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Protein
Submitted name:

SEC24 related gene family, member C (S. cerevisiae), isoform CRA_a

Gene

Sec24c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportSAAS annotation, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005 COPII-mediated vesicle transport
R-MMU-2132295 MHC class II antigen presentation
R-MMU-5694530 Cargo concentration in the ER
R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Names & Taxonomyi

Protein namesi
Submitted name:
SEC24 related gene family, member C (S. cerevisiae), isoform CRA_aImported
Submitted name:
Sec24-related gene family, member C (S. cerevisiae)Imported
Gene namesi
Name:Sec24cImported
ORF Names:mCG_121333Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1919746 Sec24c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000039367 Expressed in 290 organ(s), highest expression level in small intestine

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiG3X972, 61 interactors
G3X972, 61 interactors
STRINGi10090.ENSMUSP00000045955

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini424 – 462zf-Sec23_Sec24InterPro annotationAdd BLAST39
Domaini501 – 745Sec23_trunkInterPro annotationAdd BLAST245
Domaini750 – 833Sec23_BSInterPro annotationAdd BLAST84
Domaini846 – 945Sec23_helicalInterPro annotationAdd BLAST100
Domaini965 – 1036Gelsolin-likeInterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1985 Eukaryota
COG5028 LUCA
GeneTreeiENSGT00590000082962
OrthoDBiEOG091G0288
TreeFamiTF300464

Family and domain databases

Gene3Di3.40.20.10, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR036180 Gelsolin-like_dom_sf
IPR006900 Sec23/24_helical_dom
IPR036175 Sec23/24_helical_dom_sf
IPR006896 Sec23/24_trunk_dom
IPR012990 Sec23_24_beta_S
IPR036465 vWFA_dom_sf
IPR006895 Znf_Sec23_Sec24
IPR036174 Znf_Sec23_Sec24_sf
PfamiView protein in Pfam
PF00626 Gelsolin, 1 hit
PF08033 Sec23_BS, 1 hit
PF04815 Sec23_helical, 1 hit
PF04811 Sec23_trunk, 1 hit
PF04810 zf-Sec23_Sec24, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
SSF81811 SSF81811, 1 hit
SSF82754 SSF82754, 1 hit
SSF82919 SSF82919, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

G3X972-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVNQSAPPV PPYGQNQPIY PGYHQSSYGG QPGPAAPATP YGAYNGPVPG
60 70 80 90 100
YQQAPPQGVP RAPPSSGAPP ASAAQVPCGQ TTYGQFGQGD IQNGPSSTAQ
110 120 130 140 150
MQRVPGSQQF GPPLAPVVSQ PAVLQPYGPP PTSTQVTAQL AGMQISGAVA
160 170 180 190 200
QAPPPSGLGY GPPTSLASAS GNFPNSGPYG SYPQSQAPPL SQAQGHPGVQ
210 220 230 240 250
PPLRSAPPLA SSFTSPASGG PQMPSMTGLL PPGQGFGSLP VNQANHVSSP
260 270 280 290 300
PAPALPPGTQ MTGPPVPPPP PMHSPQQPGY QLQQNGSFGP ARGPQPNYES
310 320 330 340 350
PYPGAPTFGS QPGPPQPLPP KRLDPDAIPS PIQVIEDDRN NRGSEPFVTG
360 370 380 390 400
VRGQVPPLVT TNFLVKDQGN ASPRYIRCTS YNIPCTSDMA KQAQVPLAAV
410 420 430 440 450
IKPLARLPPE EASPYVVDHG ESGPLRCNRC KAYMCPLMTF IEGGRRFQCS
460 470 480 490 500
FCSCVNDVPP QYFQHLDHTG KRVDAYDRPE LSLGSYEFLA TVDYCKNNKF
510 520 530 540 550
PSPPAFIFMI DVSYNAIRTG LVRLLCEELK SLLDYLPREG GAEESAIRVG
560 570 580 590 600
FVTYNKVLHF YNVKSSLAQP QMMVVSDVAD MFVPLLDGFL VNVSESRAVI
610 620 630 640 650
TSLLDQIPEM FADTRETETV FAPVIQAGME ALKAAECAGK LFLFHTSLPI
660 670 680 690 700
AEAPGKLKNR DDRKLINTDK EKTLFQPQTG TYQTLAKECV AQGCCVDLFL
710 720 730 740 750
FPNQYVDVAT LSVVPQLTGG SVYKYACFQV ENDQERFLSD LRRDVQKVVG
760 770 780 790 800
FDAVMRVRTS TGIRAVDFFG AFYMSNTTDV ELAGLDGDKT VTVEFKHDDR
810 820 830 840 850
LNEENGALLQ CALLYTSCAG QRRLRIHNLA LNCCTQLADL YRNCETDTLI
860 870 880 890 900
NYMAKFAYRA VLNSPVKTVR DTLITQCAQI LACYRKNCAS PSSAGQLILP
910 920 930 940 950
ECMKLLPVYL NCVLKSDVLQ PGAEVTTDDR AYVRQLVSSM DVAETNVFFY
960 970 980 990 1000
PRLLPLTKSP LDSTAEPPAV RASEERLSSG DIYLLENGLN LFVWVGASVQ
1010 1020 1030 1040 1050
QGVVQSLFNV SSFSQITSGL SVLPVLDNPL SKKVRGLIDS LRAQRMRYMK
1060 1070 1080 1090
LIVVKQEDKL EMLFKHFLVE DKSLSGGASY VDFLCHMHKE IRQLLS
Length:1,096
Mass (Da):118,581
Last modified:November 16, 2011 - v1
Checksum:iC614860FB9EDE158
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YDI8A0A286YDI8_MOUSE
Sec24-related gene family, member C...
Sec24c
1,020Annotation score:
A0A286YD08A0A286YD08_MOUSE
Sec24-related gene family, member C...
Sec24c
174Annotation score:
A0A286YDJ8A0A286YDJ8_MOUSE
Sec24-related gene family, member C...
Sec24c
119Annotation score:
A0A286YCX0A0A286YCX0_MOUSE
Sec24-related gene family, member C...
Sec24c
71Annotation score:
A0A286YCC8A0A286YCC8_MOUSE
Sec24-related gene family, member C...
Sec24c
168Annotation score:
A0A286YDN4A0A286YDN4_MOUSE
Sec24-related gene family, member C...
Sec24c
90Annotation score:
A0A2I3BQS4A0A2I3BQS4_MOUSE
Sec24-related gene family, member C...
Sec24c
239Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121599 Genomic DNA No translation available.
CH466613 Genomic DNA Translation: EDL01498.1
RefSeqiNP_766184.2, NM_172596.2
UniGeneiMm.173119

Genome annotation databases

EnsembliENSMUST00000048657; ENSMUSP00000045955; ENSMUSG00000039367
GeneIDi218811
UCSCiuc007skg.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121599 Genomic DNA No translation available.
CH466613 Genomic DNA Translation: EDL01498.1
RefSeqiNP_766184.2, NM_172596.2
UniGeneiMm.173119

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiG3X972, 61 interactors
G3X972, 61 interactors
STRINGi10090.ENSMUSP00000045955

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000048657; ENSMUSP00000045955; ENSMUSG00000039367
GeneIDi218811
UCSCiuc007skg.2 mouse

Organism-specific databases

CTDi9632
MGIiMGI:1919746 Sec24c

Phylogenomic databases

eggNOGiKOG1985 Eukaryota
COG5028 LUCA
GeneTreeiENSGT00590000082962
OrthoDBiEOG091G0288
TreeFamiTF300464

Enzyme and pathway databases

ReactomeiR-MMU-204005 COPII-mediated vesicle transport
R-MMU-2132295 MHC class II antigen presentation
R-MMU-5694530 Cargo concentration in the ER
R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Miscellaneous databases

ChiTaRSiSec24c mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039367 Expressed in 290 organ(s), highest expression level in small intestine

Family and domain databases

Gene3Di3.40.20.10, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR036180 Gelsolin-like_dom_sf
IPR006900 Sec23/24_helical_dom
IPR036175 Sec23/24_helical_dom_sf
IPR006896 Sec23/24_trunk_dom
IPR012990 Sec23_24_beta_S
IPR036465 vWFA_dom_sf
IPR006895 Znf_Sec23_Sec24
IPR036174 Znf_Sec23_Sec24_sf
PfamiView protein in Pfam
PF00626 Gelsolin, 1 hit
PF08033 Sec23_BS, 1 hit
PF04815 Sec23_helical, 1 hit
PF04811 Sec23_trunk, 1 hit
PF04810 zf-Sec23_Sec24, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
SSF81811 SSF81811, 1 hit
SSF82754 SSF82754, 1 hit
SSF82919 SSF82919, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3X972_MOUSE
AccessioniPrimary (citable) accession number: G3X972
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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