UniProtKB - G3V1R7 (G3V1R7_HUMAN)
Protein
Submitted name:
Solute carrier family 27 (Fatty acid transporter), member 2, isoform CRA_b
Gene
SLC27A2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- long-chain fatty acid-CoA ligase activity Source: InterPro
- very long-chain fatty acid-CoA ligase activity Source: InterPro
GO - Biological processi
- fatty acid transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Solute carrier family 27 (Fatty acid transporter), member 2, isoform CRA_bImportedSubmitted name: Very long-chain acyl-CoA synthetaseImported |
Gene namesi | Name:SLC27A2Imported ORF Names:hCG_39815Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000140284.10 |
HGNCi | HGNC:10996, SLC27A2 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 31 – 53 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000140284, Expressed in nephron tubule and 188 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 252 | AMP-bindingInterPro annotationAdd BLAST | 252 | |
Domaini | 264 – 337 | AMP-binding_CInterPro annotationAdd BLAST | 74 |
Sequence similaritiesi
Belongs to the ATP-dependent AMP-binding enzyme family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000161137 |
HOGENOMi | CLU_000022_46_1_1 |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf IPR030305, FATP2 |
PANTHERi | PTHR43107:SF13, PTHR43107:SF13, 1 hit |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
G3V1R7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MITHQRIWYG TGLTFVSGLK ADDVIYITLP FYHSAALLIG IHGCIVAGAT
60 70 80 90 100
LALRTKFSAS QFWDDCRKYN VTVIQYIGEL LRYLCNSPQK PNDRDHKVRL
110 120 130 140 150
ALGNGLRGDV WRQFVKRFGD ICIYEFYAAT EGNIGFMNYA RKVGAVGRVN
160 170 180 190 200
YLQKKIITYD LIKYDVEKDE PVRDENGYCV RVPKGEVGLL VCKITQLTPF
210 220 230 240 250
NGYAGAKAQT EKKKLRDVFK KGDLYFNSGD LLMVDHENFI YFHDRVGDTF
260 270 280 290 300
RWKGENVATT EVADTVGLVD FVQEVNVYGV HVPDHEGRIG MASIKMKENH
310 320 330 340 350
EFDGKKLFQH IADYLPSYAR PRFLRIQDTI EITGTFKHRK MTLVEEGFNP
360 370 380
AVIKDALYFL DDTAKMYVPM TEDIYNAISA KTLKL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketO14975 | S27A2_HUMAN | Very long-chain acyl-CoA synthetase | SLC27A2 ACSVL1, FACVL1, FATP2, VLACS | 620 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009753 Genomic DNA No translation available. CH471082 Genomic DNA Translation: EAW77385.1 |
Genome annotation databases
Ensembli | ENST00000544960; ENSP00000444549; ENSG00000140284 |
UCSCi | uc001zxx.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009753 Genomic DNA No translation available. CH471082 Genomic DNA Translation: EAW77385.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | G3V1R7 |
PRIDEi | G3V1R7 |
ProteomicsDBi | 32418 |
Protocols and materials databases
Antibodypediai | 12170, 176 antibodies |
Genome annotation databases
Ensembli | ENST00000544960; ENSP00000444549; ENSG00000140284 |
UCSCi | uc001zxx.4, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000140284.10 |
HGNCi | HGNC:10996, SLC27A2 |
OpenTargetsi | ENSG00000140284 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161137 |
HOGENOMi | CLU_000022_46_1_1 |
Miscellaneous databases
ChiTaRSi | SLC27A2, human |
Gene expression databases
Bgeei | ENSG00000140284, Expressed in nephron tubule and 188 other tissues |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf IPR030305, FATP2 |
PANTHERi | PTHR43107:SF13, PTHR43107:SF13, 1 hit |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V1R7_HUMAN | |
Accessioni | G3V1R7Primary (citable) accession number: G3V1R7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | October 7, 2020 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |