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Protein
Submitted name:

Corticosteroid-binding globulin

Gene

SERPINA6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Corticosteroid-binding globulinImported
Gene namesi
Name:SERPINA6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000170099.5
HGNCiHGNC:1540 SERPINA6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170099

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501509165923 – 136Sequence analysisAdd BLAST114

Expressioni

Gene expression databases

BgeeiENSG00000170099 Expressed in 57 organ(s), highest expression level in right lobe of liver

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 134SERPINInterPro annotationAdd BLAST93

Sequence similaritiesi

Belongs to the serpin family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G3V4V7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLLLYTCLL WLPTSGLWTV QAMDPNAAYV NMSNHHRGLA SANVDFAFSL
60 70 80 90 100
YKHLVALSPK KNIFISPVSI SMALAMLSLG TCGHTRAQLL QGLGFNLTER
110 120 130
SETEIHQGFQ HLHQLFAKSD TSLEMTMGNA LFLDGS
Length:136
Mass (Da):14,965
Last modified:November 16, 2011 - v1
Checksum:i472867DED8047600
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P08185CBG_HUMAN
Corticosteroid-binding globulin
SERPINA6 CBG
405Annotation score:
G3V350G3V350_HUMAN
Corticosteroid-binding globulin
SERPINA6 hCG_22332
278Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei136Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117259 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000557225; ENSP00000452018; ENSG00000170099
ENST00000630843; ENSP00000486954; ENSG00000277405
UCSCiuc059esh.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117259 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000557225; ENSP00000452018; ENSG00000170099
ENST00000630843; ENSP00000486954; ENSG00000277405
UCSCiuc059esh.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000170099.5
HGNCiHGNC:1540 SERPINA6
OpenTargetsiENSG00000170099
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839

Miscellaneous databases

ChiTaRSiSERPINA6 human

Gene expression databases

BgeeiENSG00000170099 Expressed in 57 organ(s), highest expression level in right lobe of liver

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V4V7_HUMAN
AccessioniPrimary (citable) accession number: G3V4V7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 10, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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