UniProtKB - G3V380 (G3V380_HUMAN)
Protein
Submitted name:
Alpha-actinin-1
Gene
ACTN1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Alpha-actinin-1Imported |
Gene namesi | Name:ACTN1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:163, ACTN1 |
VEuPathDBi | HostDB:ENSG00000072110.13 |
PTM / Processingi
Proteomic databases
MaxQBi | G3V380 |
PeptideAtlasi | G3V380 |
PRIDEi | G3V380 |
ProteomicsDBi | 32860 |
Expressioni
Gene expression databases
Bgeei | ENSG00000072110, Expressed in blood vessel layer and 247 other tissues |
ExpressionAtlasi | G3V380, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 30 – 72 | Calponin-homology (CH)InterPro annotationAdd BLAST | 43 |
Phylogenomic databases
GeneTreei | ENSGT00940000155548 |
HOGENOMi | CLU_2728791_0_0_1 |
Family and domain databases
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR001715, CH-domain IPR036872, CH_dom_sf |
Pfami | View protein in Pfam PF00307, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS50021, CH, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
G3V380-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGPGHSGQWQ EEVRNHSWWW GEGASTLPLL PACATFTAWC NSHLRKAGTQ
60 70
IENIEEDFRD GLKLMLLLEV IS
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP12814 | ACTN1_HUMAN | Alpha-actinin-1 | ACTN1 | 892 | Annotation score: | ||
H9KV75 | H9KV75_HUMAN | Alpha-actinin-1 | ACTN1 | 822 | Annotation score: | ||
H7C5W8 | H7C5W8_HUMAN | Alpha-actinin-1 | ACTN1 | 297 | Annotation score: | ||
H0YJW3 | H0YJW3_HUMAN | Alpha-actinin-1 | ACTN1 | 251 | Annotation score: | ||
G3V2W4 | G3V2W4_HUMAN | Alpha-actinin-1 | ACTN1 | 238 | Annotation score: | ||
H0YJ11 | H0YJ11_HUMAN | Alpha-actinin-1 | ACTN1 | 207 | Annotation score: | ||
G3V2N5 | G3V2N5_HUMAN | Alpha-actinin-1 | ACTN1 | 260 | Annotation score: | ||
G3V2X9 | G3V2X9_HUMAN | Alpha-actinin-1 | ACTN1 | 144 | Annotation score: | ||
G3V5M4 | G3V5M4_HUMAN | Alpha-actinin-1 | ACTN1 | 126 | Annotation score: | ||
G3V2E8 | G3V2E8_HUMAN | Alpha-actinin-1 | ACTN1 | 85 | Annotation score: | ||
There is more potential isoformShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 72 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL117694 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000553659; ENSP00000451086; ENSG00000072110 |
UCSCi | uc059ctr.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL117694 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | G3V380 |
PeptideAtlasi | G3V380 |
PRIDEi | G3V380 |
ProteomicsDBi | 32860 |
Protocols and materials databases
Antibodypediai | 51, 475 antibodies |
Genome annotation databases
Ensembli | ENST00000553659; ENSP00000451086; ENSG00000072110 |
UCSCi | uc059ctr.1, human |
Organism-specific databases
HGNCi | HGNC:163, ACTN1 |
OpenTargetsi | ENSG00000072110 |
VEuPathDBi | HostDB:ENSG00000072110.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155548 |
HOGENOMi | CLU_2728791_0_0_1 |
Miscellaneous databases
ChiTaRSi | ACTN1, human |
Gene expression databases
Bgeei | ENSG00000072110, Expressed in blood vessel layer and 247 other tissues |
ExpressionAtlasi | G3V380, baseline and differential |
Family and domain databases
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR001715, CH-domain IPR036872, CH_dom_sf |
Pfami | View protein in Pfam PF00307, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS50021, CH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V380_HUMAN | |
Accessioni | G3V380Primary (citable) accession number: G3V380 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | April 7, 2021 | |
This is version 55 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |