UniProtKB - G3WGZ1 (G3WGZ1_SARHA)
Protein
Mothers against decapentaplegic homolog
Gene
N/A
Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
- transforming growth factor beta receptor signaling pathway Source: InterPro
Keywordsi
Molecular function | DNA-bindingUniRule annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Ligand | Metal-bindingARBA annotation, ZincARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Mothers against decapentaplegic homologUniRule annotationShort name: MAD homologUniRule annotation Short name: Mothers against DPP homologUniRule annotation Alternative name(s): SMAD family memberUniRule annotation |
Organismi | Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported |
Taxonomic identifieri | 9305 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Metatheria › Dasyuromorphia › Dasyuridae › Sarcophilus |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-SubCell
- transcription regulator complex Source: InterPro
Keywords - Cellular componenti
CytoplasmUniRule annotation, NucleusUniRule annotationARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 81 | MH1InterPro annotationAdd BLAST | 81 | |
Domaini | 178 – 367 | MH2InterPro annotationAdd BLAST | 190 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 112 – 154 | DisorderedSequence analysisAdd BLAST | 43 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG3701, Eukaryota |
GeneTreei | ENSGT00940000153499 |
HOGENOMi | CLU_026736_0_0_1 |
InParanoidi | G3WGZ1 |
OMAi | NPVSPAH |
TreeFami | TF314923 |
Family and domain databases
Gene3Di | 2.60.200.10, 1 hit 3.90.520.10, 1 hit |
InterProi | View protein in InterPro IPR013790, Dwarfin IPR003619, MAD_homology1_Dwarfin-type IPR013019, MAD_homology_MH1 IPR017855, SMAD-like_dom_sf IPR001132, SMAD_dom_Dwarfin-type IPR008984, SMAD_FHA_dom_sf IPR036578, SMAD_MH1_sf |
PANTHERi | PTHR13703, PTHR13703, 1 hit |
Pfami | View protein in Pfam PF03165, MH1, 1 hit PF03166, MH2, 1 hit |
SMARTi | View protein in SMART SM00523, DWA, 1 hit SM00524, DWB, 1 hit |
SUPFAMi | SSF49879, SSF49879, 1 hit SSF56366, SSF56366, 1 hit |
PROSITEi | View protein in PROSITE PS51075, MH1, 1 hit PS51076, MH2, 1 hit |
i Sequence
Sequence statusi: Complete.
G3WGZ1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
PSLNLNSDFF FLHRSLDGRL QVSHRKGLPH VIYCRLWRWP DLHSHHELRA
60 70 80 90 100
MEMCEFAFNM KKDEVCVNPY HYQRVETPVL PPVLVPRHTE IPAEFPPLDD
110 120 130 140 150
YSHSIPENTN FPAGIEPQSN YIPETPPPGY LSEDGETSDH QMNHSMDAGS
160 170 180 190 200
PNLSPNPMSP AHNNLDLQPV TYCEPAFWCS ISYYELNQRV GETFHASQPS
210 220 230 240 250
MTVDGFTDPS NSERFCLGLL SNVNRNAAVE LTRRHIGQKL DFWLTPFCIC
260 270 280 290 300
ICCSALFQFY GTGYTLYWIR DNILVLLAGC NLKIFNNQEF AALLAQSVNQ
310 320 330 340 350
GFEAVYQLTR MCTIRMSFVK GWGAEYRRQT VTSTPCWIEL HLNGPLQWLD
360
KVLTQMGSPS IRCSSVS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEFK01007959 Genomic DNA No translation available. AEFK01007960 Genomic DNA No translation available. AEFK01007961 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSSHAT00000014820; ENSSHAP00000014696; ENSSHAG00000012543 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEFK01007959 Genomic DNA No translation available. AEFK01007960 Genomic DNA No translation available. AEFK01007961 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9305.ENSSHAP00000014696 |
Genome annotation databases
Ensembli | ENSSHAT00000014820; ENSSHAP00000014696; ENSSHAG00000012543 |
Phylogenomic databases
eggNOGi | KOG3701, Eukaryota |
GeneTreei | ENSGT00940000153499 |
HOGENOMi | CLU_026736_0_0_1 |
InParanoidi | G3WGZ1 |
OMAi | NPVSPAH |
TreeFami | TF314923 |
Family and domain databases
Gene3Di | 2.60.200.10, 1 hit 3.90.520.10, 1 hit |
InterProi | View protein in InterPro IPR013790, Dwarfin IPR003619, MAD_homology1_Dwarfin-type IPR013019, MAD_homology_MH1 IPR017855, SMAD-like_dom_sf IPR001132, SMAD_dom_Dwarfin-type IPR008984, SMAD_FHA_dom_sf IPR036578, SMAD_MH1_sf |
PANTHERi | PTHR13703, PTHR13703, 1 hit |
Pfami | View protein in Pfam PF03165, MH1, 1 hit PF03166, MH2, 1 hit |
SMARTi | View protein in SMART SM00523, DWA, 1 hit SM00524, DWB, 1 hit |
SUPFAMi | SSF49879, SSF49879, 1 hit SSF56366, SSF56366, 1 hit |
PROSITEi | View protein in PROSITE PS51075, MH1, 1 hit PS51076, MH2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3WGZ1_SARHA | |
Accessioni | G3WGZ1Primary (citable) accession number: G3WGZ1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | February 10, 2021 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |