL VKNSIQDRDQ VRGVLMIMVL
310 320 330 340 350
LAGANCVLDP LVYYFSAEGF RNTLRNLGAP LNTRPLATNG AAGVLTELPS
360 370 380
ESTQNTGQDA TSQVLLQPAT LGTPPDNCSQ DSAL
Length:384
Mass (Da):42,783
Last modified:November 16, 2011 - v1
Checksum:i756983D6C220E580
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q149R9LPAR5_MOUSE
Lysophosphatidic acid receptor 5
Lpar5 Gm1072, Gpr92
372Annotation score:
F6S365F6S365_MOUSE
Lysophosphatidic acid receptor 5
Lpar5
163Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134529 Genomic DNA No translation available.
CH466523 Genomic DNA Translation: EDK99799.1
CH466523 Genomic DNA Translation: EDK99800.1
RefSeqiNP_001156740.1, NM_001163268.1
NP_001156741.1, NM_001163269.1
XP_006506403.1, XM_006506340.3
UniGeneiMm.333386

Genome annotation databases

EnsembliENSMUST00000088292; ENSMUSP00000085630; ENSMUSG00000067714
ENSMUST00000171989; ENSMUSP00000132511; ENSMUSG00000067714
GeneIDi381810
KEGGimmu:381810
UCSCiuc009dtj.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134529 Genomic DNA No translation available.
CH466523 Genomic DNA Translation: EDK99799.1
CH466523 Genomic DNA Translation: EDK99800.1
RefSeqiNP_001156740.1, NM_001163268.1
NP_001156741.1, NM_001163269.1
XP_006506403.1, XM_006506340.3
UniGeneiMm.333386

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000088292; ENSMUSP00000085630; ENSMUSG00000067714
ENSMUST00000171989; ENSMUSP00000132511; ENSMUSG00000067714
GeneIDi381810
KEGGimmu:381810
UCSCiuc009dtj.1 mouse

Organism-specific databases

CTDi57121
MGIiMGI:2685918 Lpar5

Phylogenomic databases

eggNOGiENOG410IF9D Eukaryota
ENOG410XTCM LUCA
GeneTreeiENSGT00920000148939
KOiK08390
OMAiRCRYRDL
OrthoDBiEOG091G091Z
TreeFamiTF350009

Enzyme and pathway databases

ReactomeiR-MMU-416476 G alpha (q) signalling events
R-MMU-418594 G alpha (i) signalling events
R-MMU-419408 Lysosphingolipid and LPA receptors

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000067714 Expressed in 27 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3X9K0_MOUSE
AccessioniPrimary (citable) accession number: G3X9K0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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