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Entry version 81 (26 Feb 2020)
Sequence version 1 (16 Nov 2011)
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Protein

Tyrosine-protein phosphatase non-receptor type 13

Gene

Ptpn13

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei2349SubstrateUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei2379Phosphocysteine intermediateUniRule annotation1
Binding sitei2423SubstrateUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphataseUniRule annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-1660499 Synthesis of PIPs at the plasma membrane

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tyrosine-protein phosphatase non-receptor type 13UniRule annotation (EC:3.1.3.48UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ptpn13Imported
ORF Names:rCG_37921Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Rat genome database

More...
RGDi
1563360 Ptpn13

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000002061 Expressed in lung and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000057876

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 190KINDInterPro annotationAdd BLAST188
Domaini565 – 865FERMInterPro annotationAdd BLAST301
Domaini1084 – 1170PDZInterPro annotationAdd BLAST87
Domaini1357 – 1442PDZInterPro annotationAdd BLAST86
Domaini1491 – 1579PDZInterPro annotationAdd BLAST89
Domaini1766 – 1847PDZInterPro annotationAdd BLAST82
Domaini1868 – 1944PDZInterPro annotationAdd BLAST77
Domaini2184 – 2438Tyrosine-protein phosphataseInterPro annotationAdd BLAST255
Domaini2360 – 2429TYR_PHOSPHATASE_2InterPro annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni183 – 225DisorderedSequence analysisAdd BLAST43
Regioni248 – 281DisorderedSequence analysisAdd BLAST34
Regioni429 – 461DisorderedSequence analysisAdd BLAST33
Regioni944 – 966DisorderedSequence analysisAdd BLAST23
Regioni1007 – 1065DisorderedSequence analysisAdd BLAST59
Regioni1167 – 1354DisorderedSequence analysisAdd BLAST188
Regioni1439 – 1475DisorderedSequence analysisAdd BLAST37
Regioni1603 – 1657DisorderedSequence analysisAdd BLAST55
Regioni1688 – 1707DisorderedSequence analysisAdd BLAST20
Regioni1971 – 2029DisorderedSequence analysisAdd BLAST59
Regioni2054 – 2139DisorderedSequence analysisAdd BLAST86
Regioni2379 – 2385Substrate bindingUniRule annotation7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili464 – 491Sequence analysisAdd BLAST28
Coiled coili859 – 879Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi188 – 208PolyampholyteSequence analysisAdd BLAST21
Compositional biasi248 – 269PolyampholyteSequence analysisAdd BLAST22
Compositional biasi442 – 461PolarSequence analysisAdd BLAST20
Compositional biasi946 – 961PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1007 – 1023PolarSequence analysisAdd BLAST17
Compositional biasi1049 – 1063PolarSequence analysisAdd BLAST15
Compositional biasi1189 – 1203PolarSequence analysisAdd BLAST15
Compositional biasi1228 – 1255PolarSequence analysisAdd BLAST28
Compositional biasi1263 – 1295PolarSequence analysisAdd BLAST33
Compositional biasi1313 – 1335PolarSequence analysisAdd BLAST23
Compositional biasi1603 – 1634PolarSequence analysisAdd BLAST32
Compositional biasi1635 – 1656PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2008 – 2024PolyampholyteSequence analysisAdd BLAST17
Compositional biasi2112 – 2139PolyampholyteSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0792 Eukaryota
COG5599 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155133

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000906_0_0_1

KEGG Orthology (KO)

More...
KOi
K02374

Identification of Orthologs from Complete Genome Data

More...
OMAi
HQVIYIS

Database of Orthologous Groups

More...
OrthoDBi
411281at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315388

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473 FERM_B-lobe, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
2.30.29.30, 1 hit
3.90.190.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019749 Band_41_domain
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR011019 KIND_dom
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR012153 PTPN13
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
IPR029071 Ubiquitin-like_domsf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00595 PDZ, 5 hits
PF00102 Y_phosphatase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000933 Tyr-Ptase_nr13, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00935 BAND41
PR00700 PRTYPHPHTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295 B41, 1 hit
SM01196 FERM_C, 1 hit
SM00750 KIND, 1 hit
SM00228 PDZ, 5 hits
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031 SSF47031, 1 hit
SSF50156 SSF50156, 5 hits
SSF52799 SSF52799, 1 hit
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50057 FERM_3, 1 hit
PS51377 KIND, 1 hit
PS50106 PDZ, 5 hits
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3V9S3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHVSLAEALE VRGGPLQEEE IWAVLNQSAE SLQEVFRRVS IADPAALGFI
60 70 80 90 100
ISPWSLLLLP SGSVSFTDEN VCSQDLRAFT APEVLQSHSL TSLSDVEKVH
110 120 130 140 150
IYSLGMTLYW GADHEVPQSQ PIKLGDHLNS ILLGMCEDVL YARVSVRTVL
160 170 180 190 200
DACSAHIRNS NCAPSFSYVK QLVKLVLGNI SGTDPLSHSS EEKPDRSQAI
210 220 230 240 250
RDRLRGKGLP IGRSSTSDAL DTHKAPLSQQ TFLNKGLSKS MGFLSVRDTQ
260 270 280 290 300
EEEDYSKEIP SDNNSRHEDS EPFSSPYQFK TSSPHIDVLS KKKTWASSMD
310 320 330 340 350
LLCAADRDLS GEIGRYQHCD PETGTGRTSI TSRKKEGRYS DGSIALDVFG
360 370 380 390 400
PQKAEPVIHS RELPASSAVS SALDRIRERQ KKLQVLREAM NVEEPVRRYK
410 420 430 440 450
TYHSDLFSTS SESPSIISSD SDFRQVRKSE ASKRFESSSG LPGVDDTVQS
460 470 480 490 500
RPSRQYETSL EGSLINQEMM LRRQEEEMMQ LQARMALRQS RLSLYPGDTI
510 520 530 540 550
KTSMLDISRD PLREMALETA MTQRKLRNFF GPEFVKTTVE PFASLDLPRS
560 570 580 590 600
ILLQTKKGKS EEQRKKVNIM LLSGQRLELT CDTKTVCRDV FDMVVAHIGL
610 620 630 640 650
VEHHLFALAT LKENEYFFVD PDLKLTKVAP EGWKEEPKRK GKAAVDFTLF
660 670 680 690 700
FRIKFFMDDV SLIQHSLTCH QYYLQLRKDL LEERIHCDDE ASLLLASLAL
710 720 730 740 750
QAEYGDYQPE VHGLSYFRLE HYLPARVMEK LDMSYIKEEL PKLHNTYAGA
760 770 780 790 800
SEKETELEFL KVCQRLTEYG VHFHRVHPEK KSQTGILLGV CSKGVLVFEV
810 820 830 840 850
HNGVRALVLR FPWRETKKIS FSKKKITLQN TSDGIKHAFQ TDSSKACQYL
860 870 880 890 900
LQLCSSQHKF QLQMRARQSN QDAQDLERAS FRSLNLQAES VRGFNVGRAI
910 920 930 940 950
STGSLASSTF NKLAVRPLSV QAEILKRLSC SEWSLYQPLQ NSSKEKNDKA
960 970 980 990 1000
SWEEKPRGMS KSYHDLSQAS LCPHRKQVIN MESLPQAFAE LVGKPLYPMA
1010 1020 1030 1040 1050
RSDTESLAGL PQLNNSKSVA SLNRSPERRS HESDSSVEDP GQAYVVGMSL
1060 1070 1080 1090 1100
PSSGKSSSQV PFKDNDSLHK RWSTVSSPER EITLVNLKKD LKHGLGFQIV
1110 1120 1130 1140 1150
GGGKMGRLDL GVFISAVTPG GPADLDGCLK PGDRLISVNS VSLEGVSHHA
1160 1170 1180 1190 1200
AVDILQNAPE DVTLVISQPK EKPTKVPSTP VHFANGMKNY TKKPSSMQDS
1210 1220 1230 1240 1250
AMDPSEDQPW PRGPLRHVPE SPFGLSSGLR EGSLSSQDSR TESASLSQSH
1260 1270 1280 1290 1300
VNGFFTSHLG DRGWQEPQHS SPSPPVTSKI TEKTFSDSYR SPARRQGTCD
1310 1320 1330 1340 1350
VTELPGCADS DIDDPTYSSS QDRQAPKQEP SSPLKASDKM SFAAFPGPSP
1360 1370 1380 1390 1400
EPGDAFEVEL AKTDGSLGIS VTGGVNTSVR HGGIYVKAVI PNGAAETDGR
1410 1420 1430 1440 1450
IHKGDRVLAV NGVSLEGATH KQAVETLRNT GQVVHLLLEK GQSPTSRERD
1460 1470 1480 1490 1500
PASPRCPTPD QDAQSQAPEK MEKQTAHVKD YSFVTEDNTF EVKLFKNSSG
1510 1520 1530 1540 1550
LGFSFSREDN LTPELINGSI VRVKKLFPGQ PAAESGKINV GDVILKVNGA
1560 1570 1580 1590 1600
PLKGLSQQDV ISALRGTAPE VSLLLCRPAP GVLPEVNTAL LTPLHSPAHA
1610 1620 1630 1640 1650
FLNSRKEHSQ PSPLSVEQCA SSDENGLSGQ SKRQCKPPSR RESYSDHSDS
1660 1670 1680 1690 1700
GEEESVRAAA KMPNVIPLSA FAPEALRSQG EPASTMFYLP RKIPGKPESE
1710 1720 1730 1740 1750
SSRLPHPLDV SPGQIRQPPA ECAPSDSPGK HLTHLASQLH KEENMTALKN
1760 1770 1780 1790 1800
DLGNHLEDSE LEVELLITLV KSEKGSLGFT VTKGSQSIGC YVHDVIQDPA
1810 1820 1830 1840 1850
KGDGRLRPGD RLVKVNDADV TNMTHTDAVN LLRAAPKTVR LVIGRILELP
1860 1870 1880 1890 1900
RMPVFPHLLP DITVTCHGEE LGFSLSGGRG SPHGVVYISD INPRSAAAVD
1910 1920 1930 1940 1950
CSLQLLDIIH YVNGVSTHGM TLEEANRALD LSLPSVVLKV TRDGCPVVPC
1960 1970 1980 1990 2000
STRSAISALR PLEANGLSSM EPYGQPALTP KKSFSKVNGD GASGAMCPGG
2010 2020 2030 2040 2050
KGLSSPRKKS ADLMEARESD SRDDDVYDDP QEAEVIQSLL DVVDEEAQNL
2060 2070 2080 2090 2100
LNQTKASRRA CSPDPLRTNG EASEDGEDTD CDGSPLPEDV PESVNGGGGK
2110 2120 2130 2140 2150
ACFASLIQAS QEEKPVKEEA TQESRESTTE TTDREDSSKD PLFLTNEELA
2160 2170 2180 2190 2200
ALPVVRVPPS GKYTGTQLQA TIRTLQGLLD QGIPSKELEN LQELKPLDQC
2210 2220 2230 2240 2250
LIGQTKENRR KNRYKNILPY DTTRVPLGDE GGYINASFIR IPVGTQEFVY
2260 2270 2280 2290 2300
IACQGPLPTT VGDFWQMVWE QNSTVIAMMT QEVEGEKIKC QRYWPSILGT
2310 2320 2330 2340 2350
TTMANERLRL ALLRMQQLKG FVVRVMALED IQTGEVRHIS HLNFTAWPDH
2360 2370 2380 2390 2400
DTPSHPEDLL TFISYMRHIR RSGPVITHCS AGIGRSGTLI CIDVVLGLIS
2410 2420 2430 2440 2450
QDLEFDISDL VRCMRLQRHG MVQTEGQYVF CYQVVLYVLT HLQAEEQKAQ

PGLPQ
Length:2,455
Mass (Da):270,444
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55B0C80CAD780D7B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07014298 Genomic DNA No translation available.
CH474022 Genomic DNA Translation: EDL99522.1

NCBI Reference Sequences

More...
RefSeqi
NP_001094259.1, NM_001100789.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000061162; ENSRNOP00000057876; ENSRNOG00000002061
ENSRNOT00000087081; ENSRNOP00000071873; ENSRNOG00000002061

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
498331

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:498331

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07014298 Genomic DNA No translation available.
CH474022 Genomic DNA Translation: EDL99522.1
RefSeqiNP_001094259.1, NM_001100789.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057876

Genome annotation databases

EnsembliENSRNOT00000061162; ENSRNOP00000057876; ENSRNOG00000002061
ENSRNOT00000087081; ENSRNOP00000071873; ENSRNOG00000002061
GeneIDi498331
KEGGirno:498331

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5783
RGDi1563360 Ptpn13

Phylogenomic databases

eggNOGiKOG0792 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00940000155133
HOGENOMiCLU_000906_0_0_1
KOiK02374
OMAiHQVIYIS
OrthoDBi411281at2759
TreeFamiTF315388

Enzyme and pathway databases

ReactomeiR-RNO-1660499 Synthesis of PIPs at the plasma membrane

Gene expression databases

BgeeiENSRNOG00000002061 Expressed in lung and 9 other tissues

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
2.30.29.30, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR011019 KIND_dom
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR012153 PTPN13
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00595 PDZ, 5 hits
PF00102 Y_phosphatase, 1 hit
PIRSFiPIRSF000933 Tyr-Ptase_nr13, 1 hit
PRINTSiPR00935 BAND41
PR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM01196 FERM_C, 1 hit
SM00750 KIND, 1 hit
SM00228 PDZ, 5 hits
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF50156 SSF50156, 5 hits
SSF52799 SSF52799, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit
PS51377 KIND, 1 hit
PS50106 PDZ, 5 hits
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3V9S3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3V9S3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 26, 2020
This is version 81 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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