Mycl

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: InterPro
protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of inner ear auditory receptor cell differentiation Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingUniRule annotation

Molecular function

DNA-bindingUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MYCL proto-oncogene, bHLH transcription factorImported Submitted name: V-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (Avian) (Mapped)Imported
Gene namesⁱ	Name:MyclImported Synonyms:Mycl1Imported, Mycl1_mappedImported ORF Names:rCG_63007Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 5

Organism-specific databases

Rat genome database More...RGDⁱ	1588591 Mycl

RGDⁱ

1588591 Mycl

Keywords - Cellular componentⁱ

NucleusUniRule annotation

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	G3V7T4

PRIDEⁱ

G3V7T4

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Interactionⁱ

Subunit structureⁱ

Efficient DNA binding requires dimerization with another bHLH protein.UniRule annotation

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000019101

STRINGⁱ

10116.ENSRNOP00000019101

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	286 – 338	BHLHInterPro annotationAdd BLAST		53

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	235 – 255	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IFII Eukaryota ENOG410Y7JV LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00510000046414
KEGG Orthology (KO) More...KOⁱ	K09110
OMAⁱ	AWGRNYA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ZJQ
TreeFamⁱ	TF106001

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR002418 Tscrpt_reg_Myc IPR012682 Tscrpt_reg_Myc_N
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit PF01056 Myc_N, 2 hits
PIRSFⁱ	PIRSF001705 Myc_protein, 2 hits
PRINTSⁱ	PR00044 LEUZIPPRMYC
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

G3V7T4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDFDSYQHYF YDYDCGEDFY RSTAPSEDIW KKFELVPSPP TSPPWGSGPG 
        60         70         80         90        100
AVDPASGISP GEPWPGGGAG DEAESRGHSK AWGRNYASII RRDCMWSGFS 
       110        120        130        140        150
ARERLERVVS DRLAPGVPRG NPPKAPATPD GTPSLEASNP APATQCQLGE 
       160        170        180        190        200
PKTQACSGSE SPSDSEGEEI DVVTVEKRRS LDIRKPVTIT VRADPLDPCM 
       210        220        230        240        250
KHFHISIHQQ QHNYAARFPP ESCSQEGDPE PGAQEEALEI EAPKEKEEEE 
       260        270        280        290        300
EEEEEEEEIV SPPPVENEAP QSCHPKPVSS DTEDVTKRKN HNFLERKRRN 
       310        320        330        340        350
DLRSRFLALR DQVPTLASCS KAPKVVILSK ALEYLQALVG AEKKMATEKR 
       360 
QLRCRQQQLQ KRIAYLSGY

Length:369

Mass (Da):41,068

Last modified:November 16, 2011 - v1

Checksum:ⁱF508F5B8D3B3F4F3

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07049850 Genomic DNA No translation available. CH473968 Genomic DNA Translation: EDL80364.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001178692.1, NM_001191763.1 XP_006238857.1, XM_006238795.3 XP_008762224.1, XM_008764002.2
UniGeneⁱ	Rn.230775

Genome annotation databases

Ensemblⁱ	ENSRNOT00000019101; ENSRNOP00000019101; ENSRNOG00000014259
GeneIDⁱ	298506
KEGGⁱ	rno:298506

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
G3V7T4	Protein L-Myc		MOUSE		368	UniRef90_P10166
protein L-Myc		MESAU		398
UPI00042AF83D		PERMB		398
UPI000A3071F9		MUSPA		398
UPI000B4F2564		MERUN		398
+11

Protein	Similar proteins		Species	Score	Length	Source
G3V7T4	Protein L-Myc		HUMAN		364	UniRef50_P12524
Protein L-Myc		MOUSE		368
protein L-Myc isoform X1		ODORO		403
Uncharacterized protein		RABIT		396
MYCL proto-oncogene, bHLH transcription factor		CALJA		395
+71

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07049850 Genomic DNA No translation available. CH473968 Genomic DNA Translation: EDL80364.1
RefSeqⁱ	NP_001178692.1, NM_001191763.1 XP_006238857.1, XM_006238795.3 XP_008762224.1, XM_008764002.2
UniGeneⁱ	Rn.230775

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000019101

STRINGⁱ

10116.ENSRNOP00000019101

Proteomic databases

PRIDEⁱ	G3V7T4

PRIDEⁱ

G3V7T4

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000019101; ENSRNOP00000019101; ENSRNOG00000014259
GeneIDⁱ	298506
KEGGⁱ	rno:298506

Organism-specific databases

CTDⁱ	4610
RGDⁱ	1588591 Mycl

Phylogenomic databases

eggNOGⁱ	ENOG410IFII Eukaryota ENOG410Y7JV LUCA
GeneTreeⁱ	ENSGT00510000046414
KOⁱ	K09110
OMAⁱ	AWGRNYA
OrthoDBⁱ	EOG091G0ZJQ
TreeFamⁱ	TF106001

Gene expression databases

Bgeeⁱ	ENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR002418 Tscrpt_reg_Myc IPR012682 Tscrpt_reg_Myc_N
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit PF01056 Myc_N, 2 hits
PIRSFⁱ	PIRSF001705 Myc_protein, 2 hits
PRINTSⁱ	PR00044 LEUZIPPRMYC
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	G3V7T4_RAT
Accessionⁱ	G3V7T4Primary (citable) accession number: G3V7T4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 16, 2011
	Last sequence update:	November 16, 2011
	Last modified:	November 7, 2018
	This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - G3V7T4 (G3V7T4_RAT)

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MYCL proto-oncogene, bHLH transcription factor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ