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Protein
Submitted name:

mRNA decay activator protein ZFP36L1

Gene

ZFP36L1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri120 – 148C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri158 – 186C3H1-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
mRNA decay activator protein ZFP36L1Imported
Gene namesi
Name:ZFP36L1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000185650.9
HGNCiHGNC:1107 ZFP36L1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185650

PTM / Processingi

Proteomic databases

EPDiG3V2P5
MaxQBiG3V2P5
PeptideAtlasiG3V2P5
PRIDEiG3V2P5

Expressioni

Gene expression databases

BgeeiENSG00000185650 Expressed in 234 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiG3V2P5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliG3V2P5
SMRiG3V2P5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 148C3H1-typeInterPro annotationAdd BLAST29
Domaini158 – 186C3H1-typeInterPro annotationAdd BLAST29

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri120 – 148C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri158 – 186C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1677 Eukaryota
COG5063 LUCA
GeneTreeiENSGT00530000063262

Family and domain databases

InterProiView protein in InterPro
IPR007635 Tis11B_N
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf
PfamiView protein in Pfam
PF04553 Tis11B_N, 1 hit
PF00642 zf-CCCH, 2 hits
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF90229 SSF90229, 2 hits
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

G3V2P5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRARKSGLG QRSRPTASRS EAAVQGNKML NYSAPSAGGC LLDRKAVGTP
60 70 80 90 100
AGGGFPRRHS VTLPSSKFHQ NQLLSSLKGE PAPALSSRDS RFRDRSFSEG
110 120 130 140 150
GERLLPTQKQ PGGGQVNSSR YKTELCRPFE ENGACKYGDK CQFAHGIHEL
160 170 180 190 200
RSLTRHPKYK TELCRTFHTI GFCPYGPRCH FIHNAEERRA LAGARDLSAD

RPRLQHS
Length:207
Mass (Da):22,819
Last modified:November 16, 2011 - v1
Checksum:iFADF0D8B600FBE03
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q07352TISB_HUMAN
mRNA decay activator protein ZFP36L...
ZFP36L1 BERG36, BRF1, ERF1, RNF162B, TIS11B
338Annotation score:
G3V2D5G3V2D5_HUMAN
mRNA decay activator protein ZFP36L...
ZFP36L1
176Annotation score:
G3V515G3V515_HUMAN
mRNA decay activator protein ZFP36L...
ZFP36L1
189Annotation score:
G3V382G3V382_HUMAN
mRNA decay activator protein ZFP36L...
ZFP36L1
69Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei207Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132986 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000557086; ENSP00000450784; ENSG00000185650
UCSCiuc059csz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132986 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliG3V2P5
SMRiG3V2P5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiG3V2P5
MaxQBiG3V2P5
PeptideAtlasiG3V2P5
PRIDEiG3V2P5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000557086; ENSP00000450784; ENSG00000185650
UCSCiuc059csz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000185650.9
HGNCiHGNC:1107 ZFP36L1
OpenTargetsiENSG00000185650
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1677 Eukaryota
COG5063 LUCA
GeneTreeiENSGT00530000063262

Miscellaneous databases

ChiTaRSiZFP36L1 human

Gene expression databases

BgeeiENSG00000185650 Expressed in 234 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiG3V2P5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007635 Tis11B_N
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf
PfamiView protein in Pfam
PF04553 Tis11B_N, 1 hit
PF00642 zf-CCCH, 2 hits
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF90229 SSF90229, 2 hits
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiG3V2P5_HUMAN
AccessioniPrimary (citable) accession number: G3V2P5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 12, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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