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Protein
Submitted name:

DEAH (Asp-Glu-Ala-His) box polypeptide 16

Gene

Dhx16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-72163 mRNA Splicing - Major Pathway

Names & Taxonomyi

Protein namesi
Submitted name:
DEAH (Asp-Glu-Ala-His) box polypeptide 16Imported
Submitted name:
DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_aImported
Gene namesi
Name:Dhx16Imported
ORF Names:mCG_141148Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1916442 Dhx16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000024422 Expressed in 291 organ(s), highest expression level in embryonic stem cell

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025292

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini412 – 576Helicase ATP-bindingInterPro annotationAdd BLAST165
Domaini601 – 774Helicase C-terminalInterPro annotationAdd BLAST174

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili80 – 100Sequence analysisAdd BLAST21
Coiled coili117 – 137Sequence analysisAdd BLAST21
Coiled coili201 – 221Sequence analysisAdd BLAST21
Coiled coili232 – 259Sequence analysisAdd BLAST28
Coiled coili265 – 285Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0925 Eukaryota
COG1643 LUCA
GeneTreeiENSGT00910000144017
KOiK12813
OMAiVYNQWVE
OrthoDBiEOG091G030Q
TreeFamiTF313473

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR011709 DUF1605
IPR007502 Helicase-assoc_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF04408 HA2, 1 hit
PF00271 Helicase_C, 1 hit
PF07717 OB_NTP_bind, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00847 HA2, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G3X8X0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATPAGLERW VQEELHSVLG LSERHVAQFL IGTAQRCASA EEFVQRLRDT
60 70 80 90 100
DTLDLGGPAR DFALKLWSKV PRKAVVEKPA RAAEREARAL LEKNRSYKLL
110 120 130 140 150
EDSESGEEAV GSNGSSLQKK RKRRKHLRKK HQEDEEDEEE EVSESGKRKA
160 170 180 190 200
GGSKSPTEEK PASEDEWERT ERERLQDLEE RDAFAERVRQ RDKDRTRNVL
210 220 230 240 250
ERSDKKAYEE AQKRLKMAEE DRKAMVPELR KKSRREYLAK REREKLEDLE
260 270 280 290 300
AELADEEVLF GDVELSRHER RELKYKRRVR DLAREYRAAG EQEKLEATNR
310 320 330 340 350
YHMPKETRGQ PARTVDIVEE ESGAPGEEQR RWEEAQLGAA SLKFGARDAA
360 370 380 390 400
AQEAKYQLVL EEDETIEFVR AAQLQGDEEP SGPPLSAQAQ QKESIQAVRR
410 420 430 440 450
SLPVFPFREE LLAAIANHQV LIIEGETGSG KTTQIPQYLF EEGYTKKGMK
460 470 480 490 500
IACTQPRRVA AMSVAARVAR EMGVKLGNEV GYSIRFEDCT SERTVLRYMT
510 520 530 540 550
DGMLLREFLS EPDLASYSVV MVDEAHERTL HTDILFGLIK DVARFRPELK
560 570 580 590 600
VLVASATLDT ARFSAFFDDA PVFRIPGRRF PVDIFYTKAP EADYLEACVV
610 620 630 640 650
SVLQIHVTQP PGDILVFLTG QEEIEAACEM LQDRCRRLGS KIRELLVLPI
660 670 680 690 700
YANLPSDMQA RIFQPTPPGA RKVVVATNIA ETSLTIEGII YVLDPGFCKQ
710 720 730 740 750
KSYNPRTGME SLTVTPCSKA SANQRAGRAG RVAAGKCFRL YTAWAYQHEL
760 770 780 790 800
EETTVPEIQR TSLGNVVLLL KSLGIHDLMH FDFLDPPPYE TLLLALEQLY
810 820 830 840 850
ALGALNHLGE LTTSGRKMAE LPVDPMLSKM ILASEKYSCS EEILTVAAML
860 870 880 890 900
SVNNSIFYRP KDKVVHADNA RVNFFLPGGD HLVLLNVYTQ WAESGYSSQW
910 920 930 940 950
CYENFVQFRS MRRARDVREQ LEGLLERVEV GLTSCQGDYV RVRKAITSGY
960 970 980 990 1000
FYHTARLTRS GYRTVKQQQT VFIHPNSSLF EQQPRWLLYH ELVLTTKEFM
1010 1020 1030 1040
RQVLEIESSW LLEVAPHYYK AKELEDPHAK KMPKKVGKTR EELG
Length:1,044
Mass (Da):119,072
Last modified:November 16, 2011 - v1
Checksum:i616D2531D70CD324
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q05BH3Q05BH3_MOUSE
DEAH (Asp-Glu-Ala-His) box polypept...
Dhx16
741Annotation score:
G3UXT5G3UXT5_MOUSE
DEAH (Asp-Glu-Ala-His) box polypept...
Dhx16
123Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974451 Genomic DNA No translation available.
CH466559 Genomic DNA Translation: EDL23242.1
RefSeqiNP_081263.2, NM_026987.2
UniGeneiMm.390986

Genome annotation databases

EnsembliENSMUST00000025292; ENSMUSP00000025292; ENSMUSG00000024422
GeneIDi69192
KEGGimmu:69192
UCSCiuc008ciw.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974451 Genomic DNA No translation available.
CH466559 Genomic DNA Translation: EDL23242.1
RefSeqiNP_081263.2, NM_026987.2
UniGeneiMm.390986

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025292

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025292; ENSMUSP00000025292; ENSMUSG00000024422
GeneIDi69192
KEGGimmu:69192
UCSCiuc008ciw.2 mouse

Organism-specific databases

CTDi8449
MGIiMGI:1916442 Dhx16

Phylogenomic databases

eggNOGiKOG0925 Eukaryota
COG1643 LUCA
GeneTreeiENSGT00910000144017
KOiK12813
OMAiVYNQWVE
OrthoDBiEOG091G030Q
TreeFamiTF313473

Enzyme and pathway databases

ReactomeiR-MMU-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024422 Expressed in 291 organ(s), highest expression level in embryonic stem cell

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR011709 DUF1605
IPR007502 Helicase-assoc_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF04408 HA2, 1 hit
PF00271 Helicase_C, 1 hit
PF07717 OB_NTP_bind, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00847 HA2, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3X8X0_MOUSE
AccessioniPrimary (citable) accession number: G3X8X0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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