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Protein
Submitted name:

ELK3, ETS-domain protein (SRF accessory protein 2), isoform CRA_b

Gene

ELK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ELK3, ETS-domain protein (SRF accessory protein 2), isoform CRA_bImported
Submitted name:
ETS domain-containing protein Elk-3Imported
Gene namesi
Name:ELK3Imported
ORF Names:hCG_32371Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111145.7
HGNCiHGNC:3325 ELK3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111145

PTM / Processingi

Proteomic databases

PRIDEiG3V1Z7

Expressioni

Gene expression databases

BgeeiENSG00000111145 Expressed in 232 organ(s), highest expression level in visceral pleura

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 69ETSInterPro annotationAdd BLAST65

Sequence similaritiesi

Belongs to the ETS family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
GeneTreeiENSGT00760000118907

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

G3V1Z7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESAITLWQF LLQLLLDQKH EHLICWTSND GEFKLLKAEE VAKLWGLRKN
60 70 80 90 100
KTNMNYDKLS RALRYYYDKT PNGLLLTPSP LLSSIHFWSS LSPVAPLSPA
110 120 130 140
RLQGPSTLFQ FPTLLNGHMP VPIPSLDRAA SPVLLSSNSQ KS
Length:142
Mass (Da):16,032
Last modified:November 16, 2011 - v1
Checksum:i6AFDDB05057E031B
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P41970ELK3_HUMAN
ETS domain-containing protein Elk-3
ELK3 NET, SAP2
407Annotation score:
F8VUJ0F8VUJ0_HUMAN
ETS domain-containing protein Elk-3
ELK3
159Annotation score:
F8VZQ0F8VZQ0_HUMAN
ETS domain-containing protein Elk-3
ELK3
38Annotation score:
H0YIH6H0YIH6_HUMAN
ETS domain-containing protein Elk-3
ELK3
102Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008149 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97562.1
UniGeneiHs.46523
Hs.718709

Genome annotation databases

EnsembliENST00000552142; ENSP00000449430; ENSG00000111145
UCSCiuc058sae.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008149 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97562.1
UniGeneiHs.46523
Hs.718709

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiG3V1Z7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000552142; ENSP00000449430; ENSG00000111145
UCSCiuc058sae.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000111145.7
HGNCiHGNC:3325 ELK3
OpenTargetsiENSG00000111145
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
GeneTreeiENSGT00760000118907

Miscellaneous databases

ChiTaRSiELK3 human

Gene expression databases

BgeeiENSG00000111145 Expressed in 232 organ(s), highest expression level in visceral pleura

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG3V1Z7_HUMAN
AccessioniPrimary (citable) accession number: G3V1Z7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 7, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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