The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - G3V1M7 (G3V1M7_HUMAN)
Protein
Submitted name:
Very long-chain-specific acyl-CoA dehydrogenase, mitochondrial
Gene
ACADVL
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- acyl-CoA dehydrogenase activity Source: InterPro
Keywordsi
Molecular function | OxidoreductaseARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Very long-chain-specific acyl-CoA dehydrogenase, mitochondrial |
Gene namesi | Name:ACADVL |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:92, ACADVL |
VEuPathDBi | HostDB:ENSG00000072778 |
PTM / Processingi
Proteomic databases
MaxQBi | G3V1M7 |
PeptideAtlasi | G3V1M7 |
PRIDEi | G3V1M7 |
ProteomicsDBi | 32382 |
Expressioni
Gene expression databases
Bgeei | ENSG00000072778, Expressed in left lobe of thyroid gland and 248 other tissues |
ExpressionAtlasi | G3V1M7, baseline and differential |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 93 | Acyl-CoA_dh_1InterPro annotationAdd BLAST | 92 |
Phylogenomic databases
GeneTreei | ENSGT00940000158535 |
HOGENOMi | CLU_055384_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR006089, Acyl-CoA_DH_CS IPR036250, AcylCo_DH-like_C IPR009075, AcylCo_DH/oxidase_C |
Pfami | View protein in Pfam PF00441, Acyl-CoA_dh_1, 1 hit |
SUPFAMi | SSF47203, SSF47203, 1 hit |
PROSITEi | View protein in PROSITE PS00073, ACYL_COA_DH_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
G3V1M7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XKLARMVMLQ YVTESMAYMV SANMDQGATD FQIEAAISKI FGSEAAWKVT
60 70 80 90 100
DECIQIMGGM GFMKEPGVER VLRDLRIFRI FEGTNDILRL FVALQGCMDK
110 120 130 140 150
GKELSGLGSA LKNPFGNAGL LLGEAGKQLR RRAGLGSGLS LSGLVHPELS
160 170 180 190 200
RSGELAVRAL EQFATVVEAK LIKHKKGIVS EEAGRECLSR RGPGPGSQPA
210 220 230 240 250
QIYFHLLLPA RASRSLSEGH PTAQHEKMLC DTWCIEAAAR IREGMAALQS
260 270 280
DPWQQELYRN FKSISKALVE RGGVVTSNPL GF
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP49748 | ACADV_HUMAN | Very long-chain specific acyl-CoA d... | ACADVL VLCAD | 655 | Annotation score: | ||
J3QKU9 | J3QKU9_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 155 | Annotation score: | ||
K7EQP4 | K7EQP4_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 224 | Annotation score: | ||
K7EJW8 | K7EJW8_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 157 | Annotation score: | ||
J9JID6 | J9JID6_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 39 | Annotation score: | ||
J3KSR4 | J3KSR4_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 204 | Annotation score: | ||
J3KS89 | J3KS89_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 76 | Annotation score: | ||
J3QRJ8 | J3QRJ8_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 194 | Annotation score: | ||
K7EMF8 | K7EMF8_HUMAN | Very long-chain-specific acyl-CoA d... | ACADVL | 45 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120057 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000542255.6; ENSP00000442082.2; ENSG00000072778.20 |
UCSCi | uc060ajj.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC120057 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
MaxQBi | G3V1M7 |
PeptideAtlasi | G3V1M7 |
PRIDEi | G3V1M7 |
ProteomicsDBi | 32382 |
Protocols and materials databases
Antibodypediai | 11798, 302 antibodies from 34 providers |
Genome annotation databases
Ensembli | ENST00000542255.6; ENSP00000442082.2; ENSG00000072778.20 |
UCSCi | uc060ajj.1, human |
Organism-specific databases
HGNCi | HGNC:92, ACADVL |
OpenTargetsi | ENSG00000072778 |
VEuPathDBi | HostDB:ENSG00000072778 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158535 |
HOGENOMi | CLU_055384_0_0_1 |
Miscellaneous databases
ChiTaRSi | ACADVL, human |
Gene expression databases
Bgeei | ENSG00000072778, Expressed in left lobe of thyroid gland and 248 other tissues |
ExpressionAtlasi | G3V1M7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006089, Acyl-CoA_DH_CS IPR036250, AcylCo_DH-like_C IPR009075, AcylCo_DH/oxidase_C |
Pfami | View protein in Pfam PF00441, Acyl-CoA_dh_1, 1 hit |
SUPFAMi | SSF47203, SSF47203, 1 hit |
PROSITEi | View protein in PROSITE PS00073, ACYL_COA_DH_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G3V1M7_HUMAN | |
Accessioni | G3V1M7Primary (citable) accession number: G3V1M7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | October 3, 2012 | |
Last modified: | May 25, 2022 | |
This is version 60 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |