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UniProtKB - G3V5E1 (G3V5E1_HUMAN)
Protein
Submitted name:
Cyclin-K
Gene
CCNK
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: InterPro
Keywordsi
Molecular function | CyclinUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Cyclin-K |
Gene namesi | Name:CCNK |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1596, CCNK |
VEuPathDBi | HostDB:ENSG00000090061 |
PTM / Processingi
Proteomic databases
EPDi | G3V5E1 |
MaxQBi | G3V5E1 |
PeptideAtlasi | G3V5E1 |
PRIDEi | G3V5E1 |
ProteomicsDBi | 33500 |
Expressioni
Gene expression databases
Bgeei | ENSG00000090061, Expressed in testis and 219 other tissues |
ExpressionAtlasi | G3V5E1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 55 – 149 | CYCLINInterPro annotationAdd BLAST | 95 | |
Domaini | 158 – 278 | Cyclin_CInterPro annotationAdd BLAST | 121 | |
Domaini | 162 – 256 | CYCLINInterPro annotationAdd BLAST | 95 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 262 – 378 | DisorderedSequence analysisAdd BLAST | 117 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 284 – 319 | Polar residuesSequence analysisAdd BLAST | 36 | |
Compositional biasi | 351 – 378 | Pro residuesSequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the cyclin family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000156384 |
HOGENOMi | CLU_022000_0_0_1 |
Family and domain databases
CDDi | cd00043, CYCLIN, 2 hits |
InterProi | View protein in InterPro IPR013763, Cyclin-like IPR036915, Cyclin-like_sf IPR043198, Cyclin/Ssn8 IPR004367, Cyclin_C-dom IPR006671, Cyclin_N |
PANTHERi | PTHR10026, PTHR10026, 1 hit |
Pfami | View protein in Pfam PF02984, Cyclin_C, 1 hit PF00134, Cyclin_N, 1 hit |
SMARTi | View protein in SMART SM00385, CYCLIN, 2 hits SM01332, Cyclin_C, 1 hit |
SUPFAMi | SSF47954, SSF47954, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
G3V5E1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR
60 70 80 90 100
REGARFIFDV GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL
110 120 130 140 150
FLAGKVEETP KKCKDIIKTA RSLLNDVQFG QFGDDPKEEV MVLERILLQT
160 170 180 190 200
IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK LVQMAWTFVN DSLCTTLSLQ
210 220 230 240 250
WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ DVPVDVLEDI
260 270 280 290 300
CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQVQQ SQPSQSSEPS
310 320 330 340 350
QPQQKDPQQP AQQQQPAQQP KKPSPQPSSP RQVKRAVVVS PKEENKAAEP
360 370
PPPKIPKIET THPPLPPAHP PPASTHPP
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO75909 | CCNK_HUMAN | Cyclin-K | CCNK CPR4 | 580 | Annotation score: | ||
G3V2Q3 | G3V2Q3_HUMAN | Cyclin-K | CCNK | 227 | Annotation score: | ||
G3V235 | G3V235_HUMAN | Cyclin-K | CCNK | 109 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL110504 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000555049.5; ENSP00000452307.1; ENSG00000090061.17 |
UCSCi | uc059ezs.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL110504 Genomic DNA No translation available. |
3D structure databases
SMRi | G3V5E1 |
ModBasei | Search... |
Proteomic databases
EPDi | G3V5E1 |
MaxQBi | G3V5E1 |
PeptideAtlasi | G3V5E1 |
PRIDEi | G3V5E1 |
ProteomicsDBi | 33500 |
Protocols and materials databases
Antibodypediai | 102, 182 antibodies from 23 providers |
Genome annotation databases
Ensembli | ENST00000555049.5; ENSP00000452307.1; ENSG00000090061.17 |
UCSCi | uc059ezs.1, human |
Organism-specific databases
HGNCi | HGNC:1596, CCNK |
OpenTargetsi | ENSG00000090061 |
VEuPathDBi | HostDB:ENSG00000090061 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156384 |
HOGENOMi | CLU_022000_0_0_1 |
Miscellaneous databases
ChiTaRSi | CCNK, human |
Gene expression databases
Bgeei | ENSG00000090061, Expressed in testis and 219 other tissues |
ExpressionAtlasi | G3V5E1, baseline and differential |
Family and domain databases
CDDi | cd00043, CYCLIN, 2 hits |
InterProi | View protein in InterPro IPR013763, Cyclin-like IPR036915, Cyclin-like_sf IPR043198, Cyclin/Ssn8 IPR004367, Cyclin_C-dom IPR006671, Cyclin_N |
PANTHERi | PTHR10026, PTHR10026, 1 hit |
Pfami | View protein in Pfam PF02984, Cyclin_C, 1 hit PF00134, Cyclin_N, 1 hit |
SMARTi | View protein in SMART SM00385, CYCLIN, 2 hits SM01332, Cyclin_C, 1 hit |
SUPFAMi | SSF47954, SSF47954, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V5E1_HUMAN | |
Accessioni | G3V5E1Primary (citable) accession number: G3V5E1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | May 25, 2022 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |