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Entry version 72 (29 Sep 2021)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

Myomesin 2

Gene

Myom2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myomesin 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Myom2Imported
ORF Names:rCG_43076Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Rat genome database

More...
RGDi
631437, Myom2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
G3V7K1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000011754, Expressed in skeletal muscle tissue and 20 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000015908

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
G3V7K1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini154 – 245Ig-likeInterPro annotationAdd BLAST92
Domaini266 – 354Ig-likeInterPro annotationAdd BLAST89
Domaini385 – 480Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini513 – 608Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini614 – 707Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini710 – 812Fibronectin type-IIIInterPro annotationAdd BLAST103
Domaini815 – 912Fibronectin type-IIIInterPro annotationAdd BLAST98
Domaini1130 – 1212Ig-likeInterPro annotationAdd BLAST83
Domaini1359 – 1435Ig-likeInterPro annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni34 – 63DisorderedSequence analysisAdd BLAST30
Regioni1445 – 1464DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili101 – 128Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, Immunoglobulin domainARBA annotation, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QS6D, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157057

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004753_1_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
KKDQGEY

Database of Orthologous Groups

More...
OrthoDBi
57219at2759

TreeFam database of animal gene trees

More...
TreeFami
TF331825

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 5 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 12 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 5 hits
SM00409, IG, 4 hits
SM00408, IGc2, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 6 hits
SSF49265, SSF49265, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 5 hits
PS50835, IG_LIKE, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G3V7K1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLVVVPFYQ KRHKHFDQSY RNIQTRYLLD RYASKKQASS QSSSQRSLTE
60 70 80 90 100
RSSSKRASSQ SSAEGMTCRL CAKRMSASEE EEVENENRYR SLAASYGEAK
110 120 130 140 150
RQRFLSELAQ LEENVQLART QARNKLDKYF LEQTVADNLA LERSSFEDRL
160 170 180 190 200
SRAPEILVRL RSHTIWERMS VRLCFTVQGF PTPVVQWYKD GSLICQAGEP
210 220 230 240 250
GKYRIESRYG VHTLEINRAD FEDTATYSAV ATNPHGQVST NAAVVVRRYR
260 270 280 290 300
GDEEPYHSVG LPIGLPLSSV IPYTHFDVQF LEKFGVTFRR EGETVTLKCT
310 320 330 340 350
LLVTPDLKRV QPRAEWYRDD VLLKESKWTK MFFGEGQASL SFSHLNKDDE
360 370 380 390 400
GLYTLRIVSR GGVSDHSAFM FVRDADPLVT GAPGAPMDLQ CHDANRDYVI
410 420 430 440 450
VTWKPPNTTT ESPVIGYFID KCEVGTNNWV QCNDAPVKIC KYPVTGLFEG
460 470 480 490 500
RSYVFRVRAV NNAGISRPSR ISDAVAALDP VDLRRLQAIH LEGEKEIVIY
510 520 530 540 550
QDDLEGDVQI PGPPTNVQAS EVSRNYVVLS WDPPSPRGKE PLMYFIEKSA
560 570 580 590 600
VGSGSWQRVN AQTAVRSPRY AVFDLAEGKS YVFRVLSANK HGLSDPSEIT
610 620 630 640 650
PPIQAQDMIV VPSAPGRVLA SRNTKTSVVV QWDRPKHEED LLGYYVDCCV
660 670 680 690 700
AGTNMWEPCN HKPIGYNRFV VHGLTTGEQY IFRVKAVNAV GTSENSQESE
710 720 730 740 750
VIKVQAALTV PSHPYGITLL NCDGHSMTLG WKVPKFSGGS AIIGYYLDKR
760 770 780 790 800
EVHHKNWHEI NSSPVKERIL TVEGLTEGSL YEFKIAATNL AGIGQPSDPS
810 820 830 840 850
EHFKCEAWTA PEPGPAYDLT FCEVRDTSLV ILWKAPVYSG SSPVSGYFVD
860 870 880 890 900
FKEEDSGEWK TTSEAATPNR YLKVCDLHQG KTYVFRVRAV NASGPGKPSD
910 920 930 940 950
TSEPVLVEAR PGTKEISAGV DEEGNIYLGF DCQEMTDASQ FTWCKAYEEI
960 970 980 990 1000
ADEERFEVHT EGDHSKLYFK NPDKIDIGTY SVSVSDTDGV SSSFVLDEEE
1010 1020 1030 1040 1050
LERLMALSNE IKNPTIPLKS ELAYEIFDKG QVRFWLQAEH LSPDANFRFI
1060 1070 1080 1090 1100
INDREVSDSE THRIKCDRST GMIEMVMDRF TIENEGTYTV QIQDGKAKNQ
1110 1120 1130 1140 1150
SSLVLIGDAF RAVLEEAEFQ RKEFLRKQGP HFAEYLHWDV TEECEVRLIC
1160 1170 1180 1190 1200
KVANTKRETV FKWLKDDVLY ETETPPPDLE KGICELLIPK LSKKDHGEYK
1210 1220 1230 1240 1250
ATLKDDRGQD VSVLEVAGKV YEDMILAMSR VCGASASPLK VLCTPEGIRL
1260 1270 1280 1290 1300
QCFMKYFTEE MKVSWYHKEA KISSSEHMRI GGSEEMAWLQ ICEPTEKDKG
1310 1320 1330 1340 1350
KYTFEIFDGK DNHQRSLDLS GQAFDEAYAE FQQLKAAAFA EKNRGKVIGG
1360 1370 1380 1390 1400
LPDVVTIMEG KTLNLTCTVF GNPDPEVVWF KNDKDIELSE HFSVKVEQSK
1410 1420 1430 1440 1450
YVSLTIKGVT AEDSGKYSIN VKNKYGGEKI DVTVSVYKHG EKIPDISAPQ
1460
QAKPKLIPAS TSAD
Length:1,464
Mass (Da):164,713
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA51BD2EDC373CC40
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07026503 Genomic DNA No translation available.
AABR07026504 Genomic DNA No translation available.
AABR07026505 Genomic DNA No translation available.
AABR07026506 Genomic DNA No translation available.
CH473970 Genomic DNA Translation: EDM08942.1

NCBI Reference Sequences

More...
RefSeqi
NP_001162612.1, NM_001169141.1
XP_006253451.1, XM_006253389.3
XP_008769582.1, XM_008771360.2
XP_017455650.1, XM_017600161.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000015908; ENSRNOP00000015908; ENSRNOG00000011754

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
306616

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:306616

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07026503 Genomic DNA No translation available.
AABR07026504 Genomic DNA No translation available.
AABR07026505 Genomic DNA No translation available.
AABR07026506 Genomic DNA No translation available.
CH473970 Genomic DNA Translation: EDM08942.1
RefSeqiNP_001162612.1, NM_001169141.1
XP_006253451.1, XM_006253389.3
XP_008769582.1, XM_008771360.2
XP_017455650.1, XM_017600161.1

3D structure databases

SMRiG3V7K1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015908

PTM databases

PhosphoSitePlusiG3V7K1

Genome annotation databases

EnsembliENSRNOT00000015908; ENSRNOP00000015908; ENSRNOG00000011754
GeneIDi306616
KEGGirno:306616

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9172
RGDi631437, Myom2

Phylogenomic databases

eggNOGiENOG502QS6D, Eukaryota
GeneTreeiENSGT00940000157057
HOGENOMiCLU_004753_1_0_1
OMAiKKDQGEY
OrthoDBi57219at2759
TreeFamiTF331825

Gene expression databases

BgeeiENSRNOG00000011754, Expressed in skeletal muscle tissue and 20 other tissues

Family and domain databases

CDDicd00063, FN3, 5 hits
Gene3Di2.60.40.10, 12 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
PfamiView protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 3 hits
SMARTiView protein in SMART
SM00060, FN3, 5 hits
SM00409, IG, 4 hits
SM00408, IGc2, 3 hits
SUPFAMiSSF48726, SSF48726, 6 hits
SSF49265, SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 5 hits
PS50835, IG_LIKE, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3V7K1_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3V7K1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 29, 2021
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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