UniProtKB - G3V1V1 (G3V1V1_HUMAN)
Protein
Submitted name:
Zinc finger CCHC-type and RNA binding motif 1, isoform CRA_b
Gene
ZCRB1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger CCHC-type and RNA binding motif 1, isoform CRA_bImportedSubmitted name: Zinc finger CCHC-type and RNA-binding motif-containing protein 1Imported |
Gene namesi | Name:ZCRB1Imported ORF Names:hCG_1818570Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:29620 ZCRB1 |
PTM / Processingi
Proteomic databases
MaxQBi | G3V1V1 |
PeptideAtlasi | G3V1V1 |
PRIDEi | G3V1V1 |
ProteomicsDBi | 32450 |
Expressioni
Gene expression databases
Bgeei | ENSG00000139168 Expressed in 207 organ(s), highest expression level in oocyte |
ExpressionAtlasi | G3V1V1 baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 47 | RRMInterPro annotationAdd BLAST | 47 | |
Domaini | 65 – 81 | CCHC-typeInterPro annotationAdd BLAST | 17 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 75 – 176 | DisorderedSequence analysisAdd BLAST | 102 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 106 – 122 | AcidicSequence analysisAdd BLAST | 17 | |
Compositional biasi | 156 – 176 | PolyampholyteSequence analysisAdd BLAST | 21 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | ENOG410IQXP Eukaryota ENOG4111IY7 LUCA |
GeneTreei | ENSGT00730000111061 |
OrthoDBi | 1422822at2759 |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR001878 Znf_CCHC IPR036875 Znf_CCHC_sf |
Pfami | View protein in Pfam PF00076 RRM_1, 1 hit PF00098 zf-CCHC, 1 hit |
SMARTi | View protein in SMART SM00343 ZnF_C2HC, 1 hit |
SUPFAMi | SSF54928 SSF54928, 1 hit SSF57756 SSF57756, 1 hit |
PROSITEi | View protein in PROSITE PS50102 RRM, 1 hit PS50158 ZF_CCHC, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
G3V1V1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKDKDTRKSK GVAFILFLDK DSAQNCTRAI NNKQLFGRVI KASIAIDNGR
60 70 80 90 100
AAEFIRRRNY FDKSKCYECG ESGHLSYACP KNMLGEREPP KKKEKKKKKK
110 120 130 140 150
APEPEEEIEE VEESEDEGED PALDSLSQAI AFQQAKIEEE QKKWKPSSGV
160 170
PSTSDDSRRP RIKKSTYFSD EEELSD
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8TBF4 | ZCRB1_HUMAN | Zinc finger CCHC-type and RNA-bindi... | ZCRB1 | 217 | Annotation score: | ||
F8VXY6 | F8VXY6_HUMAN | Zinc finger CCHC-type and RNA-bindi... | ZCRB1 | 133 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC079684 Genomic DNA No translation available. CH471111 Genomic DNA Translation: EAW57844.1 |
RefSeqi | XP_016875613.1, XM_017020124.1 |
Genome annotation databases
Ensembli | ENST00000552673; ENSP00000446732; ENSG00000139168 |
GeneIDi | 85437 |
UCSCi | uc058mue.1 human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC079684 Genomic DNA No translation available. CH471111 Genomic DNA Translation: EAW57844.1 |
RefSeqi | XP_016875613.1, XM_017020124.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | G3V1V1 |
PeptideAtlasi | G3V1V1 |
PRIDEi | G3V1V1 |
ProteomicsDBi | 32450 |
Genome annotation databases
Ensembli | ENST00000552673; ENSP00000446732; ENSG00000139168 |
GeneIDi | 85437 |
UCSCi | uc058mue.1 human |
Organism-specific databases
CTDi | 85437 |
HGNCi | HGNC:29620 ZCRB1 |
OpenTargetsi | ENSG00000139168 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG410IQXP Eukaryota ENOG4111IY7 LUCA |
GeneTreei | ENSGT00730000111061 |
OrthoDBi | 1422822at2759 |
Miscellaneous databases
ChiTaRSi | ZCRB1 human |
GenomeRNAii | 85437 |
Gene expression databases
Bgeei | ENSG00000139168 Expressed in 207 organ(s), highest expression level in oocyte |
ExpressionAtlasi | G3V1V1 baseline and differential |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR001878 Znf_CCHC IPR036875 Znf_CCHC_sf |
Pfami | View protein in Pfam PF00076 RRM_1, 1 hit PF00098 zf-CCHC, 1 hit |
SMARTi | View protein in SMART SM00343 ZnF_C2HC, 1 hit |
SUPFAMi | SSF54928 SSF54928, 1 hit SSF57756 SSF57756, 1 hit |
PROSITEi | View protein in PROSITE PS50102 RRM, 1 hit PS50158 ZF_CCHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V1V1_HUMAN | |
Accessioni | G3V1V1Primary (citable) accession number: G3V1V1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | October 16, 2019 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |