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Protein
Submitted name:

ERO1-like protein alpha

Gene

ERO1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
ERO1-like protein alphaImported
Gene namesi
Name:ERO1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000197930.12
HGNCiHGNC:13280 ERO1A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197930

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500345732424 – 125Sequence analysisAdd BLAST102

Proteomic databases

MaxQBiG3V503
PeptideAtlasiG3V503
PRIDEiG3V503

Expressioni

Gene expression databases

BgeeiENSG00000197930 Expressed in 218 organ(s), highest expression level in esophagus squamous epithelium
ExpressionAtlasiG3V503 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliG3V503
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2608 Eukaryota
COG5061 LUCA
GeneTreeiENSGT00390000007753

Family and domain databases

InterProiView protein in InterPro
IPR007266 Ero1
IPR037192 ERO1-like_sf
PANTHERiPTHR12613 PTHR12613, 1 hit
PfamiView protein in Pfam
PF04137 ERO1, 1 hit
SUPFAMiSSF110019 SSF110019, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

G3V503-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRGWGFLFG LLGAVWLLSS GHGEEQPPET AAQRCFCQVS GYLDDCTCDV
60 70 80 90 100
ETIDRFNNYR LFPRLQKLLE SDYFRYYKVN LKRPCPFWND ISQCGRRDCA
110 120
VKPCQSDEVP DGIKSASYKV CTYTY
Length:125
Mass (Da):14,405
Last modified:November 16, 2011 - v1
Checksum:i7E05EA40D2587412
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96HE7ERO1A_HUMAN
ERO1-like protein alpha
ERO1A ERO1L, UNQ434/PRO865
468Annotation score:
G3V5B3G3V5B3_HUMAN
ERO1-like protein alpha
ERO1A
169Annotation score:
G3V3E6G3V3E6_HUMAN
ERO1-like protein alpha
ERO1A
257Annotation score:
G3V2H0G3V2H0_HUMAN
ERO1-like protein alpha
ERO1A
75Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133453 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000556223; ENSP00000452093; ENSG00000197930
UCSCiuc059boj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133453 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliG3V503
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiG3V503
PeptideAtlasiG3V503
PRIDEiG3V503

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000556223; ENSP00000452093; ENSG00000197930
UCSCiuc059boj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000197930.12
HGNCiHGNC:13280 ERO1A
OpenTargetsiENSG00000197930
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2608 Eukaryota
COG5061 LUCA
GeneTreeiENSGT00390000007753

Miscellaneous databases

ChiTaRSiERO1A human

Gene expression databases

BgeeiENSG00000197930 Expressed in 218 organ(s), highest expression level in esophagus squamous epithelium
ExpressionAtlasiG3V503 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007266 Ero1
IPR037192 ERO1-like_sf
PANTHERiPTHR12613 PTHR12613, 1 hit
PfamiView protein in Pfam
PF04137 ERO1, 1 hit
SUPFAMiSSF110019 SSF110019, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V503_HUMAN
AccessioniPrimary (citable) accession number: G3V503
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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