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Protein
Submitted name:

Alpha-1-antitrypsin

Gene

SERPINA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-1-antitrypsinImported
Gene namesi
Name:SERPINA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000197249.12
HGNCiHGNC:8941 SERPINA1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197249

Expressioni

Gene expression databases

BgeeiENSG00000197249 Expressed in 207 organ(s), highest expression level in liver

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

G3V4I7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20 
MPSSVSWGIL LLAGLCCLVP VS
Length:22
Mass (Da):2,246
Last modified:November 16, 2011 - v1
Checksum:i9C50C51F188D755F
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P01009A1AT_HUMAN
Alpha-1-antitrypsin
SERPINA1 AAT, PI, PRO0684, PRO2209
418Annotation score:
A0A0B4J278A0A0B4J278_HUMAN
Alpha-1-antitrypsin
SERPINA1
144Annotation score:
A0A024R6I7A0A024R6I7_HUMAN
Alpha-1-antitrypsin
SERPINA1 hCG_2029168
418Annotation score:
G3V387G3V387_HUMAN
Alpha-1-antitrypsin
SERPINA1
117Annotation score:
G3V5R8G3V5R8_HUMAN
Alpha-1-antitrypsin
SERPINA1
92Annotation score:
G3V544G3V544_HUMAN
Alpha-1-antitrypsin
SERPINA1
156Annotation score:
A0A0G2JRN3A0A0G2JRN3_HUMAN
Alpha-1-antitrypsin
SERPINA1
359Annotation score:
G3V2B9G3V2B9_HUMAN
Alpha-1-antitrypsin
SERPINA1
105Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei22Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC235087 Genomic DNA No translation available.
AL132708 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000557118; ENSP00000451826; ENSG00000197249
ENST00000625866; ENSP00000487293; ENSG00000277377
UCSCiuc059esp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC235087 Genomic DNA No translation available.
AL132708 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000557118; ENSP00000451826; ENSG00000197249
ENST00000625866; ENSP00000487293; ENSG00000277377
UCSCiuc059esp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000197249.12
HGNCiHGNC:8941 SERPINA1
OpenTargetsiENSG00000197249
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839

Miscellaneous databases

ChiTaRSiSERPINA1 human

Gene expression databases

BgeeiENSG00000197249 Expressed in 207 organ(s), highest expression level in liver

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiG3V4I7_HUMAN
AccessioniPrimary (citable) accession number: G3V4I7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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