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UniProtKB - G3V2U4 (G3V2U4_HUMAN)

Entry version 65 (07 Apr 2021)
Sequence version 1 (16 Nov 2011)
Previous versions | rss
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Protein
Submitted name:

Protein unc-79 homolog

Gene

UNC79

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protein unc-79 homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UNC79Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:19966, UNC79

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000133958.13

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000133958

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		G3V2U4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		32741

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000133958, Expressed in right hemisphere of cerebellum and 99 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		G3V2U4, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni907 – 929DisorderedSequence analysisAdd BLAST23
Regioni1538 – 1575DisorderedSequence analysisAdd BLAST38
Regioni1607 – 1678DisorderedSequence analysisAdd BLAST72
Regioni1693 – 1832DisorderedSequence analysisAdd BLAST140
Regioni1863 – 1916DisorderedSequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1544 – 1559PolarSequence analysisAdd BLAST16
Compositional biasi1610 – 1632PolarSequence analysisAdd BLAST23
Compositional biasi1656 – 1678PolarSequence analysisAdd BLAST23
Compositional biasi1698 – 1713PolarSequence analysisAdd BLAST16
Compositional biasi1794 – 1832PolyampholyteSequence analysisAdd BLAST39
Compositional biasi1878 – 1916PolarSequence analysisAdd BLAST39

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011802

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000485_0_0_1

Identification of Orthologs from Complete Genome Data

More...OMAi		KKFSYQQ

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR024855, UNC79

The PANTHER Classification System

More...PANTHERi		PTHR21696, PTHR21696, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

G3V2U4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTKAEQFAS KIRYLQEYHN RVLHNIYPVP SGTDIANTLK YFSQTLLSIL 
        60         70         80         90        100
SRTGKKENQD ASNLTVPMTM CLFPVPFPLT PSLRPQVSSI NPTVTRSLLY 
       110        120        130        140        150
SVLRDAPSER GPQSRDAQLS DYPSLDYQGL YVTLVTLLDL VPLLQHGQHD 
       160        170        180        190        200
LGQSIFYTTT CLLPFLNDDI LSTLPYTMIS TLATFPPFLH KDIIEYLSTS 
       210        220        230        240        250
FLPMAILGSS RREGVPAHVN LSASSMLMIA MQYTSNPVYH CQLLECLMKY 
       260        270        280        290        300
KQEVWKDLLY VIAYGPSQVK PPAVQMLFHY WPNLKPPGAI SEYRGLQYTA 
       310        320        330        340        350
WNPIHCQHIE CHNAINKPAV KMCIDPSLSV ALGDKPPPLY LCEECSERIA 
       360        370        380        390        400
GDHSEWLIDV LLPQAEISAI CQKKNCSSHV RRAVVTCFSA GCCGRHGNRP 
       410        420        430        440        450
VRYCKRCHSN HHSNEVGAAA ETHLYQTSPP PINTRECGAE ELVCAVEAVI 
       460        470        480        490        500
SLLKEAEFHA EQREHELNRR RQLGLSSSHH SLDNADFDNK DDDKHDQRLL 
       510        520        530        540        550
SQFGIWFLVS LCTPSENTPT ESLARLVAMV FQWFHSTAYM MDDEVGSLVE 
       560        570        580        590        600
KLKPQFVTKW LKTVCDVRFD VMVMCLLPKP MEFARVGGYW DKSCSTVTQL 
       610        620        630        640        650
KEGLNRILCL IPYNVINQSV WECIMPEWLE AIRTEVPDNQ LKEFREVLSK 
       660        670        680        690        700
MFDIELCPLP FSMEEMFGFI SCRFTGYPSS VQEQALLWLH VLSELDIMVP 
       710        720        730        740        750
LQLLISMFSD GVNSVKELAN QRKSRVSELA GNLASRRVSV ASDPGRRVQH 
       760        770        780        790        800
NMLSPFHSPF QSPFRSPLRS PFRSPFKNFG HPGGRTIDFD CEDDEMNLNC 
       810        820        830        840        850
FILMFDLLLK QMELQDDGIT MGLEHSLSKD IISIINNVFQ APWGGSHTCQ 
       860        870        880        890        900
KDEKAIECNL CQSSILCYQL ACELLERLAP KEESRLVEPT DSLEDSLLSS 
       910        920        930        940        950
RPEFIIGPEG EEEENPASKH GENPGNCTEP VEHAAVKNDT ERKFCYQQLP 
       960        970        980        990       1000
VTLRLIYTIF QEMAKFEEPD ILFNMLNCLK ILCLHGECLY IARKDHPQFL 
      1010       1020       1030       1040       1050
AYIQDHMLIA SLWRVVKSEF SQLSSLAVPL LLHALSLPHG ADIFWTIING 
      1060       1070       1080       1090       1100
NFNSKDWKMR FEAVEKVAVI CRFLDIHSVT KNHLLKYSLA HAFCCFLTAV 
      1110       1120       1130       1140       1150
EDVNPAVATR AGLLLDTIKR PALQGLCLCL DFQFDTVVKD RPTILSKLLL 
      1160       1170       1180       1190       1200
LHFLKQDIPA LSWEFFVNRF ETLSLEAQLH LDCNKEFPFP TTITAVRTNV 
      1210       1220       1230       1240       1250
ANLSDAALWK IKRARFARNR QKSVRSLRDS VKGPVESKRA LSLPETLTSK 
      1260       1270       1280       1290       1300
IRQQSPENDN TIKDLLPEDA GIDHQTVHQL ITVLMKFMAK DESSAESDIS 
      1310       1320       1330       1340       1350
SAKAFNTVKR HLYVLLGYDQ QEGCFMIAPQ KMRLSTCFNA FIAGIAQVMD 
      1360       1370       1380       1390       1400
YNINLGKHLL PLVVQVLKYC SCPQLRHYFQ QPPRCSLWSL KPHIRQMWLK 
      1410       1420       1430       1440       1450
ALLVILYKYP YRDCDISKIL LHLIHITVNT LNAQYHSCKP HATAGPLYSD 
      1460       1470       1480       1490       1500
NSNISRYSEK EKGEIELAEY RETGALQDSL LHCVREESIP KKKLRSFKQK 
      1510       1520       1530       1540       1550
SLDIGNADSL LFTLDEHRRK SCIDRCDIEK PPTQAAYIAQ RPNDPGRSRQ 
      1560       1570       1580       1590       1600
NSATRPDNSE IPENPAMEGF PDARRPVIPE VRLNCMETFE VKVDSPVKPA 
      1610       1620       1630       1640       1650
PKEDLDLIDL SSDSTSGPEK HSILSTSDSD SLVFEPLPPL RIVESDEEEE 
      1660       1670       1680       1690       1700
TMNQGDDGPS GKNAASSPSV PSHPSVLSLS TAPLVQVSVE DCSKDFSSKD 
      1710       1720       1730       1740       1750
SGNNQSAGNT DSALITLEDP MDAEGSSKPE ELPEFSCGSP LTLKQKRDLL 
      1760       1770       1780       1790       1800
QKSFALPEMS LDDHPDPGTE GEKPGELMPS SGAKTVLLKV PEDAENPTES 
      1810       1820       1830       1840       1850
EKPDTSAESD TEQNPERKVE EDGAEESEFK IQIVPRQRKQ RKIAVSAIQR 
      1860       1870       1880       1890       1900
EYLDISFNIL DKLGEQKDPD PSTKGLSTLE MPRESSSAPT LDAGVPETSS 
      1910       1920       1930       1940       1950
HSSISKQIQP GKRQCNVPTC LNPDLEGQPL RMRGATKSSL LSAPSIVSMF 
      1960       1970       1980       1990       2000
VPAPEEFTDE QPTVMTDKCH DCGAILEEYD EETLGLAIVV LSTFIHLSPD 
      2010       2020       2030       2040       2050
LAAPLLLDIM QSVGRLASST TFSNQAESMM VPGNAAGVAK QFLRCIFHQL 
      2060       2070       2080       2090       2100
APNGIFPQLF QSTIKDGTFL RTLASSLMDF NELSSIAALS QLLEGLNNKK 
      2110       2120       2130       2140       2150
NLPAGGAMIR CLENIATFME ALPMDSPSSL WTTISNQFQT FFAKLPCVLP 
      2160       2170       2180       2190       2200
LKCSLDSSLR IMICLLKIPS TNATRSLLEP FSKLLSFVIQ NAVFTLAYLV 
      2210       2220       2230       2240       2250
ELCGLCYRAF TKERDKFYLS RSVVLELLQA LKLKSPLPDT NLLLLVQFIC 
      2260       2270       2280       2290       2300
ADAGTKLAES TILSKQMIAS VPGCGTAAME CVRQYINEVL DFMADMHTLT 
      2310       2320       2330       2340       2350
KLKSHMKTCS QPLHEDTFGG HLKVGLAQIA AMDISRGNHR DNKAVIRYLP 
      2360       2370       2380       2390       2400
WLYHPPSAMQ QGPKEFIECV SHIRLLSWLL LGSLTHNAVC PNASSPCLPI 
      2410       2420       2430       2440       2450
PLDAGSHVAD HLIVILIGFP EQSKTSVLHM CSLFHAFIFA QLWTVYCEQS 
      2460       2470       2480       2490       2500
AVATNLQNQN EFSFTAILTA LEFWSRVTPS ILQLMAHNKV MVEMVCLHVI 
      2510       2520       2530       2540       2550
SLMEALQECN STIFVKLIPM WLPMIQSNIK HLSAGLQLRL QAIQNHVNHH 
      2560       2570       2580       2590 
SLRTLPGSGQ SSAGLAALRK WLQCTQFKMA QVEIQSSEAA SQFYPL
Length:2,596
Mass (Da):290,784
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDFA4813F710021DA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9P2D8UNC79_HUMAN
Protein unc-79 homolog
UNC79 KIAA1409
2,635Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL122023 Genomic DNA No translation available.
AL136338 Genomic DNA No translation available.
AL157858 Genomic DNA No translation available.
KF455993 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000555664; ENSP00000450868; ENSG00000133958
ENST00000629205; ENSP00000487503; ENSG00000276416

UCSC genome browser

More...UCSCi		uc059eps.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL122023 Genomic DNA No translation available.
AL136338 Genomic DNA No translation available.
AL157858 Genomic DNA No translation available.
KF455993 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PRIDEiG3V2U4
ProteomicsDBi32741

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		77841, 28 antibodies

Genome annotation databases

EnsembliENST00000555664; ENSP00000450868; ENSG00000133958
ENST00000629205; ENSP00000487503; ENSG00000276416
UCSCiuc059eps.1, human

Organism-specific databases

HGNCiHGNC:19966, UNC79
OpenTargetsiENSG00000133958
VEuPathDBiHostDB:ENSG00000133958.13

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00390000011802
HOGENOMiCLU_000485_0_0_1
OMAiKKFSYQQ

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		UNC79, human

Gene expression databases

BgeeiENSG00000133958, Expressed in right hemisphere of cerebellum and 99 other tissues
ExpressionAtlasiG3V2U4, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR024855, UNC79
PANTHERiPTHR21696, PTHR21696, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3V2U4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3V2U4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 7, 2021
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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