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Protein
Submitted name:

MYCL proto-oncogene, bHLH transcription factor

Gene

Mycl

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MYCL proto-oncogene, bHLH transcription factorImported
Submitted name:
V-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (Avian) (Mapped)Imported
Gene namesi
Name:MyclImported
Synonyms:Mycl1Imported, Mycl1_mappedImported
ORF Names:rCG_63007Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1588591 Mycl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiG3V7T4

Expressioni

Gene expression databases

BgeeiENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Interactioni

Subunit structurei

Efficient DNA binding requires dimerization with another bHLH protein.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019101

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini286 – 338BHLHInterPro annotationAdd BLAST53

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili235 – 255Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IFII Eukaryota
ENOG410Y7JV LUCA
GeneTreeiENSGT00510000046414
KOiK09110
OMAiAWGRNYA
OrthoDBiEOG091G0ZJQ
TreeFamiTF106001

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF00010 HLH, 1 hit
PF01056 Myc_N, 2 hits
PIRSFiPIRSF001705 Myc_protein, 2 hits
PRINTSiPR00044 LEUZIPPRMYC
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

G3V7T4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFDSYQHYF YDYDCGEDFY RSTAPSEDIW KKFELVPSPP TSPPWGSGPG
60 70 80 90 100
AVDPASGISP GEPWPGGGAG DEAESRGHSK AWGRNYASII RRDCMWSGFS
110 120 130 140 150
ARERLERVVS DRLAPGVPRG NPPKAPATPD GTPSLEASNP APATQCQLGE
160 170 180 190 200
PKTQACSGSE SPSDSEGEEI DVVTVEKRRS LDIRKPVTIT VRADPLDPCM
210 220 230 240 250
KHFHISIHQQ QHNYAARFPP ESCSQEGDPE PGAQEEALEI EAPKEKEEEE
260 270 280 290 300
EEEEEEEEIV SPPPVENEAP QSCHPKPVSS DTEDVTKRKN HNFLERKRRN
310 320 330 340 350
DLRSRFLALR DQVPTLASCS KAPKVVILSK ALEYLQALVG AEKKMATEKR
360
QLRCRQQQLQ KRIAYLSGY
Length:369
Mass (Da):41,068
Last modified:November 16, 2011 - v1
Checksum:iF508F5B8D3B3F4F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07049850 Genomic DNA No translation available.
CH473968 Genomic DNA Translation: EDL80364.1
RefSeqiNP_001178692.1, NM_001191763.1
XP_006238857.1, XM_006238795.3
XP_008762224.1, XM_008764002.2
UniGeneiRn.230775

Genome annotation databases

EnsembliENSRNOT00000019101; ENSRNOP00000019101; ENSRNOG00000014259
GeneIDi298506
KEGGirno:298506

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07049850 Genomic DNA No translation available.
CH473968 Genomic DNA Translation: EDL80364.1
RefSeqiNP_001178692.1, NM_001191763.1
XP_006238857.1, XM_006238795.3
XP_008762224.1, XM_008764002.2
UniGeneiRn.230775

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019101

Proteomic databases

PRIDEiG3V7T4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019101; ENSRNOP00000019101; ENSRNOG00000014259
GeneIDi298506
KEGGirno:298506

Organism-specific databases

CTDi4610
RGDi1588591 Mycl

Phylogenomic databases

eggNOGiENOG410IFII Eukaryota
ENOG410Y7JV LUCA
GeneTreeiENSGT00510000046414
KOiK09110
OMAiAWGRNYA
OrthoDBiEOG091G0ZJQ
TreeFamiTF106001

Gene expression databases

BgeeiENSRNOG00000014259 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF00010 HLH, 1 hit
PF01056 Myc_N, 2 hits
PIRSFiPIRSF001705 Myc_protein, 2 hits
PRINTSiPR00044 LEUZIPPRMYC
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V7T4_RAT
AccessioniPrimary (citable) accession number: G3V7T4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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