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Protein
Submitted name:

Retinol dehydrogenase 11

Gene

RDH11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Retinol dehydrogenase 11Imported
Gene namesi
Name:RDH11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000072042.12
HGNCiHGNC:17964 RDH11

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000072042

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500841472721 – 186Sequence analysisAdd BLAST166

Proteomic databases

PeptideAtlasiG3V234
PRIDEiG3V234

Expressioni

Gene expression databases

BgeeiENSG00000072042 Expressed in 236 organ(s), highest expression level in pigmented layer of retina
ExpressionAtlasiG3V234 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliG3V234
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119068

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

G3V234-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVELMFPLLL LLLPFLLYMA APQIRKMLSS GVCTSTVQLP GKVVVVTGAN
60 70 80 90 100
TGIGKETAKE LAQREEKHLH VLINNAGVMM CPYSKTADGF EMHIGVNHLG
110 120 130 140 150
HFLLTHLLLE KLKESAPSRI VNVSSLAHHL GRIHFHNLQG EKFYNAGLAY
160 170 180
CHSKLANILF TQELARRLKG SGVTTYSVHP GTVQSE
Length:186
Mass (Da):20,479
Last modified:October 5, 2016 - v8
Checksum:i49129770443E68EC
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8TC12RDH11_HUMAN
Retinol dehydrogenase 11
RDH11 ARSDR1, PSDR1, SDR7C1, CGI-82
318Annotation score:
G3V2G6G3V2G6_HUMAN
Retinol dehydrogenase 11
RDH11
178Annotation score:
G3V3K0G3V3K0_HUMAN
Retinol dehydrogenase 11
RDH11
61Annotation score:
G3V510G3V510_HUMAN
Retinol dehydrogenase 11
RDH11
62Annotation score:
H0YJ46H0YJ46_HUMAN
Retinol dehydrogenase 11
RDH11
204Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei186Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049779 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000557726; ENSP00000450435; ENSG00000072042
UCSCiuc059crj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049779 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliG3V234
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiG3V234
PRIDEiG3V234

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000557726; ENSP00000450435; ENSG00000072042
UCSCiuc059crj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000072042.12
HGNCiHGNC:17964 RDH11
OpenTargetsiENSG00000072042
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119068

Miscellaneous databases

ChiTaRSiRDH11 human

Gene expression databases

BgeeiENSG00000072042 Expressed in 236 organ(s), highest expression level in pigmented layer of retina
ExpressionAtlasiG3V234 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V234_HUMAN
AccessioniPrimary (citable) accession number: G3V234
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 49 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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