UniProtKB - G3V3A0 (G3V3A0_HUMAN)
Protein
Submitted name:
Alpha-1-antichymotrypsin
Gene
SERPINA3
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Alpha-1-antichymotrypsinImportedSubmitted name: Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 3, isoform CRA_aImported |
Gene namesi | Name:SERPINA3Imported ORF Names:hCG_2039549Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000196136.16 |
HGNCi | HGNC:16, SERPINA3 |
Subcellular locationi
Extracellular region or secreted
- extracellular space Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000196136, Expressed in liver and 111 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 202 | SERPINInterPro annotationAdd BLAST | 202 |
Sequence similaritiesi
Belongs to the serpin family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000154392 |
HOGENOMi | CLU_023330_6_0_1 |
Family and domain databases
Gene3Di | 2.30.39.10, 1 hit 3.30.497.10, 1 hit |
InterProi | View protein in InterPro IPR023795, Serpin_CS IPR023796, Serpin_dom IPR000215, Serpin_fam IPR036186, Serpin_sf IPR042178, Serpin_sf_1 IPR042185, Serpin_sf_2 |
PANTHERi | PTHR11461, PTHR11461, 1 hit |
Pfami | View protein in Pfam PF00079, Serpin, 1 hit |
SMARTi | View protein in SMART SM00093, SERPIN, 1 hit |
SUPFAMi | SSF56574, SSF56574, 1 hit |
PROSITEi | View protein in PROSITE PS00284, SERPIN, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
G3V3A0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPFDPQDTHQ SRFYLSKKKW VMVPMMSLHH LTIPYFRDEE LSCTVVELKY
60 70 80 90 100
TGNASALFIL PDQDKMEEVE AMLLPETLKR WRDSLEFREI GELYLPKFSI
110 120 130 140 150
SRDYNLNDIL LQLGIEEAFT SKADLSGITG ARNLAVSQVV HKAVLDVFEE
160 170 180 190 200
GTEASAATAV KITLLSALVE TRTIVRFNRP FLMIIVPTDT QNIFFMSKVT
NPKQA
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP01011 | AACT_HUMAN | Alpha-1-antichymotrypsin | SERPINA3 AACT, GIG24, GIG25 | 423 | Annotation score: | ||
G3V595 | G3V595_HUMAN | Alpha-1-antichymotrypsin | SERPINA3 | 305 | Annotation score: | ||
A0A087WY93 | A0A087WY93_HUMAN | Alpha-1-antichymotrypsin | SERPINA3 | 46 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049839 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW81587.1 |
Genome annotation databases
Ensembli | ENST00000482740; ENSP00000451119; ENSG00000196136 |
UCSCi | uc059eto.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049839 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW81587.1 |
3D structure databases
SMRi | G3V3A0 |
ModBasei | Search... |
Proteomic databases
MaxQBi | G3V3A0 |
PRIDEi | G3V3A0 |
ProteomicsDBi | 32878 |
Protocols and materials databases
Antibodypediai | 765, 546 antibodies |
Genome annotation databases
Ensembli | ENST00000482740; ENSP00000451119; ENSG00000196136 |
UCSCi | uc059eto.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000196136.16 |
HGNCi | HGNC:16, SERPINA3 |
OpenTargetsi | ENSG00000196136 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154392 |
HOGENOMi | CLU_023330_6_0_1 |
Miscellaneous databases
ChiTaRSi | SERPINA3, human |
Gene expression databases
Bgeei | ENSG00000196136, Expressed in liver and 111 other tissues |
Family and domain databases
Gene3Di | 2.30.39.10, 1 hit 3.30.497.10, 1 hit |
InterProi | View protein in InterPro IPR023795, Serpin_CS IPR023796, Serpin_dom IPR000215, Serpin_fam IPR036186, Serpin_sf IPR042178, Serpin_sf_1 IPR042185, Serpin_sf_2 |
PANTHERi | PTHR11461, PTHR11461, 1 hit |
Pfami | View protein in Pfam PF00079, Serpin, 1 hit |
SMARTi | View protein in SMART SM00093, SERPIN, 1 hit |
SUPFAMi | SSF56574, SSF56574, 1 hit |
PROSITEi | View protein in PROSITE PS00284, SERPIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V3A0_HUMAN | |
Accessioni | G3V3A0Primary (citable) accession number: G3V3A0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | October 7, 2020 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |