RCG59756

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• bHLH transcription factor binding Source: Ensembl
• E-box binding Source: Ensembl
• protein heterodimerization activity Source: Ensembl
• RNA polymerase II distal enhancer sequence-specific DNA binding Source: Ensembl
• transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding Source: Ensembl

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• BMP signaling pathway Source: Ensembl
• cellular response to mechanical stimulus Source: Ensembl
• cellular response to transforming growth factor beta stimulus Source: Ensembl
• chondrocyte differentiation Source: Ensembl
• collagen fibril organization Source: Ensembl
• deltoid tuberosity development Source: Ensembl
• embryonic skeletal system development Source: Ensembl
• endochondral ossification Source: Ensembl
• face morphogenesis Source: Ensembl
• heart valve formation Source: Ensembl
• mesoderm formation Source: Ensembl
• negative regulation of apoptotic process Source: Ensembl
• negative regulation of transcription, DNA-templated Source: Ensembl
• positive regulation of cartilage development Source: Ensembl
• positive regulation of cell proliferation Source: Ensembl
• positive regulation of collagen biosynthetic process Source: Ensembl
• positive regulation of gastrulation Source: Ensembl
• sclerotome development Source: Ensembl
• skeletal muscle cell differentiation Source: Ensembl
• tendon cell differentiation Source: Ensembl
• tissue homeostasis Source: Ensembl

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• bHLH transcription factor binding Source: Ensembl
• protein heterodimerization activity Source: Ensembl

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MSFAMLRSAP PPGRYLYPEV SPLSEDEDRG SESSGSDEKP CRVHAARCGL 
        60         70         80         90        100
QGARRRAGGR RAAGSGPGPG GRPGREPRQR HTANARERDR TNSVNTAFTA 
       110        120        130        140        150
LRTLIPTEPA DRKLSKIETL RLASSYISHL GNVLLVGEAC GDGQPCHSGP 
       160        170        180        190        200
AFFHSGRAGS PLPPPPPPPP LPLARDGGEN TQPKQICTFC LSNQRKLSKD 

RDRKTAIRS                                              

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ