Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Calcineurin binding protein 1, isoform CRA_a

Gene

Cabin1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Names & Taxonomyi

Protein namesi
Submitted name:
Calcineurin binding protein 1, isoform CRA_aImported
Submitted name:
Calcineurin-binding protein 1Imported
Gene namesi
Name:Cabin1Imported
ORF Names:mCG_117500Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1298375 Cabin1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000020196 Expressed in 222 organ(s), highest expression level in mesenteric lymph node

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiG3X8Q1, 2 interactors
STRINGi10090.ENSMUSP00000001712

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 157TPR_REGIONInterPro annotationAdd BLAST68
Repeati90 – 123TPRPROSITE-ProRule annotationAdd BLAST34
Repeati124 – 157TPRPROSITE-ProRule annotationAdd BLAST34
Repeati615 – 648TPRPROSITE-ProRule annotationAdd BLAST34
Domaini1055 – 1088TPR_REGIONInterPro annotationAdd BLAST34
Repeati1055 – 1088TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili96 – 116Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IFFG Eukaryota
ENOG410XY91 LUCA
GeneTreeiENSGT00390000008529
KOiK17613
OMAiAEPTCSQ
OrthoDBiEOG091G008Y
TreeFamiTF323227

Family and domain databases

CDDicd13839 MEF2_binding, 1 hit
Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR033053 Hir3/CABIN1
IPR015134 MEF2-bd
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR15502 PTHR15502, 1 hit
PfamiView protein in Pfam
PF09047 MEF2_binding, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

G3X8Q1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIRIAALNAS STIEDDHEGS FKSHKIQTKE AQEAEAFALY HKALDLQKHD
60 70 80 90 100
RFEESAKAYH ELLEARLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA
110 120 130 140 150
AQREDLETAM EFYLEAVMLD STDVNLWYKI GHVALRLIRL PLARHAFEEG
160 170 180 190 200
LRCNPDHWPC LDNLITVLYT LSDYTTCLYF ICKALEKDCR YSKGLVLKEK
210 220 230 240 250
IFEEQPCLRK DSLRMFLKCD MSIHDVSVSA AETQAIVDEA LGLRKKRQAL
260 270 280 290 300
IVREKEPDLK LVQPIPFFTW KCLGESLLAM YSHLTTCEPP RPSLGKRIDL
310 320 330 340 350
SDYQDPSQLL ASSVVVTPVS VVQPSPICTN PTVAVAEPVL SYTSVTAASF
360 370 380 390 400
PLHSPSLLDT GTPMGDVSGG DKSKKGVKRK KTVEESGETA KRRSARVRNT
410 420 430 440 450
KCKKEEKVDF QGLLVKFLPS RLRKLDPEEE DDPFNNYEVQ AEAKLESFSN
460 470 480 490 500
VGPHRLSFDS ATFMESEKQD VHAFLMENLT NGGLLELMMR YLKSMGHKFL
510 520 530 540 550
LKWPPGLADV VLSVYHSWRR HSTSLPNPLL RDCSNKHIKD MMLMSLSCME
560 570 580 590 600
LQLDQWLLTK GRSSAVSPRN CPAGVVTGRF GPDFPGTHCL GDLLQLSFAS
610 620 630 640 650
SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEILQSSSA
660 670 680 690 700
IQAQAGAEQG DIVIRLPNLH NDSVVSLEEI DKNLKSLERC QSLEEIQRLF
710 720 730 740 750
EAGDYKAVVH LLRPTLCTSG FDRAKHLEFM TSIPERPAQL LLLQDSLLRL
760 770 780 790 800
KDHRQCFECS DVALNEAVQQ MLNSSESAAK EEWVATVTQL LLGIEQALSS
810 820 830 840 850
DSSGSILKES SSTTGLVRLT NNLIQVIDCS MAVQEEPKEP YVSSVLPWII
860 870 880 890 900
LHRIIWQEED TFRSLCHQQQ LQNPTEEGIP EMPMLPSSLM LLNTAHEYLG
910 920 930 940 950
RRSWCCNSDG ALLRFYVQVL QKELAASASE DTHPYKEELE TALEQCFYCL
960 970 980 990 1000
YSFPSKKSKA RYLEEHSAQQ VDLIWEDALF MFEYFKPKTL PEFDSYKTST
1010 1020 1030 1040 1050
VSADLANLLK RIATIVPRTE KPALSMDKVS AYIEGTSAEA PCLPEGADPT
1060 1070 1080 1090 1100
PPVLNELYYL LADYHFKNKE QSKAIKFYMH DICICPNRFD SWAGMALARA
1110 1120 1130 1140 1150
SRIQDKLNSN ELKSDGPIWK HATPVLNCFR RALEIDSSNL SLWIEYGTMS
1160 1170 1180 1190 1200
YALHSFASRQ LKQWRSELPP ELVQQMEDRR DSMLETARHC FTSAARCEGD
1210 1220 1230 1240 1250
GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY
1260 1270 1280 1290 1300
HNPPELAMEA LEVYFRLHAS ILKLLGKPDS GVGAEVLVSF MKEAAEGPFA
1310 1320 1330 1340 1350
RGEEKNTPKA SEKEKACLVD EDSHSSAGTL PGPGASLPSS SGPGLTSPPY
1360 1370 1380 1390 1400
TATPIDHDYV KCKKPHQQAA PDDRSQDSTA VALSDSSSTQ DFFNEPTSLL
1410 1420 1430 1440 1450
EGSRKLFPEK RLSGLSAQAG PSGKDLPGPT EERGKTEESL ESTEAFRVVE
1460 1470 1480 1490 1500
QSVQKPVADS SASAYIPSKP PASTPPLWDG KKRGDSLGEP VAFPQGLPAG
1510 1520 1530 1540 1550
AEEQRQFLTE QCISSFCLCL SRFPQHYKSL YRLAFLYTYS KTHRNLQWAR
1560 1570 1580 1590 1600
DVLLGSSIPW QQLQHMPAQG LFCERNKTNF FNGIWRIPVD EIDRPGSFAW
1610 1620 1630 1640 1650
HMNRSIVLLL KVLAQLRDHS TLLKVSSMLQ RTPDQGKKYL RDADRQVLAQ
1660 1670 1680 1690 1700
RAFILTVKVL EDTLSELAEG SEHPGSKACG LSGARMTTDV SHKASPEDGQ
1710 1720 1730 1740 1750
ESPQHPKKLP LADGSGPGPE PGGRMGPLNQ LPVVTDIRDN TDQGGEQKDK
1760 1770 1780 1790 1800
ESPQVGPTEP MDTSEAAGRH SDLEQTSRLL PGRPPRDRGP ESRSAELSLE
1810 1820 1830 1840 1850
ELSISTRQQP APLAPSPAAP TTTAAPTTMA ARGAGHSEEA PPRPNRKRKL
1860 1870 1880 1890 1900
LEDTESGKTL LLDAYRVWQQ GQKGMAYDLS RIEKIMSETY MLIKQVDEET
1910 1920 1930 1940 1950
ALEQAVKFCQ VHLGAATQRQ ASGDTPTTPK HPKDSRENFF PATVVPTVPD
1960 1970 1980 1990 2000
PTAPDALQRP SDSHLKPVLA TVITCPPSAS ASIPDLSTDP GIPRPHRPET
2010 2020 2030 2040 2050
TPSRAPLSPE GEEASGVTEG TSILPQEPRY SHQIKMAATG HLAEQHCWPV
2060 2070 2080 2090 2100
EVACQTGAEP TCSQASSTKV PSSGSTQTAE SHQGKTESSR AKSRLLPNMP
2110 2120 2130 2140 2150
KLVIPSATTK SPPEITVTPP TPTLLSPKGS ISEETKQKLK SAILSAQSAA
2160 2170 2180
NVRKESLCQP ALEVLETSSQ ESSLESETDE DDDFMDV
Length:2,187
Mass (Da):243,172
Last modified:November 16, 2011 - v1
Checksum:i099341987D3BFC85
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1W2P8C4A0A1W2P8C4_MOUSE
Calcineurin-binding protein 1
Cabin1
473Annotation score:
A0A1W2P819A0A1W2P819_MOUSE
Calcineurin-binding protein 1
Cabin1
191Annotation score:
A0A1W2P8A1A0A1W2P8A1_MOUSE
Calcineurin-binding protein 1
Cabin1
18Annotation score:
A0A1W2P6X4A0A1W2P6X4_MOUSE
Calcineurin-binding protein 1
Cabin1
39Annotation score:
A0A1W2P755A0A1W2P755_MOUSE
Calcineurin-binding protein 1
Cabin1
32Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087540 Genomic DNA No translation available.
AC142499 Genomic DNA No translation available.
CH466553 Genomic DNA Translation: EDL31891.1
RefSeqiNP_766137.2, NM_172549.3
XP_006513082.1, XM_006513019.3
UniGeneiMm.257404
Mm.491062

Genome annotation databases

EnsembliENSMUST00000001712; ENSMUSP00000001712; ENSMUSG00000020196
GeneIDi104248
KEGGimmu:104248
UCSCiuc007fqx.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087540 Genomic DNA No translation available.
AC142499 Genomic DNA No translation available.
CH466553 Genomic DNA Translation: EDL31891.1
RefSeqiNP_766137.2, NM_172549.3
XP_006513082.1, XM_006513019.3
UniGeneiMm.257404
Mm.491062

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiG3X8Q1, 2 interactors
STRINGi10090.ENSMUSP00000001712

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000001712; ENSMUSP00000001712; ENSMUSG00000020196
GeneIDi104248
KEGGimmu:104248
UCSCiuc007fqx.1 mouse

Organism-specific databases

CTDi23523
MGIiMGI:1298375 Cabin1

Phylogenomic databases

eggNOGiENOG410IFFG Eukaryota
ENOG410XY91 LUCA
GeneTreeiENSGT00390000008529
KOiK17613
OMAiAEPTCSQ
OrthoDBiEOG091G008Y
TreeFamiTF323227

Enzyme and pathway databases

ReactomeiR-MMU-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Miscellaneous databases

ChiTaRSiCabin1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020196 Expressed in 222 organ(s), highest expression level in mesenteric lymph node

Family and domain databases

CDDicd13839 MEF2_binding, 1 hit
Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR033053 Hir3/CABIN1
IPR015134 MEF2-bd
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR15502 PTHR15502, 1 hit
PfamiView protein in Pfam
PF09047 MEF2_binding, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiG3X8Q1_MOUSE
AccessioniPrimary (citable) accession number: G3X8Q1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again