UniProtKB - G3V2P5 (G3V2P5_HUMAN)

BLAST

>tr|G3V2P5|G3V2P5_HUMAN mRNA decay activator protein ZFP36L1 (Fragment) OS=Homo sapiens OX=9606 GN=ZFP36L1 PE=1 SV=1
MGRARKSGLGQRSRPTASRSEAAVQGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHS
VTLPSSKFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSR
YKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCH
FIHNAEERRALAGARDLSADRPRLQHS

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History
Entry version 54 (12 Sep 2018)
Sequence version 1 (16 Nov 2011)
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Protein

Submitted name:

mRNA decay activator protein ZFP36L1

Gene

ZFP36L1

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	120 – 148	C3H1-typePROSITE-ProRule annotationAdd BLAST		29
Zinc fingerⁱ	158 – 186	C3H1-typePROSITE-ProRule annotationAdd BLAST		29

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: mRNA decay activator protein ZFP36L1Imported
Gene namesⁱ	Name:ZFP36L1Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000185650.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1107 ZFP36L1

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000185650

OpenTargetsⁱ

ENSG00000185650

PTM / Processingⁱ

Proteomic databases

EPDⁱ	G3V2P5
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	G3V2P5
PeptideAtlas More...PeptideAtlasⁱ	G3V2P5
PRIDEⁱ	G3V2P5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000185650 Expressed in 234 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasⁱ	G3V2P5 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	G3V2P5
SMRⁱ	G3V2P5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	120 – 148	C3H1-typeInterPro annotationAdd BLAST		29
Domainⁱ	158 – 186	C3H1-typeInterPro annotationAdd BLAST		29

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	120 – 148	C3H1-typePROSITE-ProRule annotationAdd BLAST		29
Zinc fingerⁱ	158 – 186	C3H1-typePROSITE-ProRule annotationAdd BLAST		29

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1677 Eukaryota COG5063 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063262

Family and domain databases

InterProⁱ	View protein in InterPro IPR007635 Tis11B_N IPR000571 Znf_CCCH IPR036855 Znf_CCCH_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04553 Tis11B_N, 1 hit PF00642 zf-CCCH, 2 hits
SMARTⁱ	View protein in SMART SM00356 ZnF_C3H1, 2 hits
SUPFAMⁱ	SSF90229 SSF90229, 2 hits
PROSITEⁱ	View protein in PROSITE PS50103 ZF_C3H1, 2 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show all Align All

G3V2P5-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MGRARKSGLG QRSRPTASRS EAAVQGNKML NYSAPSAGGC LLDRKAVGTP 
        60         70         80         90        100
AGGGFPRRHS VTLPSSKFHQ NQLLSSLKGE PAPALSSRDS RFRDRSFSEG 
       110        120        130        140        150
GERLLPTQKQ PGGGQVNSSR YKTELCRPFE ENGACKYGDK CQFAHGIHEL 
       160        170        180        190        200
RSLTRHPKYK TELCRTFHTI GFCPYGPRCH FIHNAEERRA LAGARDLSAD 

RPRLQHS

Length:207

Mass (Da):22,819

Last modified:November 16, 2011 - v1

Checksum:ⁱFADF0D8B600FBE03

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q07352	TISB_HUMAN	mRNA decay activator protein ZFP36L... mRNA decay activator protein ZFP36L1 (Butyrate response factor 1) (EGF-response factor 1, ERF-1) (TPA-induced sequence 11b) (Zinc finger protein 36, C3H1 type-like 1, ZFP36-like 1)	ZFP36L1 BERG36, BRF1, ERF1, RNF162B, TIS11B	338	Annotation score:
G3V2D5	G3V2D5_HUMAN	mRNA decay activator protein ZFP36L... mRNA decay activator protein ZFP36L1	ZFP36L1	176	Annotation score:
G3V515	G3V515_HUMAN	mRNA decay activator protein ZFP36L... mRNA decay activator protein ZFP36L1	ZFP36L1	189	Annotation score:
G3V382	G3V382_HUMAN	mRNA decay activator protein ZFP36L... mRNA decay activator protein ZFP36L1	ZFP36L1	69	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	207	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL132986 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL132986 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000557086; ENSP00000450784; ENSG00000185650
UCSC genome browser More...UCSCⁱ	uc059csz.1 human

Protein	Similar proteins		Species	Score	Length	Source
G3V2P5	ZFP36L1 isoform 4 (Fragment)		PONAB		207	UniRef90_G3V2P5
ZFP36L1 isoform 4 (Fragment)		PANTR		207

Protein	Similar proteins		Species	Score	Length	Source
G3V2P5	ZFP36L1 isoform 4 (Fragment)		PANTR		207	UniRef50_G3V2P5
ZFP36L1 isoform 4 (Fragment)		PONAB		207
UPI00077A854A		ACRDI		228

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL132986 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL132986 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	G3V2P5
SMRⁱ	G3V2P5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	G3V2P5
MaxQBⁱ	G3V2P5
PeptideAtlasⁱ	G3V2P5
PRIDEⁱ	G3V2P5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000557086; ENSP00000450784; ENSG00000185650
UCSCⁱ	uc059csz.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000185650.9
HGNCⁱ	HGNC:1107 ZFP36L1
OpenTargetsⁱ	ENSG00000185650
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1677 Eukaryota COG5063 LUCA
GeneTreeⁱ	ENSGT00530000063262

Miscellaneous databases

ChiTaRSⁱ	ZFP36L1 human

ChiTaRSⁱ

ZFP36L1 human

Gene expression databases

Bgeeⁱ	ENSG00000185650 Expressed in 234 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasⁱ	G3V2P5 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR007635 Tis11B_N IPR000571 Znf_CCCH IPR036855 Znf_CCCH_sf
Pfamⁱ	View protein in Pfam PF04553 Tis11B_N, 1 hit PF00642 zf-CCCH, 2 hits
SMARTⁱ	View protein in SMART SM00356 ZnF_C3H1, 2 hits
SUPFAMⁱ	SSF90229 SSF90229, 2 hits
PROSITEⁱ	View protein in PROSITE PS50103 ZF_C3H1, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	G3V2P5_HUMAN
Accessionⁱ	G3V2P5Primary (citable) accession number: G3V2P5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 16, 2011
	Last sequence update:	November 16, 2011
	Last modified:	September 12, 2018
	This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - G3V2P5 (G3V2P5_HUMAN)

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mRNA decay activator protein ZFP36L1

ZFP36L1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ