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Protein
Submitted name:

Serine/arginine-rich-splicing factor 5

Gene

SRSF5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/arginine-rich-splicing factor 5Imported
Gene namesi
Name:SRSF5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000100650.15
HGNCiHGNC:10787 SRSF5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100650

PTM / Processingi

Proteomic databases

MaxQBiG3V5K8
PeptideAtlasiG3V5K8
PRIDEiG3V5K8

Expressioni

Gene expression databases

BgeeiENSG00000100650 Expressed in 238 organ(s), highest expression level in left lobe of thyroid gland
ExpressionAtlasiG3V5K8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliG3V5K8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 74RRMInterPro annotationAdd BLAST71

Phylogenomic databases

eggNOGiKOG0106 Eukaryota
COG0724 LUCA
GeneTreeiENSGT00910000144049

Family and domain databases

CDDicd12337 RRM1_SRSF4_like, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR035585 RRM1_SRSF4-like
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

G3V5K8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGCRVFIGR LNPAAREKDV ERFFKGYGRI RDIDLKRGFG FVEFEDPRDA
60 70 80 90
DDAVYELDGK ELCSERVTIE HARARSRGGR GRGRYSDRFS SRRPRNDRR
Length:99
Mass (Da):11,587
Last modified:November 16, 2011 - v1
Checksum:iC6649A9E684F7426
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q13243SRSF5_HUMAN
Serine/arginine-rich splicing facto...
SRSF5 HRS, SFRS5, SRP40
272Annotation score:
B4DUA4B4DUA4_HUMAN
Serine/arginine-rich-splicing facto...
SRSF5
138Annotation score:
B4DJK0B4DJK0_HUMAN
Serine/arginine-rich-splicing facto...
SRSF5
124Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157789 Genomic DNA No translation available.
AL355837 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000553548; ENSP00000452400; ENSG00000100650
UCSCiuc059cvk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157789 Genomic DNA No translation available.
AL355837 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliG3V5K8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiG3V5K8
PeptideAtlasiG3V5K8
PRIDEiG3V5K8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000553548; ENSP00000452400; ENSG00000100650
UCSCiuc059cvk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000100650.15
HGNCiHGNC:10787 SRSF5
OpenTargetsiENSG00000100650
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0106 Eukaryota
COG0724 LUCA
GeneTreeiENSGT00910000144049

Miscellaneous databases

ChiTaRSiSRSF5 human

Gene expression databases

BgeeiENSG00000100650 Expressed in 238 organ(s), highest expression level in left lobe of thyroid gland
ExpressionAtlasiG3V5K8 baseline and differential

Family and domain databases

CDDicd12337 RRM1_SRSF4_like, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR035585 RRM1_SRSF4-like
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V5K8_HUMAN
AccessioniPrimary (citable) accession number: G3V5K8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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