UniProtKB - G3V2P5 (G3V2P5_HUMAN)
Protein
Submitted name:
mRNA decay activator protein ZFP36L1
Gene
ZFP36L1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 120 – 148 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 158 – 186 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- multicellular organism development Source: UniProtKB-KW
Keywordsi
Molecular function | Developmental proteinARBA annotation, RibonucleoproteinARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: mRNA decay activator protein ZFP36L1Imported |
Gene namesi | Name:ZFP36L1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1107, ZFP36L1 |
VEuPathDBi | HostDB:ENSG00000185650.9 |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmARBA annotationPTM / Processingi
Proteomic databases
MaxQBi | G3V2P5 |
PeptideAtlasi | G3V2P5 |
PRIDEi | G3V2P5 |
ProteomicsDBi | 32699 |
Expressioni
Gene expression databases
Bgeei | ENSG00000185650, Expressed in oviduct epithelium and 244 other tissues |
ExpressionAtlasi | G3V2P5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 120 – 148 | C3H1-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 158 – 186 | C3H1-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 25 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 77 – 119 | DisorderedSequence analysisAdd BLAST | 43 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 11 – 25 | PolarSequence analysisAdd BLAST | 15 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 120 – 148 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 158 – 186 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155076 |
HOGENOMi | CLU_1528578_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR007635, Tis11B_N IPR000571, Znf_CCCH IPR036855, Znf_CCCH_sf |
Pfami | View protein in Pfam PF04553, Tis11B_N, 1 hit PF00642, zf-CCCH, 2 hits |
SMARTi | View protein in SMART SM00356, ZnF_C3H1, 2 hits |
SUPFAMi | SSF90229, SSF90229, 2 hits |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
G3V2P5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRARKSGLG QRSRPTASRS EAAVQGNKML NYSAPSAGGC LLDRKAVGTP
60 70 80 90 100
AGGGFPRRHS VTLPSSKFHQ NQLLSSLKGE PAPALSSRDS RFRDRSFSEG
110 120 130 140 150
GERLLPTQKQ PGGGQVNSSR YKTELCRPFE ENGACKYGDK CQFAHGIHEL
160 170 180 190 200
RSLTRHPKYK TELCRTFHTI GFCPYGPRCH FIHNAEERRA LAGARDLSAD
RPRLQHS
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ07352 | TISB_HUMAN | mRNA decay activator protein ZFP36L... | ZFP36L1 BERG36, BRF1, ERF1, RNF162B, TIS11B | 338 | Annotation score: | ||
G3V2D5 | G3V2D5_HUMAN | mRNA decay activator protein ZFP36L... | ZFP36L1 | 176 | Annotation score: | ||
G3V515 | G3V515_HUMAN | mRNA decay activator protein ZFP36L... | ZFP36L1 | 189 | Annotation score: | ||
G3V382 | G3V382_HUMAN | mRNA decay activator protein ZFP36L... | ZFP36L1 | 69 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 207 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL132986 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000557086; ENSP00000450784; ENSG00000185650 |
UCSCi | uc059csz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL132986 Genomic DNA No translation available. |
3D structure databases
SMRi | G3V2P5 |
ModBasei | Search... |
Proteomic databases
MaxQBi | G3V2P5 |
PeptideAtlasi | G3V2P5 |
PRIDEi | G3V2P5 |
ProteomicsDBi | 32699 |
Protocols and materials databases
Antibodypediai | 37, 352 antibodies |
Genome annotation databases
Ensembli | ENST00000557086; ENSP00000450784; ENSG00000185650 |
UCSCi | uc059csz.1, human |
Organism-specific databases
HGNCi | HGNC:1107, ZFP36L1 |
OpenTargetsi | ENSG00000185650 |
VEuPathDBi | HostDB:ENSG00000185650.9 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155076 |
HOGENOMi | CLU_1528578_0_0_1 |
Miscellaneous databases
ChiTaRSi | ZFP36L1, human |
Gene expression databases
Bgeei | ENSG00000185650, Expressed in oviduct epithelium and 244 other tissues |
ExpressionAtlasi | G3V2P5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007635, Tis11B_N IPR000571, Znf_CCCH IPR036855, Znf_CCCH_sf |
Pfami | View protein in Pfam PF04553, Tis11B_N, 1 hit PF00642, zf-CCCH, 2 hits |
SMARTi | View protein in SMART SM00356, ZnF_C3H1, 2 hits |
SUPFAMi | SSF90229, SSF90229, 2 hits |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V2P5_HUMAN | |
Accessioni | G3V2P5Primary (citable) accession number: G3V2P5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | February 10, 2021 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |