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Entry version 78 (16 Oct 2019)
Sequence version 1 (16 Nov 2011)
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Protein
Submitted name:

HCG38403, isoform CRA_b

Gene

TENM2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HCG38403, isoform CRA_bImported
Submitted name:
Teneurin-2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TENM2Imported
ORF Names:hCG_38403Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29943 TENM2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei254 – 279HelicalSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000145934

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi503 ↔ 512PROSITE-ProRule annotation
Disulfide bondi537 ↔ 546PROSITE-ProRule annotation
Disulfide bondi585 ↔ 595PROSITE-ProRule annotation
Disulfide bondi604 ↔ 613PROSITE-ProRule annotation
Disulfide bondi649 ↔ 659PROSITE-ProRule annotation
Disulfide bondi666 ↔ 675PROSITE-ProRule annotation
Disulfide bondi689 ↔ 699PROSITE-ProRule annotation
Disulfide bondi710 ↔ 719PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
G3V106

PeptideAtlas

More...
PeptideAtlasi
G3V106

PRoteomics IDEntifications database

More...
PRIDEi
G3V106

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
32219

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145934 Expressed in 153 organ(s), highest expression level in left ventricle myocardium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
G3V106 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 254Teneurin N-terminalInterPro annotationAdd BLAST254
Domaini477 – 513EGF-likeInterPro annotationAdd BLAST37
Domaini515 – 547EGF-likeInterPro annotationAdd BLAST33
Domaini581 – 614EGF-likeInterPro annotationAdd BLAST34
Domaini645 – 676EGF-likeInterPro annotationAdd BLAST32
Domaini685 – 720EGF-likeInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni47 – 150DisorderedSequence analysisAdd BLAST104

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi76 – 124PolarSequence analysisAdd BLAST49

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1225 Eukaryota
KOG4659 Eukaryota
ENOG410XQQD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182725

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR008969 CarboxyPept-like_regulatory
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR011044 Quino_amine_DH_bsu
IPR022385 Rhs_assc_core
IPR027689 Ten-2/3
IPR009471 Ten_N
IPR028916 Tox-GHH_dom
IPR006530 YD

The PANTHER Classification System

More...
PANTHERi
PTHR11219:SF8 PTHR11219:SF8, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06484 Ten_N, 1 hit
PF15636 Tox-GHH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 8 hits
SM00179 EGF_CA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49464 SSF49464, 1 hit
SSF50969 SSF50969, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03696 Rhs_assc_core, 1 hit
TIGR01643 YD_repeat_2x, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 6 hits
PS01186 EGF_2, 5 hits
PS50026 EGF_3, 5 hits
PS51361 TENEURIN_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

G3V106-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSPPLLIIS VAGTIECKPD HLLWRPGSTS PQSVSFLHGK VVMESLGRPI
60 70 80 90 100
PPTSSPSLLP SAQLPSSHNP PPVSCQMPLL DSNTSHQIMD TNPDEEFSPN
110 120 130 140 150
SYLLRACSGP QQASSSGPPN HHSQSTLRPP LPPPHNHTLS HHHSSANSLN
160 170 180 190 200
RNSLTNRRSQ IHAPAPAPND LATTPESVQL QDSWVLNSNV PLETRHFLFK
210 220 230 240 250
TSSGSTPLFS SSSPGYPLTS GTVYTPPPRL LPRNTFSRKA FKLKKPSKYC
260 270 280 290 300
SWKCAALSAI AAALLLAILL AYFIAMHLLG LNWQLQPADG HTFNNGIRTG
310 320 330 340 350
LPGNDDVATM PSGGKVPWSL KNSSIDSGEA EVGRRVTQEV PPGVFWRSQI
360 370 380 390 400
HISQPQFLKF NISLGKDALF GVYIRRGLPP SHAQYDFMER LDGKEKWSVV
410 420 430 440 450
ESPRERRSIQ TLVQNEAVFV QYLDVGLWHL AFYNDGKDKE MVSFNTVVLD
460 470 480 490 500
SVQDCPRNCH GNGECVSGVC HCFPGFLGAD CAKAACPVLC SGNGQYSKGT
510 520 530 540 550
CQCYSGWKGA ECDVPMNQCI DPSCGGHGSC IDGNCVCSAG YKGEHCEEVD
560 570 580 590 600
CLDPTCSSHG VCVNGECLCS PGWGGLNCEL ARVQCPDQCS GHGTYLPDTG
610 620 630 640 650
LCSCDPNWMG PDCSVEVCSV DCGTHGVCIG GACRCEEGWT GAACDQRVCH
660 670 680 690 700
PRCIEHGTCK DGKCECREGW NGEHCTIGRQ TAGTETDGCP DLCNGNGRCT
710 720 730 740 750
LGQNSWQCVC QTGWRGPGCN VAMETSCADN KDNEGDGLVD CLDPDCCLQS
760 770 780 790 800
ACQNSLLCRG SRDPLDIIQQ GQTDWPAVKS FYDRIKLLAG KDSTHIIPGE
810 820 830 840 850
NPFNSSLVSL IRGQVVTTDG TPLVGVNVSF VKYPKYGYTI TRQDGTFDLI
860 870 880 890 900
ANGGASLTLH FERAPFMSQE RTVWLPWNSF YAMDTLVMKT EENSIPSCDL
910 920 930 940 950
SGFVRPDPII ISSPLSTFFS AAPGQNPIVP ETQVLHEEIE LPGSNVKLRY
960 970 980 990 1000
LSSRTAGYKS LLKITMTQST VPLNLIRVHL MVAVEGHLFQ KSFQASPNLA
1010 1020 1030 1040 1050
YTFIWDKTDA YGQRVYGLSD AVVSVGFEYE TCPSLILWEK RTALLQGFEL
1060 1070 1080 1090 1100
DPSNLGGWSL DKHHILNVKS GILHKGTGEN QFLTQQPAII TSIMGNGRRR
1110 1120 1130 1140 1150
SISCPSCNGL AEGNKLLAPV ALAVGIDGSL YVGDFNYIRR IFPSRNVTSI
1160 1170 1180 1190 1200
LELRNKEFKH SNNPAHKYYL AVDPVSGSLY VSDTNSRRIY RVKSLSGTKD
1210 1220 1230 1240 1250
LAGNSEVVAG TGEQCLPFDE ARCGDGGKAI DATLMSPRGI AVDKNGLMYF
1260 1270 1280 1290 1300
VDATMIRKVD QNGIISTLLG SNDLTAVRPL SCDSSMDVAQ VRLEWPTDLA
1310 1320 1330 1340 1350
VNPMDNSLYV LENNVILRIT ENHQVSIIAG RPMHCQVPGI DYSLSKLAIH
1360 1370 1380 1390 1400
SALESASAIA ISHTGVLYIT ETDEKKINRL RQVTTNGEIC LLAGAASDCD
1410 1420 1430 1440 1450
CKNDVNCNCY SGDDAYATDA ILNSPSSLAV APDGTIYIAD LGNIRIRAVS
1460 1470 1480 1490 1500
KNKPVLNAFN QYEAASPGEQ ELYVFNADGI HQYTVSLVTG EYLYNFTYST
1510 1520 1530 1540 1550
DNDVTELIDN NGNSLKIRRD SSGMPRHLLM PDNQIITLTV GTNGGLKVVS
1560 1570 1580 1590 1600
TQNLELGLMT YDGNTGLLAT KSDETGWTTF YDYDHEGRLT NVTRPTGVVT
1610 1620 1630 1640 1650
SLHREMEKSI TIDIENSNRD DDVTVITNLS SVEASYTVVQ DQVRNSYQLC
1660 1670 1680 1690 1700
NNGTLRVMYA NGMGISFHSE PHVLAGTITP TIGRCNISLP MENGLNSIEW
1710 1720 1730 1740 1750
RLRKEQIKGK VTIFGRKLRV HGRNLLSIDY DRNIRTEKIY DDHRKFTLRI
1760 1770 1780 1790 1800
IYDQVGRPFL WLPSSGLAAV NVSYFFNGRL AGLQRGAMSE RTDIDKQGRI
1810 1820 1830 1840 1850
VSRMFADGKV WSYSYLDKSM VLLLQSQRQY IFEYDSSDRL LAVTMPSVAR
1860 1870 1880 1890 1900
HSMSTHTSIG YIRNIYNPPE SNASVIFDYS DDGRILKTSF LGTGRQVFYK
1910 1920 1930 1940 1950
YGKLSKLSEI VYDSTAVTFG YDETTGVLKM VNLQSGGFSC TIRYRKIGPL
1960 1970 1980 1990 2000
VDKQIYRFSE EGMVNARFDY TYHDNSFRIA SIKPVISETP LPVDLYRYDE
2010 2020 2030 2040 2050
ISGKVEHFGK FGVIYYDINQ IITTAVMTLS KHFDTHGRIK EVQYEMFRSL
2060 2070 2080 2090 2100
MYWMTVQYDS MGRVIKRELK LGPYANTTKY TYDYDGDGQL QSVAVNDRPT
2110 2120 2130 2140 2150
WRYSYDLNGN LHLLNPGNSV RLMPLRYDLR DRITRLGDVQ YKIDDDGYLC
2160 2170 2180 2190 2200
QRGSDIFEYN SKGLLTRAYN KASGWSVQYR YDGVGRRASY KTNLGHHLQY
2210 2220 2230 2240 2250
FYSDLHNPTR ITHVYNHSNS EITSLYYDLQ GHLFAMESSS GEEYYVASDN
2260 2270 2280 2290 2300
TGTPLAVFSI NGLMIKQLQY TAYGEIYYDS NPDFQMVIGF HGGLYDPLTK
2310 2320 2330 2340 2350
LVHFTQRDYD VLAGRWTSPD YTMWKNVGKE PAPFNLYMFK SNNPLSSELD
2360 2370 2380 2390 2400
LKNYVTDVKS WLVMFGFQLS NIIPGFPRAK MYFVPPPYEL SESQASENGQ
2410 2420 2430 2440 2450
LITGVQQTTE RHNQAFMALE GQVITKKLHA SIREKAGHWF ATTTPIIGKG
2460 2470 2480 2490 2500
IMFAIKEGRV TTGVSSIASE DSRKVASVLN NAYYLDKMHY SIEGKDTHYF
2510 2520 2530 2540 2550
VKIGSADGDL VTLGTTIGRK VLESGVNVTV SQPTLLVNGR TRRFTNIEFQ
2560 2570 2580 2590 2600
YSTLLLSIRY GLTPDTLDEE KARVLDQARQ RALGTAWAKE QQKARDGREG
2610 2620 2630 2640 2650
SRLWTEGEKQ QLLSTGRVQG YEGYYVLPVE QYPELADSSS NIQFLRQNEM

GKR
Length:2,653
Mass (Da):294,060
Last modified:November 16, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i397A10EC8CC46F6A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NT68TEN2_HUMAN
Teneurin-2
TENM2 KIAA1127, ODZ2, TNM2
2,774Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VNQ3F8VNQ3_HUMAN
Teneurin-2
TENM2
2,535Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
KC877165 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61512.1

NCBI Reference Sequences

More...
RefSeqi
XP_016865153.1, XM_017009664.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000519204; ENSP00000428964; ENSG00000145934

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57451

UCSC genome browser

More...
UCSCi
uc003lzt.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
KC877165 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW61512.1
RefSeqiXP_016865153.1, XM_017009664.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

MaxQBiG3V106
PeptideAtlasiG3V106
PRIDEiG3V106
ProteomicsDBi32219

Genome annotation databases

EnsembliENST00000519204; ENSP00000428964; ENSG00000145934
GeneIDi57451
UCSCiuc003lzt.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57451
HGNCiHGNC:29943 TENM2
OpenTargetsiENSG00000145934

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1225 Eukaryota
KOG4659 Eukaryota
ENOG410XQQD LUCA
GeneTreeiENSGT00950000182725

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TENM2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57451

Gene expression databases

BgeeiENSG00000145934 Expressed in 153 organ(s), highest expression level in left ventricle myocardium
ExpressionAtlasiG3V106 baseline and differential

Family and domain databases

Gene3Di2.120.10.30, 2 hits
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR008969 CarboxyPept-like_regulatory
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR011044 Quino_amine_DH_bsu
IPR022385 Rhs_assc_core
IPR027689 Ten-2/3
IPR009471 Ten_N
IPR028916 Tox-GHH_dom
IPR006530 YD
PANTHERiPTHR11219:SF8 PTHR11219:SF8, 1 hit
PfamiView protein in Pfam
PF06484 Ten_N, 1 hit
PF15636 Tox-GHH, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 8 hits
SM00179 EGF_CA, 2 hits
SUPFAMiSSF49464 SSF49464, 1 hit
SSF50969 SSF50969, 1 hit
TIGRFAMsiTIGR03696 Rhs_assc_core, 1 hit
TIGR01643 YD_repeat_2x, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 6 hits
PS01186 EGF_2, 5 hits
PS50026 EGF_3, 5 hits
PS51361 TENEURIN_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG3V106_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G3V106
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 16, 2019
This is version 78 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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