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UniProtKB - G3V8R7 (G3V8R7_RAT)
Protein
Submitted name:
GATA zinc finger domain-containing 2A
Gene
Gatad2a
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- protein-macromolecule adaptor activity Source: RGD
GO - Biological processi
- anterior neuropore closure Source: RGD
- blood vessel development Source: RGD
- chromatin remodeling Source: RGD
- embryonic body morphogenesis Source: RGD
- histone deacetylation Source: RGD
- in utero embryonic development Source: RGD
- negative regulation of transcription, DNA-templated Source: RGD
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- neural fold formation Source: RGD
- programmed cell death Source: RGD
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Enzyme and pathway databases
Reactomei | R-RNO-3214815, HDACs deacetylate histones R-RNO-6804758, Regulation of TP53 Activity through Acetylation R-RNO-73762, RNA Polymerase I Transcription Initiation R-RNO-8943724, Regulation of PTEN gene transcription |
Names & Taxonomyi
Protein namesi | Submitted name: GATA zinc finger domain-containing 2A |
Gene namesi | Name:Gatad2aImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1310596, Gatad2a |
Subcellular locationi
Nucleus
- nucleus Source: RGD
- NuRD complex Source: RGD
Keywords - Cellular componenti
NucleusARBA annotationPTM / Processingi
Proteomic databases
jPOSTi | G3V8R7 |
PaxDbi | G3V8R7 |
PTM databases
iPTMneti | G3V8R7 |
PhosphoSitePlusi | G3V8R7 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000022173, Expressed in brain and 21 other tissues |
Structurei
3D structure databases
AlphaFoldDBi | G3V8R7 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Keywords - Domaini
Coiled coilARBA annotationPhylogenomic databases
eggNOGi | KOG3740, Eukaryota |
GeneTreei | ENSGT00390000004097 |
HOGENOMi | CLU_014315_1_0_1 |
InParanoidi | G3V8R7 |
OMAi | GAAWKKN |
TreeFami | TF321369 |
Family and domain databases
InterProi | View protein in InterPro IPR040386, P66 IPR032346, P66_CC |
PANTHERi | PTHR13455, PTHR13455, 1 hit |
Pfami | View protein in Pfam PF16563, P66_CC, 1 hit |
i Sequence
Sequence statusi: Complete.
G3V8R7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEEACRTRS QKRAFEPDLT EDDVESKKMK MERGPSELPV DGDSRVMPEP
60 70 80 90 100
SAGPAQGLLR TTEAMGTGSG EGLLGDGPVD MRTSHSDMKS EKRPPSPDVI
110 120 130 140 150
VLSDSEQPSS PRVNGLTTVA LKDTSTEALL KSSPEERERM IKQLKEELRL
160 170 180 190 200
EEAKLVLLKK LRQSQIQKEA TAQKPTASSG STVTTPPPLV RGPQNIPAGK
210 220 230 240 250
PSLQTSSTRI PGSIIPPPLV RGGQQVSAKL GPQASSQVVM PPLVRGAQVS
260 270 280 290 300
QIHNIRQHSS TGPPPLLLAP RASVPSMQIQ GQRIIQQGLI RVANVPNTSL
310 320 330 340 350
LVNIPQPTAA SLKGTTVGSA QANSTPSSVA SVVASAESPA SRQAAAKLAL
360 370 380 390 400
RKQLEKTLLE IPPPKPPAPE MNFLPSAANN EFIYLVGLEE VVQNLLETQA
410 420 430 440 450
GRISATSAAA VLSREPYMCV QCKTDFTCRW REKGGAVMCE NCMTSNQKKA
460 470 480 490 500
LKVEHTSRLK AAFVKALQQE QEMEQRLLQQ GVGTASIKAE TAAPHPSLKQ
510 520 530 540 550
VIKPRRKLAF RSGEARDWNN GSVLQTSSQL SRGSATTPRG VLHTFSQSPK
560 570 580 590 600
LQNAASATAL VSRTGRHSER VVGTSKGTAS NWKKTPLSTG GTLAFVSPSL
610 620 630
AVHKSSSAVD RQREYLLDMI PPRSIPQSAT WK
Genome annotation databases
Ensembli | ENSRNOT00000027943.7; ENSRNOP00000027943.6; ENSRNOG00000022173.6 |
Similar proteinsi
Cross-referencesi
3D structure databases
AlphaFoldDBi | G3V8R7 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000027943 |
PTM databases
iPTMneti | G3V8R7 |
PhosphoSitePlusi | G3V8R7 |
Proteomic databases
jPOSTi | G3V8R7 |
PaxDbi | G3V8R7 |
Genome annotation databases
Ensembli | ENSRNOT00000027943.7; ENSRNOP00000027943.6; ENSRNOG00000022173.6 |
Organism-specific databases
RGDi | 1310596, Gatad2a |
Phylogenomic databases
eggNOGi | KOG3740, Eukaryota |
GeneTreei | ENSGT00390000004097 |
HOGENOMi | CLU_014315_1_0_1 |
InParanoidi | G3V8R7 |
OMAi | GAAWKKN |
TreeFami | TF321369 |
Enzyme and pathway databases
Reactomei | R-RNO-3214815, HDACs deacetylate histones R-RNO-6804758, Regulation of TP53 Activity through Acetylation R-RNO-73762, RNA Polymerase I Transcription Initiation R-RNO-8943724, Regulation of PTEN gene transcription |
Gene expression databases
Bgeei | ENSRNOG00000022173, Expressed in brain and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR040386, P66 IPR032346, P66_CC |
PANTHERi | PTHR13455, PTHR13455, 1 hit |
Pfami | View protein in Pfam PF16563, P66_CC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V8R7_RAT | |
Accessioni | G3V8R7Primary (citable) accession number: G3V8R7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | May 25, 2022 | |
Last modified: | May 25, 2022 | |
This is version 60 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |