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Protein
Submitted name:

FERM domain-containing protein 6

Gene

FRMD6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
FERM domain-containing protein 6Imported
Gene namesi
Name:FRMD6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000139926.15
HGNCiHGNC:19839 FRMD6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000139926

PTM / Processingi

Proteomic databases

PeptideAtlasiG3V517
PRIDEiG3V517

Expressioni

Gene expression databases

BgeeiENSG00000139926 Expressed in 204 organ(s), highest expression level in tibia
ExpressionAtlasiG3V517 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliG3V517
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 61FERMInterPro annotationAdd BLAST46

Phylogenomic databases

eggNOGiENOG410IUGZ Eukaryota
ENOG410Z6XT LUCA
GeneTreeiENSGT00930000150997

Family and domain databases

InterProiView protein in InterPro
IPR000299 FERM_domain
IPR018979 FERM_N
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF09379 FERM_N, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

G3V517-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKLNFHNNR VMQDRRSVCI FLPNDESLNI IINVKILCHQ LLVQVCDLLR
60
LKDCHLFGLS V
Length:61
Mass (Da):7,149
Last modified:November 16, 2011 - v1
Checksum:i6F7ACC5B4640D1C7
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96NE9FRMD6_HUMAN
FERM domain-containing protein 6
FRMD6 C14orf31
622Annotation score:
G3V4T7G3V4T7_HUMAN
FERM domain-containing protein 6
FRMD6
545Annotation score:
H0YJ19H0YJ19_HUMAN
FERM domain-containing protein 6
FRMD6
129Annotation score:
G3V3V8G3V3V8_HUMAN
FERM domain-containing protein 6
FRMD6
120Annotation score:
H0YJC1H0YJC1_HUMAN
FERM domain-containing protein 6
FRMD6
205Annotation score:
G3V2L4G3V2L4_HUMAN
FERM domain-containing protein 6
FRMD6
143Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei61Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079307 Genomic DNA No translation available.
AL122125 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000554778; ENSP00000452122; ENSG00000139926
UCSCiuc059bmc.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079307 Genomic DNA No translation available.
AL122125 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliG3V517
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiG3V517
PRIDEiG3V517

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000554778; ENSP00000452122; ENSG00000139926
UCSCiuc059bmc.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000139926.15
HGNCiHGNC:19839 FRMD6
OpenTargetsiENSG00000139926
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IUGZ Eukaryota
ENOG410Z6XT LUCA
GeneTreeiENSGT00930000150997

Miscellaneous databases

ChiTaRSiFRMD6 human

Gene expression databases

BgeeiENSG00000139926 Expressed in 204 organ(s), highest expression level in tibia
ExpressionAtlasiG3V517 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000299 FERM_domain
IPR018979 FERM_N
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF09379 FERM_N, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V517_HUMAN
AccessioniPrimary (citable) accession number: G3V517
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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