Uncharacterized protein

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• DNA-binding transcription factor activity, RNA polymerase II-specific Source: Ensembl
• identical protein binding Source: Ensembl
• RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl

GO - Biological processⁱ

• cell motility Source: Ensembl
• PML body organization Source: Ensembl
• positive regulation of angiogenesis Source: Ensembl
• positive regulation of blood vessel endothelial cell migration Source: Ensembl
• positive regulation of erythrocyte differentiation Source: Ensembl
• positive regulation of inflammatory response Source: Ensembl
• positive regulation of leukocyte adhesion to vascular endothelial cell Source: Ensembl
• positive regulation of transcription by RNA polymerase II Source: Ensembl
• pri-miRNA transcription by RNA polymerase II Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• identical protein binding Source: Ensembl

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MKAAVDLKPT LTIIKTEKVD LELLPSPDME CADVPLLTPS SKEMMSQALK 
        60         70         80         90        100
ATFSGFTKEQ QRLGIPKDPR QWTETHVRDW VLWAVNEFSL KGVNFQKFCM 
       110        120        130        140        150
SGAALCALGK DCFLELAPDF VGDILWEHLE ILQKEDMKPY QVSGVSSAYP 
       160        170        180        190        200
ETRYTSDYFI SYGIEHAQCV PPSEFSEPSF ITESYQTLHP ISSEELLSLK 
       210        220        230        240        250
YENDYSSVIL SRDPLQADTL STDYFTIKQE VVTPDNMCMG RTSRGKLGGQ 
       260        270        280        290        300
DSFESIESYE SCDRLTQSWS SQSSFNSLQR VPSYDSFDSE DYPAALPNHK 
       310        320        330        340        350
PKGTFKDYVR DRAELNKDKP VIPAAALAGY TGSGPIQLWQ FLLELLTDKS 
       360        370        380        390        400
CQSFISWTGD GWEFKLSDPD EVARRWGKRK NKPKMNYEKL SRGLRYYYDK 
       410        420        430        440 
NIIHKTAGKR YVYRFVCDLQ SLLGYTPEEL HAMLDVKPDA DE         

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ